Research synthesis:
What, why and how?
Dr Ernestina Coast
Research synthesis
What is known from what has been done?
NOT
What has been done?
Many different types of research
synthesis
Systematic review
Meta-ethnography (qualitative)
Meta-analysis (quantitative)
What is research synthesis?
A comprehensive review that looks for, and
evaluates, existing research evidence.
NOT
“Traditional” literature review
Characteristics
Rigorous methods
A “scientific” methodology
Replicable / accountable / updateable
Minimise bias and error
Answer to focussed question(s)
Why useful?
Balanced inference on best available
evidence
NOT
Description of everything on the subject
Quantitative systematic reviews
Well-established
Well-funded
National and international collaborations
Associated with RCTs
Associated with intervention research i.e.: “What
works”?
A cornerstone of evidence-based practice and policy
Research synthesis: 5 steps
1.Decide what question(s) you are trying to
answer
2.Identify a protocol
What evidence are you prepared to include?
3.Find all of the relevant evidence
Data mapping an output in its own right?
Identify major knowledge gaps
4.Appraise the quality of the evidence
5.Decide what the evidence means
Recent UK example: DiCenso et al,
2003
Objective: To review the effectiveness
of primary prevention strategies aimed at
delaying sexual intercourse, improving
use of birth control, and reducing
incidence of unintended pregnancy in
adolescents.
Study selection: 26 trials described in
22 published and unpublished reports that
randomised adolescents to an intervention or a
control group (alternate intervention or
nothing).
Data extraction: Two independent reviewers
assessed methodological quality and abstracted
data.
Qualitative research as postscript
“insidious discrimination”
Via
“institutionalised quantitativism”
Booth (2001)
Meta-ethnography
Education
Nursing
Are qualitative research (data) appropriate for
research synthesis?
Unlikely to use RCT design
Less likely to have been used as methodology for
intervention research
Where to search for evidence?
“qualitative research clearly has a role…but it is
unclear how systematic reviews of qualitative
research can contribute…..”
5 steps revisited: qualitative evidence
1.Decide what question you are trying to answer
2.Identify a protocol
What evidence are you prepared to include?
3.Find all of the relevant evidence
Likely to involve lots of hand searching
Language
Qualitative research tends to be less well indexed than
quantitative research
4.Appraise the quality of the evidence
Different or same as for quantitative evidence?
5.Decide what the evidence means
Uniqueness of the ethnographic method is
reflexivity
Richness of insight: an emphasis on
contradictory cases
Existence of multiple views/ perspectives
Alternative interpretations
Potentially competing explanations
Research synthesis very limited in forms of
evidence that are incorporated
Need robust ways of incorporating
qualitative evidence into research synthesis
A more holistic view of what constitutes
“evidence”
Alternatively….
Policy issues not the business of academic
researchers
Try writing that on a funding proposal……
Role of an academic researcher is not to seek
common ground
Post-modernity
Absolute evidence does not exist
Synthesis of qualitative research
Bayesian approaches?
Use qualitative evidence to identify variables for
synthesis then attach weights to strength of
quantitative evidence associated with these variables
A proliferation of checklists
Meta-ethnography a sign of
“methodological maturity”?
Not a call for uncritical translation of
quantitative research synthesis approaches
Stand-alone or integrated
Quantitative supremacy?