L.Tartaglia_20Jan23.pdf

Lawrence Tartaglia CV

1. Lawrence J. Tartaglia
111 Research Drive, Bethlehem PA, 18105 [phone] [email protected]

Training and Education
2014 – 2019 Postdoctoral Fellowship, Vaccinology and Vaccine Research
Harvard Medical School, Massachusetts
Advisor: Dr. Daniel Barouch
2013 PhD, Biochemistry and Molecular Biology
The University of Florida College of Medicine, Florida
Advisor: Dr. Mavis Agbandje-McKenna
2007 MS, Molecular Biology
Rutgers University, New Jersey
Advisor: Dr. Daniel Shain
2003 BA, Biology
Rutgers University, New Jersey
Professional Appointments
2022 – Present Teaching Assistant Professor
Lehigh University, Pennsylvania
2021 – 2022 Professor of Practice
Lehigh University, Pennsylvania
2020 – 2021 Visiting Assistant Professor
Lehigh University, Pennsylvania
2018 – 2019 Adjunct Professor
Emmanuel College, Massachusetts
Teaching Experience and Professional Development
Lehigh University, Instructor of Record
Classes: Semesters Taught (Summer/Su, Spring/Sp, Fall/Fa, Winter/Wi) Enrollment
Cellular and Molecular Su’22, Sp’22, Su’21, Sp’21, Su’20, Sp’20 250+ Students
Genetics Fa’22, Su’22, Fa’21, Fa’20 150+ Students
Biochemistry Lab Fa’22, Fa’21, Fa’20 35+ Students
Virology Sp’22, Sp’21 30 Students
Microbiology Lab Sp’20 25 Students
Special Topics in Biology Wi’23 10 Students
Emmanuel College, Instructor of Record
Cell and Molecular Lab Fa’19, Fa’18 25 Students
Organismic and Sp’19 25 Students
Evolutionary Biology Lab

2. Rutgers University, Teaching Assistant
Classes: Semesters Taught (Summer/Su, Spring/Sp, Fall/Fa, Winter/Wi) Enrollment
General Biology Lab I Su’05, Fa’05, Fa’04 25 Students
General Biology Lab II Su’06, Sp’05 25 Students
Anatomy & Physiology Fa’05 25 Students
Lab I
Anatomy & Physiology Sp’06, Sp’05 25 Students
Lab II

Other Teaching-Related Activities
Harvard Medical School
2014 – 2019 Developed and Organized the Lab Tech Research Club (LTRC) at Harvard
Medical School. An organizon that provided technicians with an opportunity
to presenter their research, practice public speaking, and participate in mock
Interview talks
University of Florida
2012 Designed and taught at 3-credit undergraduate seminar course for the
Student Science Training Program (SSTP). Topics included virus structural
biology and gene therapy applications
2008 Developed and presented a module on protein purification and structural
biology to high school teachers in a graduate program funded by Howard
Hughes Medical Institute
Teaching Professional Development
2022 Presenter, Large-Lecture Strategies, Lottery Card Instant Feedback and
Lecture Summaries for Clarity. Symposium for Teaching and Learning at
Lehigh University
2022 Presenter, as part of Lehigh’s Strategic Planning initiative, I was asked to
present my teaching practices in the classroom to the Education with Purpose
Group to show creative and innovative teaching methods
2020 Presenter, Synchronous Online Class Meetings: Designing and Delivering
Interactive Lessons in Zoom. Lehigh University Workshop on Online Learning
2019 Harvard Medical School Curriculum Fellows Program Education Workshop
Series – Teaching 101: Bringing Effective Teaching Practices to a Large
Classroom, Boston, Massachusetts
2019 Harvard Medical School Curriculum Fellows Program Education Workshop
Series – Using What’s Out There: Identifying and Evaluating Public
Resources for Teaching Science, Boston, Massachusetts
2019 Harvard Medical School Curriculum Fellows Program Education Workshop
Series – Finding Your Philosophy of Teaching (and writing it down), Boston,
Massachusetts

3. Teaching Certificate Program
2018 Certificate Program, Scientists Teaching Science Course offered through
the Harvard Medical School Postdoctoral Fellowship Program. Topics
included inquiry-based science, curriculum development, classroom
dynamics, cultural awareness and diversity, assessment of learning
environments, and active learning techniques
Lehigh University Service, Leadership, and Mentorship Positions
Service
2022 – Present Health Professions Advisory Committee Member
2022 Search Committee Member for Teaching Assistant Professor Position in
Organismal Biology in the Department of Biological Sciences
2022 Search Committee Member for Lab Manager Position in Department of
Biological Sciences
2022 Department Representative, CAS Majors/Minors Fair – 5 X 10 Event –
Creative Curiosity for First-Year Students
2021 – Present Undergraduate Committee Member in Department of Biological Sciences
Leadership
2022 – Present Faculty Advisory and Co-Founder of Operation Smile at Lehigh University.
A non-profit chapter at Lehigh University that raises awareness
for genetic-related diseases such as cleft palette
2021 – Present Faculty Advisor and Co-Founder of the Minority Association of Pre-
Medical Students at Lehigh University – An organiz that provides
students who identify as a minority with access to pre-med/pre-health related
information, events, and spaces for collaboration
2021 – Present Faculty Advisor and Co-Founder of the Minority Association of the
Scientific Journal Club at Lehigh University – An organization that creates
a platform for students to explore their scientific interests, develop their public
speaking skills, enhance their manuscript reading and comprehension, as well
as other activities related to career development and advancement
Mentorship
2023 Apprentice Teacher Mentor, Nathanael Borger
2023 Apprentice Teacher Mentor, Jason Yeung
2022 – Present Dissertation Committee Member, Nusaibah Alqasawah
2022 Invited Keynote Speaker, Academic Awards Banquet for Alpha Gamma
Delta and Phi Delta Theta Greek Organiz , Hotel Bethlehem
2022 Science Judge, Global Social Impact Fellowship Program Q&A
Presentations (two nights)
2022 Faculty Representative Invitee, Global Citizenship Program Breakfast Think
Thank, participated in deep discussions with the senior cohort of students
regarding global issues

4. 2022 Reviewer, Science is Art Competition at Lehigh University
2022 Committee Member, Jing Guo, Honor’s Thesis
2022 Invited Faculty Presenter, 5 X 10 Symposium for incoming student at
Lehigh University. So, you want to use your STEM degree as a springboard
to professional school?
2022 – 2023 Eckardt’s Scholar Mentor, Heidi Shen
2022 Educational Research Mentor, Nathanael Borger
2021 – Present Covid-19 Expert Committee Member at Lehigh University
2021 NavigateLU Faculty Collaborator – An initiative to engage and mentor
assigned first-year students over a 10-week period
2021 Invited Faculty Presenter, 5 X 10 Symposium for incoming student at
Lehigh University. So, you want to use your STEM degree as a springboard
to professional school?
2021 Invited Faculty Presenter, Want to get Involved in Research? Scientific
Journal Club
2021 Invited Faculty Presenter, How to Read a Scientific Manuscript. Scientific
Journal Club
2020 Invited Faculty Presenter, 5 X 10 Symposium for incoming student at
Lehigh University. Extremophiles, Viruses, and Medicine…Oh My!
University Leadership Positions
2021 – Present Mentor, University of Florida College of Medicine Mentor Program
as part of the Alumni Ambassador Network
2016 – 2017 Vice President of Harvard Medical Postdoctoral Association
2015 – 2016 Outreach Chair of Harvard Medical Postdoctoral Association
2014 – 2015 Career Development Committee Member and Governing Board Member
of Harvard Medical Postdoctoral Association
2011 – 2012 Graduate Student Representative of the Biochemistry and Molecular
Biology Department at the University of Florida
2001 Team Captain, Rutgers University Cross Country
Awards
2017 Early-Stage Investigator Award, HIV Vaccine Trials Network Conference
2017 Outstanding Poster Presentation Award, American Society of Gene and
Cell Therapy
2012 Travel Award, UF Interdisciplinary Program in Biomedical Sciences,
Biochemistry and Molecular Biology Concentration
2011 BIAcore Inspiration X100 Contest Award Winner

2009 Travel Award, UF Interdisciplinary Program in Biomedical Sciences,

5. Biochemistry and Molecular Biology Concentration
2009 Travel Award, American Society for Virology Grant
2008 Travel Award, UF Interdisciplinary Program in Biomedical Sciences,
Biochemistry and Molecular Biology Concentration
2005 Best Graduate Student Presentation Award, New Jersey Academy of
Sciences
2005 Best Graduate Student Presentation in Biochemistry Award, New
Jersey Academy of Sciences
2005 Best Overall Graduate Presentation Award, American Association for the
Advancement of Science (AAAS)
2005 National Dean’s List Inductee
2000 Rutgers University Cross Country Most Valuable Player Award
Science and Diversity Outreach
2022 Mock Class Teacher, Diversity Achievers Program at Lehigh University.
Taught a mock class for high school students from diverse backgrounds
around the world
2022 Organizer, Women in STEM Day at Southern Lehigh High School.
Recruited a group of female scientists from Lehigh University to speak with
and share their experiences as a woman in science at a local high school
2022 Organizer, Research Day at Southern Lehigh High School. Recruited a
group of undergraduate students from Lehigh University to speak with
and present their research work to students at a local high school
2019 Scientific Panelist at Science Career Night at Brooke High School in
Massachusetts. Engaged a diverse group of students and fielded questions
questions about a career in the sciences
2019 Science Judge at the 70
th
Annual Massachusetts State High School
Science and Engineer Fair
2018 Science Judge at the 69
th
Annual Massachusetts State High School
Science and Engineer Fair
2017 Science Judge at the 68
th
Annual Massachusetts State High School
Science and Engineer Fair
2016 Science Judge at the 67
th
Annual Massachusetts State High School
Science and Engineer Fair
Research Mentees
2019 Gabriel Dagotto, PhD candidate, Harvard Medical School
2017 – 2018 Siddhant Gupte, Master’s Thesis, Harvard Medical School
2016 – 2017 Kevin Pastores, Master’s Thesis, Boston University
2016 Michael Boyd, Master’s Thesis, Northeastern University
2016 Sebastien Trott, Undergraduate Summer Student, McGill University

6. 2011 - 2013 Alex Plattner, Undergraduate Student, University of Florida
2010 Roman Kazakov, Undergraduate Student, University of Florida
2008 - 2010 Andrew Woodhouse, Undergraduate Student, University of Florida
Conferences, Workshops, and/or Courses Attended
2021 Student National Medical Association (SNMA) Region VIII Leadership
Conference: “Excellence in Medicine: Balancing Leadership, Academics and
Life”. Minority Association for Premedical Students. October 16, 2021.
Geisinger Commonwealth School of Medicine
2018 I4C Collaboratory SAB Meeting, Boston, Massachusetts
2017 HIV Vaccine Trials Network (HVTN) – Translational Early Stage Investigator
Workshop. Washington, District of Columbia
2016 Discovery On Target Gene Therapy Workshop. Boston, Massachusetts.
2014 Healthcare Innovation and Commercialization (HIC) 12-week course.
Harvard Medical School, Boston, Massachusetts
2010 NCMI Workshop on Single Particle Reconstruction, Validation and Analysis.
Baylor College of Medicine, Houston, Texas
2009 GE Healthcare Protein Expertise Tour, Gainesville, Florida
2009 Cryo-Electron Microscopy Symposium, Tallahassee, Florida
Memberships
2020 – Present National Science Teaching Association
2017 American Society of Gene and Cell Therapy
2015 American Association of Immunologists
2010 – 2012 FASEB Virus Structure and Assembly
2008 – 2009 American Society for Virology
In the Media
2021 Interviewee, WFMZ News Television Story about Covid-19
2021 Interviewee, Colleging Hear My Story Podcast: The Science Behind Covid
Publications
1. Tartaglia, L.J., Gupte, S., Pastores, K.C., Trott, S., Abbink, P., Mercado, N.B., Zhenfeng,
L., Liu, P., Borducchi, E.N., Chandrashekar, A., Bondzie, E.A., Hamz
Barouch, D.H. Differential outcomes following optimization of Simian-Human
Immunodeficiency Viruses from Clades AE, B, and C. Journal of Virology. May 2020 doi:
10.1128/JVI.01860-19
2. Tartaglia L.J., Badamchi-Zadeh, A., Abbink, P., Blass, E., Aid, M., Gebre, M. S., Li, Z.,
Pastores, K.C., Trott, S., Gupte, S., Larocca, R.A., Barouch, D.H. Alpha-defensin 5
differentially modulates adenovirus vaccine vectors from different serotypes in vivo. Plos
Pathogens. December 2019. doi: 10.1371/journal.ppat.1008180

7. 3. Badamchi-Zadeh
,
A., Tartaglia

L.J., Abbink
,
P., Bricault
,
C.A., Liu
,
P., Boyd,

M., Kirilova,
M., Mercado, N., Nanayakkara, O.S., Vrbanac, V.D., Larocca,

R.A., Seaman, M.S.,
Barouch, D.H. Therapeutic efficacy of vectored PGT121 gene delivery in HIV-infected
humanized mice. Journal of Virology. January 2018 doi:10.1128/JVI.01925-17
4. Abbink P., Kirilova, M., Boyd, M., Mercado, N., Zhenfeng, L., Nityanandam, R.,
Nanayakkara, O., Peterson, O., Larocca, R.A., Aid, M., Tartaglia, L.J., Mutetwa, T., Blass,
E., Jetton, D., Maxfield, L., Borducchi, E., Badamchi-Zadeh, A., Handley, S., Zhao, G.,
Virgin, H., Havenga, M., and Barouch, D.H. Rapid Cloning of Novel Rhesus Adenoviral
Vaccine Vectors. Journal of Virology. January 2018 doi:10.1128/JVI.01924-17
5. Julg, B., Liu, P., Wagh, K., Fischer, W.M., Abbink, P., Mercado, N.B., Whitney, J.B.,
Nkolola, J.P., McMahan, K., Tartaglia, L.J., Borducchi, E.N., Khatiwada, S., Kamath, M.,
LeSuer, J.A., Seaman, M.S., Schmidt, S.D., Mascola, J.R., Burton, D.R., Korber, B.T.,
Barouch, D.H. Protection against a mixed SHIV challenge by a broadly neutralizing
antibody cocktail. Science Translational Medicine. September 2017. 9 (408)e4235
6. Xu, L., Pegu, A., Rao, E., Doria-Rose, N.

, Beninga, J. , McKee, K., Lord, D.M., Wei, R.R.,
Deng, G., Louder, M., Schmidt, S.S., Mankoff, Z., Wu, L., Asokan, M., Beil, C., Lange,C.,
Leuschner, W.D., Kruip, J., Sendak, R., Do Kwon, Y., Zhou, T., Chen, X., Bailer, R.B.,
Wang, K., Choe, M., Tartaglia, L.J., Barouch, D.J., O’Dell, S., Todd, J., Burton, D.R.,
Roederer, M., Connors, M., Koup, R.A., Kwong, P.D., Yang, Z., Mascola, J.R., Nabel,
G.J. Trispecific antibodies mediate highly potent and broad neutraliz and
confer expanded protection against SHIV infection in macaques. Science. October 2017
358 (6359):85-90
7. Julg, B*., Tartaglia, L.J.*, Brandon F. Keele, B.F., Wagh, K., Amarendra Pegu, A., Devin
Sok, D., Abbink, P., Schmidt, S.D., Wang, K., Chen, X., Joyce, M.G., Georgiev, I.S., Choe,
M., Kwong, P.D., Doria-Rose, N.A., Le, K., Louder, M.K., Bailer, R.T.
5
, Moore, P.L., Korber,
B., Seaman, M.S., Abdool Karim, S.S., Morris, L., Koup, R.A., Mascola, J.R., Burton,
D.R., Barouch, D.H. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex
confer protection against a clade C SHIV challenge. (* These authors contributed
equally). Science Translational Medicine. September 2017. 9 (406)e1321
8. Aid M., Abbink,P., Larocca, R.A., Boyd, M., Nityanandam, R., Nanayakkara, O., Martinot,
A.J., Moseley, E.T., Blass, E., Borducchi, E.N., Chandrashekar, A., Brinkman, A.L., Molloy,
K., Jetton, D., Tartaglia, L.J., Liu, J., Best, K., Perelson, A.S., De La Barrera, R.A., Lewis,
M.G., Barouch, D.H. Zika virus persistence in the central nervous system and lymph nodes
of rhesus monkeys. Cell. May 2017. 169(4): 610-620
9. Tartaglia,L.J, Chang, H-W., Lee, B.C., Abbink, P., Ng’ang’a, D., Boyd M., Lavine, C.L.,
Lim, S-Y, Sanisetty, S., Lavine, C.L., Whitney, J.B., Seaman, M.S., Robb, M.L., Kim, J.H.,
Michael, N.L., Barouch, D.H. Production of mucosally transmissible SHIV challenge stocks
from HIV-1 circulating recombinant form 01_AE env sequences. Plos Pathogens.
February 2016. 12:e1005431
10. Chang H-W, Tartaglia, L.J., Whitney, J.B., Sanisetty, S., Lavine, C. L., Seaman, M. S.,
Barouch, D.H. Generation and evaluation of clade c transmitted/founder simian-human
immunodeficiency virus challenge stocks. Journal of Virology. February 2015.
89:1965-1974
11. Tartaglia, L.J., Bennett, A., Plattner, A.S., Ling, C., Muzyczka, N., Srivastava, A.,
Agbandje-McKenna, M. Molecular cloning, overexpression, and an efficient one-step
purification of α5β1 integrin. Protein Expression and Purification. November, 2013
92:21-28

8. 12. Tartaglia, L.J., Bennett, A., Woodhouse, A.G., Aydemir, F., Muzyczka, N., Agbandje-
McKenna, M. Construction, expression, and purification of recombinant αVβ5 integrin.
Protein Expression and Purification. June 2013. 89:225-231
13. Judd, J., Wei, F., Nguyen, P.Q., Tartaglia, L.J., Agbandje-McKenna, M., Silberg, J.J., Suh,
J. Random insertion of mcherry into VP3 domain of adeno-associated virus yields
fluorescent capsids with no loss of infectivity. Molecular Therapy Nucleic Acids. Nov 2
2012. 13:e54
14. Genis, C., Sippel, K.H., Case, N., Cao, W., Avvaru, B.S., Tartaglia, L.J, Govindasamy, L.,
Tu, C., Agbandje-McKenna, M., Silverman, D.N., Rosser, C.J., McKenna, R. Design of a
carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer
properties. Biochemistry. Feb 2009. 48:1322-1331
15. Tartaglia, L.J., Shain, D.H. Cold-adapted tubulins in the glacier ice worm,
Mesenchytraeus solifugus. Gene. Nov 2008. 423: 135-141
Invited Oral Presentations
Harvard University Center for Aids Researcher (CFAR) Retrovirology Club
2015 Tartaglia, L.J. Identification and construction of novel rhesus adeno-associated
viruses for gene delivery AND generation of clade AE simian-human
immunodeficiency virus challenge stocks. Cambridge, Massachusetts
Ragon Institute of MGH, MIT, and Harvard Seminar Series
2014 Tartaglia, L.J. Identification and construction of novel rhesus adeno-associated
viruses for gene delivery AND adenovirus and alpha defensin interactions.
Cambridge, Massachusetts
Cambridge Healthtech’s Institute 13
th
Annual PepTalk
2010 Tartaglia, L.J., Bennett, A., Plattner, A., Ling, C., Muzyczka, N., Srivastava, A.,
Agbandje-McKenna, M. Molecular cloning, overexpression, and an efficient one-
step purification of αVβ5 and α5β1 integrin. Engineering Genes, Vectors,
Constructs, and Clones Meeting. Palm Springs, California
GE Healthcare Life Sciences Label-Free Analysis Seminar
2010 Tartaglia, L.J., Tseng, Y., Gurda, B., Agbandje-McKenna, M. Virus antibody
interactions. Gainesville, Florida
Oral Presentations
New Jersey Academy of Sciences
2006 Tartaglia, L.J. Cold-adapted microtubules in the ice worm, Mesenchytraeus
Solifugus
2004 Tartaglia, L.J. Tubulin subunits in the ice worm, Mesenchytraeus solifugus
2004 Tartaglia, L.J. Tubulin assembly in cold-adapted organisms
Poster Presentations
American Society of Gene and Cell Therapy

9. 2017 Tartaglia,L.J., Badamchi-Zadeh, A., Abbink, P., Pastores, K, Barouch, D.H.
Alpha-defensin 5 augments immunomodulatory responses elicited by an
adenovirus 25 vaccine delivery vector in the context of a Listeria challenge model.
Washington, District of Columbia
33
rd
Annual Symposium on Nonhuman Primate Models for AIDS
2015 Tartaglia,L.J., Chang, H-W., Lee, B.C., Abbink, P., Ng’ang’a, D., Boyd M., Lavine,
C.L., Lim, S-Y, Sanisetty, S., Lavine, C.L., Whitney, J.B., Seaman, M.S., Robb,
M.L., Kim, J.H., Michael, N.L., Barouch, D.H. Production of mucosally
transmissible SHIV challenge stocks from HIV-1 circulating recombinant form
01_AE env sequences. Monterey, California.
American Association of Immunologists
2015 Tartaglia,L.J., Chang, H-W., Lee, B.C., Abbink, P., Ng’ang’a, D.,Boyd M., Lavine,
C.L., Lim, S-Y, Sanisetty, S., Lavine, C.L., Whitney, J.B., Seaman,M.S., Robb,
M.L., Kim, J.H., Michael, N.L., Barouch, D.H. Generation and evaluation of simian-
human immunodeficiency virus subtype AE challenge stocks. New Orleans,
Louisiana
University of Florida College of Medicine Celebration Research Day
2013 Tartaglia, L.J., Bennett, A., Plattner, A.S., Muzyczka, N., Agbandje-McKenna, M.
Mapping the binding site for the α5β1 integrin co-receptor on the adeno-associated
virus serotype 2 capsid. Gainesville, Florida
University of Florida Cryo-EM Workshop
2013 Tartaglia, L.J., Bennett, A., Plattner, A.S., Muzyczka, N., Agbandje-McKenna, M.
Mapping the binding site for the α5β1 integrin co-receptor on the adeno-associated
virus serotype 2 capsid. Gainesville, Florida
FASEB Virus Structure and Assembly
2012 Tartaglia, L.J., Bennett, A., Woodhouse, A., Muzyczka, N., Agbandje-McKenna, M.
The interaction and characterization of adeno-associated virus serotype 2 with its
integrin co-receptors. Federation of American Societies for Experimental Biology
(FASEB), Virus Structure and Assembly. Saxtons River, Vermont
FASEB Virus Structure and Assembly
2010 Tartaglia, L.J., Bennett, A., Muzyczka, N., Agbandje-McKenna, M. Adeno-
associated virus serotype 2 and its integrin co-receptors. Federation of American
Societies for Experimental Biology (FASEB), Virus Structure and Assembly. Saxtons
River, Vermont.
American Society for Virology
2009 Tartaglia, L.J., Bennett, A., Aydemir, F., Muzyczka, N., Agbandje-McKenna, M. The
characterization of the interaction of adeno-associated virus serotype 2 (AAV2) with
its integrin co-receptors for cellular internaliz
th
annual meeting of the
American Society for Virology, Vancouver, British Columbia.