Pharmacognosy of Colophony

Detail Pharmacognosy of Colophony

1. PRESENTATION ON COLOPHONY BIPLOB DEY B.Pharm (2015-19) Dev Bhoomi Institute of Pharmacy & Research Dehradun,Uttarakhand 1

2. Rosin Rosina Colophonium Amber-resin Pine-resin Synonyms- 2

3. Biological Source It is mainly obtained from the species of pinus belonging to the family Pinaceae Plant crude oleo resin Distillation Oil of turpentine Residue (COLOPHONY) 3

4. Geographical Source Its prepared in North America, Northen Europe, Pakistan and India. 4

5. Description Colour - Pale yellow to yellowish brown Odour - Faint & characterstic Shape and size - It occurs in the form of angular, translucent, masses of various sizes . Taste - characterstic 5

6. Insoluble in water BUT S oluble in alcohol, chloroform, ether ,acetic acid and many volatile and fixed oil Solubility 6

7. Standards Melting point- 75 C-85 C Acid value- 130 to 180 Saponification value- 188 to 192 Ash value- Not more than 0.125 % 7

8. Chemical constituent Major constituent of the colophony is Abietic acid (Resin acid) about 90% or vary on the basis of source and storage condition. The colophony also contain 0.5 % volatile oil,pimeric acid and Sapinic acid. 8

9. Identification test Test 1 :- 1 gm of colophony Dissolve in 10 ml of acetic anhydride by gentle heat Add a drop of conc. Sulphuric acid Bright red color changing to violet 9

10. Test 2:- Dissolve colophony in light petroleum ether Make double with dilute solution copper acetate Petroleum layer takes emerald green color (Due to copper salt of abietic acid) 10

11. Uses Pharmaceutical Uses- As a diuretic It is also used in the preparation of some types of Ointments. It is ingredient of certain plaster masses Industrial Uses- Preparation of varnishes Soaps , Printing inks. Soldering compound and as a pressure sensitive adhesive. 11

12. Storage Well closed and well filled container . Away from light and Cool place. In the powder form it gets oxidized quickly and losses its solubility in light petroleum. 12

13. Adulterants:- Colophony is adulterated with black resin or apic resin. 13

14. Thank you for Listening 14

15. QUESTION m 15