Oestrogen Hormones.pptx

concept based on oestrogen harmones

1. APOLLO college of pharmacy Anjora durg (cg) PRESENTED BY – MR. SAURABH SAHU MIS.SUSMITA SHIKARI MR.GAIND LAL MR.TAMESHWER GUIDED BY – Mr.HARI PRASAD SONWANI Pharmacology (Oestrogen Hormones)

2. Adolf Butenandt & Edward Adlerbert Dost isolated & Determined the structure of estrogen

3. FEMALE SEX HORMONES(OESTROGEN) ● also known as female sex hormone ●It is the responsible for the devlopment and regulation of the female reproductive system ●there are three major endogenous estrogen in female

4. 1) Estron 2) Estradiol 3) Estriol ◆ semisynthesis • Ethinylestradiol •Mestranol • Quniestrol ◆natural oestrogens ● Estradiol ● Estrone ● Estriol • Diethylstibestrol ◆Synthetic estrogen

5. ◆Non steroidal agent with estrogen activity ● cholrotrianisene

6. Classification

7. Therapeutic Aplicastions -: 1)Men paidal syndrome 2)Ovarian dysgenesis 3)Primary amenorrhoea 4) To treat breast Cancer

8. 5) To treat functional uterine bleeding and endometriosis 6) To treat dysmenorrhoea 7) As An oral contraceptive with progesterone

9. Side Effects ● Nausea and vomiting ● Brest tenderness ●Salt and water retention causes weight gain cardiac failure

10. Function- : Estrogen enables the following organs to function: Ovaries:  Estrogen   helps stimulate  the growth of the egg follicle. Vagina: In the vagina, estrogen   maintains the thickness Trusted Source  of the vaginal wall and promotes lubrication. Uterus:  Estrogen enhances and maintains the mucous membrane that lines the uterus. It also regulates the flow and thickness of uterine mucus secretions. Breasts: The body uses estrogen in the formation of breast tissue. This hormone also helps stop the flow of milk after weaning.

11. Estrogen levels vary among individuals. They also fluctuate during the menstrual cycle and over a female’s lifetime Factors that can affect estrogen levels include: pregnancy, the end of pregnancy, and breastfeeding puberty menopause older age overweight and  obesity extreme dieting or  anorexia nervosa strenuous exercise or training

12. high blood pressure diabetes primary ovarian

13. Food sources of estrogen cruciferous vegetables soy and some foods containing soy protein berries seeds and grains nuts fruit wine

14. REFERENCE-: Tripathi.k.d (2018) EsseNtial Of medical pharmacology www.SlideshArE.net www.medinewstoday .com

15. THANK YOU