Introduction to ncbi, embl, ddbj

INTRODUCTION.
NCBI.
EMBL.
DDBJ.
CONCLUSION.
REFERENSE.
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health.

The NCBI is located in Bethesda, Maryland and was founded in 1988 through legislation sponsored by Senator Claude Pepper.

The NCBI houses a series of databases relevant to biotechnology and biomedicine. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for the biomedical literature.

All these databases are available online through the Entrez search engine.

1. INTRODUCTION TO NCBI , EMBL & DDBJ. By KAUSHAL KUMAR SAHU Assistant Professor (Ad Hoc) Department of Biotechnology Govt. Digvijay Autonomous P. G. College Raj-Nandgaon ( C. G. )

2. INTRODUCTION. NCBI. EMBL. DDBJ. CONCLUSION. REFERENSE. SYNOPSIS

3. In biology, Bioinformatics is an interdisciplinary field that develops and improves upon methods for storing, retrieving, organizing and analyzing biological data. A major activity in bioinformatics is to develop software tools to generate useful biological knowledge. Bioinformatics has become an important part of many areas of biology. Introduction

4. The National Center for Biotechnology Information ( NCBI ) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland and was founded in 1988 through legislation sponsored by Senator Claude Pepper. The NCBI houses a series of databases relevant to biotechnology and biomedicine. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for the biomedical literature. All these databases are available online through the Entrez search engine. National Center for Biotechnology Information

5. GenBank coordinates with individual laboratories and other sequence databases such as those of the European Molecular Biology Laboratory (EMBL) and the DNA Data Bank of Japan (DDBJ). Since 1992, NCBI has grown to provide other databases in addition to GenBank. NCBI provides Online Mendelian Inheritance in Man, the Molecular Modeling Database (3D protein structures), dbSNP (a database of single-nucleotide polymorphisms). The NCBI assigns a unique identifier (taxonomy ID number) to each species of organism.

6. Firstly the NCBI was type on the google and click search. Then click the National center for Biotechnology Information. NCBI home page was open. Example

7. N ucleotide database of Phosphoprotein P of Swine Para influenza virus 3.

8. The European Molecular Biology Laboratory ( EMBL ) is a molecular biology research institution supported by 20 European countries and Australia as associate member state. EMBL was created in 1974 and is an intergovernmental organization funded by public research money from its member states. Research at EMBL is conducted by approximately 85 independent groups covering the spectrum of molecular biology. The Laboratory operates from five sites: the main Laboratory in Heidelberg, and Outstations in Hinxton (the European Bioinformatics Institute (EBI)), Grenoble, Hamburg, and Monterotondo near Rome. European Molecular Biology Laboratory

9. The cornerstones of EMBL’s mission are: to perform basic research in molecular biology; to train scientists, students and visitors at all levels. EMBL’s international PhD Programme has a student body of about 170. The Laboratory also sponsors an active Science and Society programme. Many scientific breakthroughs have been made at EMBL, most notably the first systematic genetic analysis of embryonic development in the fruit fly by Christiane Nüsslein-Volhard and Eric Wieschaus, for which they were awarded the Nobel Prize for Medicine in 1995.

10. EMBL HOME PAGE.

11. EMBL-Bank (www.ebi.ac.uk/embl/), which began its life as the EMBL Data Library at the European Molecular Biology Laboratory’s Heidelberg headquarters in 1980, was the world’s first publicly available database of nucleotide sequence. History

12. The cornerstones of EMBL's mission are manifold. Basic research in molecular biology and molecular medicine is performed; scientists, students and visitors at all levels are trained; vital services to scientists in the member states are offered. New instruments and methods in the life sciences are developed; and there is an active engagement in technology transfer. Mission

13. Advanced training is one of EMBL's four core missions. Over the years, the Laboratory has established a number of training activities, of which the EMBL International PhD Programme (EIPP) is the flagship - it has a student body of about 200, and since 1997 has had the right to award its own degree. Other activities include the postdoctoral programme, including the EMBL Interdisciplinary Postdoctoral programme (EIPOD); the European Learning Laboratory for the Life Sciences (ELLS) for teacher training; and the Visitor Programme. Training

14. The European Bioinformatics Institute (EBI) is part of the European Molecular Biology Laboratory (EMBL) and is located on the Wellcome Trust Genome Campus in Hinxton near Cambridge (UK). The EBI grew out of EMBL’s pioneering work in providing public biological databases to the research community. It hosts some of the world’s most important collections of biological data, including DNA sequences (EMBL-Bank), protein sequences (UniProt), animal genomes (Ensembl), three-dimensional structures (the Macromolecular Structure Database) . The EBI hosts several research groups and its scientists continually develop new tools for the biocomputing community. About the EBI

15. DDBJ; DNA Data Bank of Japan is the sole nucleotide sequence data bank in Asia, which is officially certified to collect nucleotide sequences from researchers and to issue the internationally recognized accession number to data submitters. DDBJ

16. The DNA Data Bank of Japan (DDBJ) is a biological database that collects DNA sequences. It is located at the National Institute of Genetics (NIG) in the Shizuoka prefecture of Japan. It is also a member of the International Nucleotide Sequence Database Collaboration or INSDC. It exchanges its data with European Molecular Biology Laboratory at the European Bioinformatics Institute and with GenBank at the National Center for Biotechnology Information on a daily basis. Thus these three databanks contain the same data at any given time.

17. HOME PAGE OF DDBJ

18. DDBJ collects sequence data mainly from Japanese researchers, but of course accepts data and issue the accession number to researchers in any other countries. DDBJ is organized by NIG; National Institute of Genetics with endorsement of MEXT; Japanese Ministry of Education, Culture, Sports, Science and Technology. 99% of INSD data from Japanese researchers are submitted through DDBJ. The principal purpose of DDBJ operations is to improve the quality of INSD, as public domains.

19. The DNA Data Bank of Japan (DDBJ, http://www.ddbj.nig.ac.jp ) provides a nucleotide sequence archive database and accompanying database tools for sequence submission, entry retrieval and annotation analysis. The DDBJ collected and released 3 637 446 entries/2 272 231 889 bases between July 2009 and June 2010. DDBJ progress report

20. Since we exchange the collected data with EMBL-Bank/EBI; European Bioinformatics Institute and GenBank/NCBI; National Center for Biotechnology Information on a daily basis, the three data banks share virtually the same data at any given time.

21. The NCBI houses a series of databases relevant to biotechnology and biomedicine. Major databases include GenBank for DNA sequences. The EMBL Nucleotide Sequence Database (http://www.ebi.ac.uk/embl), maintained at the European Bioinformatics Institute (EBI) near Cambridge, UK, is a comprehensive collection of nucleotide sequences and annotation from available public sources. The DNA Data Bank of Japan (DDBJ, http://www.ddbj.nig.ac.jp ) provides a nucleotide sequence archive database and accompanying database tools for sequence submission, entry retrieval and annotation analysis. CONCLUION

22. http://www.ebi.ac.uk/embl/ http://www.ddbj.nig.ac.jp C.S.V. Murthy (2003) Bioinformatics : First Edition. S.C. Rastogi, Namita Mendiratta , Parag Rastogi (2003) Bioinformatics. REFERENCE