P athophysiology Altered GI motility Visceral hypersensitivity Post infectious reactivity Brain-gut interactions Alteration in fecal micro flora Carbohydrate malabsorption Intestinal inflammation Bacterial overgrowth Food sensitivity.
DIAGNOSIS Rome 1 criteria & Rome 2 in 1999 –required 12 Weeks -12 months. Rome 3 in 2006 –(IBS –C ,IBS-D ,IBS –M,IBS –U) stool frequency –clear Rome 4 –abdominal pain associated with defecation ,bloating /distension -6 months or 3 months Rome 5 –removed the discomfort, pain from 3 days to month.
DIET FOR IBS EATING HABITS Regular meal pattern Avoid skipping meals Leaving long gaps between eating or eating late at night Avoid large meal & take good time to eat ,to sit down to eat ,chew food thoroughly.
FAT Polyunsaturated fatty acids & their metabolites –beneficial in intestinal inflammation 40 – 50 g /day.
Dietary fiber Soluble fiber –psyllium –low fermentation 2-3 g /day is beneficial linseed -2tsp /day with fluid 150 ml for 3 months.(IBS-CONSTIPATION). Helps in relieves constipation ,abdomen pain & bloating. Fenugreek
PROBIOTICS Protect against pathogenic bacteria Also amplify the intestinal tight junctions & stability the permeability . Stimulates goblets cells to produce mucus to enhance the intestinal barrier function, normalized bowel movement & reduce visual hypersensitivity.
TURMERIC ANTIINFLAMMATORY -relieves abdominal pain . NEEM : ANTIBACTERIAL
GINGER Strengthen the muscles ,reduces the backflow of the stomach acid into esophagus & prevent acid reflux & indigestion.
FENNEL SEEDS Wound healing ,pain indigestion.
ALOE VERA Antibacterial & anti-inflammatory Acts in both constipation & diarrhea Pain flatulence 8weeks 30ml 2 times /day.
FLUID 1.5 -3 L /day (IBS-C) Improves stool frequency & decrease the need for laxatives in constipation.
ADD ARTICHOKE –antispasmodic CARMINT –relives pain PEPPERMINT – 3-4 times /daily for a month, reduces pain.