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1. Welcome to CNE
Nepaljung Military Hospital

2. SNAKE BITE IN
NEPAL
T/Sub UttarikaBudhathoki

3. CONTENTS:
Introduction of snake bite in Nepal
Types of Snakes in Nepal
Introduction to non-poisonous and poisonous snake
Identification of non-poisonous and poisonous snake
Sign and symptoms of poisonous and non-poisonous snake
bite
Diagnosis and First aid management
Antivenom treatment
Nursing Care

4. Introduction
Snake bite is a life threatening and time
limiting medical emergency
89 species have been identified in Nepal
17 species of snake are found to be venomous
In Nepal, WHO estimates that 20,000 people
are bitten by snakes each year, resulting in
over 1000 deaths
Snake bite commonly occurs in Terai districts
during summer and monsoon

5. Snake of medical Importance
Poisonous
Non-Poisonous
●Ptyasmucosa–Rat Snake
●Checkered keelback-Paani Sarpa
●Coelognathushelena–Common
Trinket Snake( Himalayan sarpa)
●Amphiesmastolatum–Buff-striped
Keelback
●Dendrelaphistristis–Bronzeback
Tree Snake
Common Name Type of Venom
Common Krait Neurotoxic
Banded Krait Neurotoxic
Russell’s Viper Hematotoxic
Green Pit Viper Hematotoxic(mild)
Himalayan Pit ViperHematotoxic(mild)

6. Non-Poisonous
snake
They are harmless
Friends of farmers-helps to control pests like
rodents and snake
Usually not aggressive unless provoked

7. Features
No fangs or venom glands,have small teeth
instead
Rounded head(not triangular),no head neck
distinction
Round pupils
Double row of scales on the underside of tail

8. COMMON NON-POISONOUS SNAKES

9. Indian Rat snake(Dhamin)
●Seen in village and farmland
●Eats frogs and small birds
●Often mistaken for cobra due to its size and holding
behavior

10. Checkered keelback(Paani Sarpa)
●Common near rivers, ponds and rice field
●feeds on fish and frogs

11. Himalayan Trinket( Chameli Sarpa)
●Slender
●hunts, rodents and birds
●found in forests and near human settlements

12. Green keelback(hariyo dhamin)
●Found in forests and hilly area
●feeds on frogs and insects
●Shy and harmless

13. Indian python(अिजङगर)
•Non-poisonous
•found in terai region, forests grasslands
•slow moving ,shy and non-aggressive
•kills prey by constriction

14. Poisonous Snake
●Common venomous snakes include:
•Common Krait (Bungarus caeruleus)
•Indian Cobra (Naja naja)
•Russell’s Viper (Daboia russelii)
●These snakes cause neurotoxic or hematotoxic effects, which can
be fatal if untreated.

15. Common cobra(Goman, nag)
•Found in Terai region
•active during early morning and evening hours,
•warm and humid months (May to October)

16. Krait
Common Krait(seto kalo chure sarpa) Banded krait(laxmi sanp,pahelo kalo chure sarp)
•found mainly in the Terai region
•It is nocturnal and highly active at night.

17. Viperadae
Russel’s viper
Pit viper(Haryou sarpa)
•Found in terai and lower hills
•They are active during the day and are often found in fields, grasslands.

18. Sign and symptoms of Non-
poisonous snake bite
◦Local pain
◦Swelling
◦Redness
◦Puncture/scratch marks
◦No neurotoxic or hemotoxic symptoms
◦Possible mild infection if untreated

19. Signs and Symptoms of Poisonous
snake

20. General
Manifestations
Nausea,
Vomiting
Pain abdomen
Malaise
Weakness
Drowsiness
Anxiety
Excessive salivation, etc.

21. Localeffects
Cobra
•Swelling and local pain
with or without erythema
or discoloration at the bite
site.
•Blistering, bullae
formation and local
necrosis are also common.
•If it is infected, there may
be abscess formation.
Krait
•Usually do not cause signs
of local envenoming and
can be virtually painless.
Viper
•Swelling, blistering,
bleeding, and necrosis at
the bite site, sometimes
extending to the whole
limb.
•Persistent bleeding from
fang marks, wounds or
any injured parts of the
body.
•Swelling or tenderness of
regional lymph node.

22. SystemicManifestations
Hematotoxic
•Bleeding may from
venipuncture site, gums,
•Epistaxis
•Hemoptysis
•Melena, rectal bleeding
•Hematuria, bleeding
from vagina
•Subconjunctival
hemorrhage
•Petechiae, purpura,
ecchymosis
Neurotoxic
•Ptosis
•Ophthalmoplegia
•Pupillary dilatation- often
non- responsive to light
•Inability (or limitation) to
open mouth
•Numbness around lips
and mouths
Neurotoxic
•Tongue extrusion-
inability to protrude the
tongue beyond incisors
teeth.
•Inability to swallow
•Broken neck sign
•Skeletal muscle
weakness.
•Loss of gag reflex
•Paradoxical breathing
•Respiratory failure

24. Diagnosis
•No investigations available that can
help diagnose the neurotoxic
manifestations
Neurotoxic

25. Diagnosis
Hematotoxic
•20-minutewholebloodclottingtest(20WBCT)
•Bleedingtime(BT)andclottingtime(CT)
•ProthrombintimeandInternationalnormalizationratio
(INR)
•fibrinogen,d-dimer
•Kidneyfunctiontestandliverfunctiontest
•Completebloodcount,bloodgroup
•UrineforRBCsor myoglobin
•Creatinekinase

26. MANAGEMENT

27. TREATMENT OF SNAKEBITE
ENVENOMING
First aid treatment and transport to the hospital
Rapid clinical assessment and resuscitation
Antivenom treatment
Supportive/ancillary treatment
Treatment of the bitten part

28. RecommendedFirstaidTreatment
REASSURANCE
•Mostarenonvenomoussnakes.Manyaredrybites.
•Treatablecondition.
IMMOBILIZAT
ION
•Withasplintorsling.
•Pressureimmobilizationincaseofpurelyneurotoxicsnakebite
•Pressurepadimmobilization
•Removerings,jewelries,tightfittingsandclothing
RAPID
TRANSPORT
•Todecreasethedelayinaccessingtheemergencycareandreducemortility

29. Rapid clinical assessment and resuscitation
A – Airway
•Check if the airway is clear and look for obstruction (especially in neurotoxic envenoming).
•Provide oxygen immediately using nasal prongs, catheter, or mask.
•Prepare for intubation if respiratory failure is present.
B – Breathing
•Assess the patient’s breathing rate and effort.
•Provide bag-mask ventilation if breathing is inadequate.
C – Circulation
•Monitor blood pressure and pulse.
•In cases like Russell’s viper bite, treat shock with:
•IV fluids (normal saline) ,Blood transfusion if bleeding.

30. Cont..
D – Disability (Neurological status)
•Assess level of consciousness and neurological function.
•Look for signs of neurotoxicity: ptosis, paralysis, respiratory depression.
•Reassess regularly using a neurological scoring system if available.
E – Exposure & Environment
•Fully expose patient to examine bite site and swelling.
•Prevent hypothermia during examination.
•Observe for signs of systemic envenoming (bleeding, swelling, etc.)

31. What to do and what not to do in snake bite
What To Do
•Reassure the patient
•Nil per mouth
•Remove shoes, rings, watches,
jewelleries,tight clothing at bitten area
•Leave blisters undisturbed
•Shift the victim to the nearest hospital
ASAP
•Monitor closely and inform doctor
about sign and symptoms that were
present during transport
What Not To Do
•Cutting and sucking of bite site
•Application of various
chemicals, local remedies, cow
dung
•Application of Tight Tourniquets
•Do not try to kill or capture the
snake(however if already killed
then should be taken to hospital
for identification)

32. ANTIVENOM TREATMENT

33. Antivenom in Nepal
Imported from India and is Polyvalent
Anti-Snake Venom (ASV)
Effective against the four common
species of snakes;
Russell's Viper (Daboia russelii),
Common Cobra (Naja naja),
Common Krait (Bungarus caeruleus) and
Saw Scaled Viper (Echis carinatus).

34. Indication Of
Antivenom
Administration
Signs/Symptoms
Evidence of Neurotoxicity
- Ptosis - External
ophthalmoplegia - Broken neck
sign - Respiratory difficulty
Evidence of Coagulopathy
-Positive 20-minute Whole
Blood Clotting Test (20 WBCT)
- Visible spontaneous systemic
bleeding (e.g., bleeding gums)
- Rapid extension of local
swelling (more than half of
limb, not due to pit viper bite
or tight tourniquet)
Evidence of Cardiovascular
Collapse
- Shock and hypotension
(especially in Russell’s viper bite)
Evidence of Acute Kidney
Injury (AKI)
- Low urine output ,dearranged
RFT

35. Route of
Administration
Route
Patient
Type
Dilution
Administration
Rate
Notes
IV InfusionAdult
5–10 ml/kg
body weight (≈
250–500 ml) of
isotonic saline
or glucose
Infusion at 2
ml/min
Most
commonly
used route
Children
3–5 ml/kg body
weight of
isotonic saline
or dextrose
water
Infusion at 2
ml/min
IV InjectionAdult/Child
Reconstituted
antivenom (no
specific dilution
mentioned)
Slow IV at 2
ml/min
Rarely
practiced
Each vial is diluted with 10 ml. of sterile water as supplied with
the antivenom

36. Antivenom Dose
Type of Envenoming Dose Dilution & AdministrationRepeat Dose Criteria
Neurotoxic Envenoming
Initial Dose: 10 vials (100
ml)
Dilute with 100–400 ml of
dextrose water or saline;
IV infusion at 2 ml/min
(over 40–60 min @ 60–70
drops/min)
Only if neurological signs
deteriorate (not just
persist); administer 5 vials
(50 ml) as IV push @ 2
ml/min
Hematotoxic Envenoming
(e.g., Russell’s viper)
Initial Dose: Same as
neurotoxic envenoming
(10 vials)
Same dilution and IV
infusion method
Repeat every 6 hours if
20WBCT or other
coagulation tests remain
abnormal; administer 5
vials (50 ml) as IV push @
2 ml/min
Pediatric Dose Same as adult dose
Snakes inject equal
venom regardless of age
Same as adults

37. Response to treatment
◦General symptoms may disappear vary quickly.
◦Spontaneous systemic bleeding usually stops within 15-30 min.
◦Blood pressure may increase within 30-60 min.
◦Neurotoxicity may improve as early as 30 min.
◦Blood coagulability is usually restored in 3-9 hrs.

38. Reasons for
failure to
respond to
antivenom
Excessive delay in administration of
antivenom
Patient with established respiratory failure.
If antivenom administered does not contain
neutralizing antibodies against
the venom of biting species.
Insufficient dose of antivenom.
Inactive or poor quality antivenom.

39. Supportive
care
Fluid resuscitation
Oxygen
Intubation and ventilation
Dialysis

40. When
antivenom is
not available
Neostigmine: 0.5 mg SC/IV/IM (0.02mg/kg). Repeat
4 hourly until neurotoxicity improves (maximum 10
mg/24hrs)/ Edrophonium
Atropine: 0.6mg IV / Glycopyrolate
FFP and cryoprecipitate or whole blood

41. Treatment of
the Bitten Part
Elevation of limb with rest.
Simple washing with antiseptic solution like
chlorhexidine, povidone iodine etc.
Tetanus toxoid IM injection should be given. If patient
presents with coagulopathy, it should be postponed
until after resolution of coagulopathy.
In case of local necrosis and gangrene: Surgical
debridement.
Broad-spectrum antibiotic if features of infection.

42. Prevention
of
Snakebite
Community based education.
Keep household clean by cutting grasses, bushes, and
plants, remove heaps of rubbish, building materials etc.
Bamboo, wood piles should be removed from
household so that snake cannot hide.
Close door, windows properly.
Try to avoid sleeping on floor. If it is unavoidable, then
mosquito net should be used and tucked well under the
mattress or sleeping mat.
Keep your granary away from the house, it may attract
rodents that snakes will hunt

43. Cont..
Use high shoes or boots while walking in paddy field,
bushes, long grasses.
In dark, use light or strike the path using stick.
Never play with snakes or irritate them even if they are
dead. Never provoke them, they usually do not bite if
not irritated or provoked.
Never insert hands into long grasses, tree holes or mud
holes. Take care while pulling straw.
Shoes and cloths should be check before wearing, in an
area where snakes are abundant

44. Nursing
care
1
Ensure airway,
breathing, and
circulation
2
Keep patient calm
and still
3
Record vitals
every 15–30
minutes
4
Monitor for signs
of envenomation
5
Start IV line and
prepare for
antivenom if
indicated
6
Educate family
members about
do’s and don’ts
Provide emotional
support

45. References
•National Guidelines for Snakebite Management in Nepal- 2019