Ototoxicity

BSC NURSING III YEAR

1. ototoxicity Mr. Manikandan.T , RN., RM., M.Sc (N)., D.C.A .,( Ph.D ) Assistant Professor, Dept. of Medical Surgical Nursing, VMCON, Puducherry .

2. DEFINITION Ear poisoning due to exposure to drugs or chemicals which damage the inner ear and vestibulo cochlear nerve

3. CAUSES Quinine and salicylates : tinnitus and hearing loss may occur due to effect of this drugs Aminoglycosides : streptomycin – balance& hearing Loop diuretics: permanent sensori neural hearing loss Antiepiletics : vestibular disorder Betablockers : deafness Chemicals: mercury, CO, Carbondisulphide

4. CLINICAL FEATURES Tinnitus Imbalance Vertigo Hearing loss

5. DIAGNOSIS H/C P/E Electrocochleography  (abbreviated ECochG or ECOG) is a technique of recording electrical potentials generated in the inner ear and auditory nerve in response to sound stimulation, using an electrode placed in the ear canal or tympanic membrane . Electronystagmography Auditory brainstem response

6. MANAGEMENT Limit use of ototoxic drugs Periodic ophthalmic/ audiometric examination Hearing aids for hearing loss vestibular exercises Treat the underlying causes