Pharmaceutical-Nanotechnology introduction to pharmaceutical nanotechnology

introduction to pharmaceutical nanotechnology

1. Pharmaceutical Nanotechnology This course delves into the fundamentals of nanotechnology in biomedical and pharmaceutical research. It will guide students to understand how nanomaterials can be used for a diversity of analytical and medicinal rationales.

2. Unit I: Nanostructures 1 Preparation and Characterization This unit explores the methods for preparing and characterizing various nanostructured materials. It covers techniques like self-assembling nanostructures, vesicular and micellar polymerization, and nanofilms. 2 Metal Nanoparticles The unit delves into the properties and applications of metal nanoparticles, including their use in drug delivery and diagnostics. 3 Lipid Nanoparticles and Nanoemulsions Students will learn about the formation, properties, and applications of lipid nanoparticles and nanoemulsions in drug delivery and cosmetics. 4 Molecular Nanomaterials The unit concludes with an introduction to molecular nanomaterials, such as dendrimers, and their potential in biomedical applications.

3. Unit II: Nanotechnology in the Biomedical Industry 1 Reconstructive Intervention and Surgery This unit explores the use of nanotechnology in reconstructive surgery, including the development of nanomaterials for bone substitutes and dentistry. 2 Implants and Prosthesis Students will learn about the role of nanotechnology in the development of advanced implants and prosthesis, enhancing their biocompatibility and functionality. 3 In Vivo Imaging The unit covers the use of nanomaterials for in vivo imaging, enabling the visualization of biological processes and disease states at the cellular level. 4 Nanorobotics in Surgery Students will explore the potential of nanorobotics in minimally invasive surgery, offering precise and targeted interventions. 5 Nanocarriers for Drug Delivery The unit focuses on the development of nanocarriers for sustained, controlled, and targeted drug delivery systems, enhancing therapeutic efficacy and reducing side effects.

4. Unit III: Nanotechnology in Cancer Therapy Cancer Cell Targeting and Detection This unit explores the use of nanotechnology for targeted delivery of drugs and imaging agents to cancer cells, enhancing therapeutic efficacy and minimizing side effects. Polymeric Nanoparticles for Cancer Treatment Students will learn about the development and application of polymeric nanoparticles for cancer treatment, including their mechanisms of action and advantages. Cancer Imaging and Immunotherapy The unit covers the use of nanomaterials for cancer imaging, including magnetic resonance imaging, and their role in cancer immunotherapy.

5. Unit IV: Nanotechnology in Cosmetics Polymers in Cosmetics This unit explores the use of polymers in cosmetics, including their roles as film formers, thickeners, and hair coloring agents. Conditioning Polymers and Silicons Students will learn about the application of conditioning polymers and silicons in shampoos, conditioners, and other cosmetic products. Emulsions and Stimuli Responsive Polymeric Systems The unit covers the formulation of emulsions and stimuli-responsive polymeric systems for targeted delivery of cosmetic ingredients. Nano Gels, Shampoos, and Hair Conditioners Students will explore the use of nanotechnology in the development of nano gels, shampoos, and hair conditioners, enhancing their performance and efficacy.

6. Unit V: Nanotoxicity Introduction to Nanotoxicology This unit explores the potential risks associated with the use of nanomaterials and the emerging field of nanotoxicology. Dose Relationship and Hazard Classification Students will learn about the dose-response relationship of nanomaterials and how they are classified based on their potential toxicity. Risk Assessment and Management The unit covers the principles of risk assessment and management to ensure the safe use of nanomaterials and minimize potential hazards. Factors Affecting Nanotoxicity Students will explore how the size, shape, and surface chemistry of nanomaterials can influence their toxicity. Organ-Specific Effects The unit examines the potential effects of nanomaterials on the skin, lungs, nervous system, and cardiovascular system. Gene-Cellular and Molecular Interactions Students will learn about how nanomaterials can interact with cells and molecules, including their potential to alter gene expression and cellular function.

7. Course Outcomes CO1 Identify the process for the preparation and characterization of the different nanostructured materials. CO2 Apply nanotechnology in biomedical disciplines related to drug delivery and disease diagnosis. CO3 Develop processes and experiments, applying them in a societal and global context. CO4 Design and develop processes with suitable equipment for the preparation of nanomaterials in developing cosmetic products. CO5 Understand ethical principles to confirm the safety of nano products with respect to risk assessment and its management. CO6 Have knowledge about nanotechnology products and their different applications in a societal and global context.

8. Textbooks and References Springer Handbook of Nanotechnology Edited by B. Bhushan, Springer-Verlag 2004 Nanobiotechnology: Concepts, Applications and Perspectives Edited by C.M. Niemeyer and C.A. Mirkin, Wiley, 2004 Nanotechnology: Health and Environmental Risks By Jo Anne Shatkin, Second Edition, CRC Press, 2013 Cosmetic Nanotechnology: Polymers and Colloids in Cosmetics By Sarah E. Morgan, Kathleen O. Havelka, and Robert Y. Lochhead, American Chemical Society, 2006.