Physics Section Mission by International .pptx

Physics Section Mission by International .

1. Nuclear Science & Instrumentation Laboratory (NSIL): Mission and QA related activities Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected]

2. NSIL organizational alignment Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected]

3. Physics Section Mission Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Mission: Supports Member States with regard to the utilization of particle accelerators , research reactors , applications of instrumentation and controlled nuclear fusion Accelerators Nuclear Instrumentation Fusion Research Reactors

4. NSIL Mission Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Mission: Assisting Member States in introducing and extending the use nuclear instrumentation and spectrometry techniques for environmental and other applications Backstopping of Technical cooperation projects Training of TC fellows Organizing information exchange activities (TM, CM, Workshops and Schools) Research aimed to improve analytical performance and to extend applicability (Adaptive Research) Design of nuclear instruments and interfaces Provision of analytical services (MS and other IAEA units)

5. NSIL support to TC Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] National Projects AFG0004 Development of Nuclear Physics Laboratory for Bachelor and Master Students ARG0015 Improving and Strengthening HR in the Areas of Environment, Mining, Nuclear Reactors, Nuclear Fuel, Human Health and Agriculture EGY0019 Supporting Design and Implementation of High Sensitivity Radiation Monitoring Equipment GAB0004 Establishing Preventive Maintenance and Sustainable Management of Medical and Scientific Equipment at the Oncology Institute in Libreville SIL0007 Re-Establishing a Nuclear Science Laboratory at Fourah Bay College for the Training of All Personnel SUD1007 Sustaining Nuclear Instrumentation Maintenance Capabilities (Medical and Scientific Equipment) UZB0005 Improving Training Capacity in Nuclear Science at the National University of Uzbekistan (NUU) and the Samarkand State University (SSU) YEM0004 Improving Nuclear Instrumentation Capability - Phase II

6. NSIL support to TC Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] RAF7016 Establishing and Improving Air Pollution Monitoring RAS0076 Investigating Atmospheric Particulate Matter and Pollution Source Contributions in Urban Environments Using Nuclear Analytical Techniques (ARASIA) RER1015 Apportioning Air Pollution Sources on a Regional Scale RLA0058 Using Nuclear Techniques to Support Conservation and Preservation of Cultural Heritage Objects

7. NSIL support to TC Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected]

8. NSIL RB projects Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Major programme 1 . Nuclear Power, Fuel Cycle and Nuclear Science Programme 1.4 Nuclear Science Project 1.4.3.2 Facilitating experiments with accelerators - IAEAXSpe station at Elettra Synchrotron (Trieste, Italy) - IBA end-station at Institute Ruder Boskovic (Zagreb, Croatia)

9. Facilitating experiments with accelerators Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Ultra-high vacuum chamber designed and built by NSIL in cooperation with PTB Berlin and TU Berlin ( 7-axis stage sample manipulator) 40% of beam time for IAEA use Techniques: GIXRF, XRR, TXRF, XANES Ongoing CRP (8 RAs and 10RCs) IAEAXSpe station at Elettra Synchrotron, Trieste, Italy https://www.elettra.trieste.it/lightsources/elettra/elettra-beamlines/microfluorescence/x-ray-fluorescence.html

10. Facilitating experiments with accelerators IBA chamber at Institute Ruder Boskowic , Zagreb, Croatia Vacuum chamber with multiple detectors 6 weeks/year for IAEA use Techniques: PIXE, RBS, PIGE CRP to be announced

11. NSIL RB projects Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Major programme 1 . Nuclear Power, Fuel Cycle and Nuclear Science Programme 1.4 Nuclear Science Project 1.4.3.3 Nuclear Instrumentation

12. XRF spectrometers available at NSIL Secondary target TXRF Tube + filters

13. m -XRF spectrometers available at NSIL Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Transportable (PART-2) 3 detectors: m -XRF, Confocal and attenuation SEM-EDS

14. NSIL RB projects Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Major programme 1 . Nuclear Power, Fuel Cycle and Nuclear Science Programme 1.4 Nuclear Science Project 1.4.3.4 Developing equipment for environmental monitoring

15. Developing equipment for environmental monitoring Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Detectors available in the Mobile g -spec unit for GPS referenced measurements: Dose rate measurements ( CsI ) Gamma spectrometry with scintillators NaI BGO LaBr CeBr CZT Low altitude airborne measurements

16. In-situ radiological characterization Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Several demonstrations / training made, sites characterized after petitions from Member States Gabon (2012), Kyrgyzstan (2013), Azerbaijan (2013, 2014), Mexico (2014), Argentina (2014), Kenya and Zambia (2015), Uzbekistan (2016)

17. NSIL QA activities Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] Development of recommendations and QMS documentation templates for EDXRF and Instrumentation laboratories Organization of Technical Meetings and training workshops/courses Development of e-learning materials Organization of PT exercises for XRF laboratories

18. October 12-16, 2009 IAEA Technical Meeting on Quality Assurance for Nuclear Spectrometries Recommended responsibilities / duties ( even for a 3 members lab) Head of Institution / Section XRF Lab Head Nuclear Instrumentation Specialist Quality Manager (Lab. Technician) Institution QSM Overall responsibility Head of Institution / Section Technical Manager Implementing and maintaining the Quality System Administrative matters concerning XRF lab operation Control of the work flow Surveillance on the implementation and validation of AI Defining corrective actions In the absence of NIS, realization of analytical services In the absence of XRF Quality Manager, IQC XRF Lab Head Nuclear Instrumentation Specialist Analytical work Maintenance and calibration of instrumentation Implementation and validation of AI Preparation of reports In the absence of XRF Lab Head: Request and report issue Quality Manager (Lab. Technician) Maintenance of QAS Keeping records and documentation Sample preparation and IQC Inventories on CRM, RRM and supplies Preventive actions The QMS is not functional in the absence of more than one member!

19. October 12-16, 2009 IAEA Technical Meeting on Quality Assurance for Nuclear Spectrometries Recommended flow chart for analytical services Y N Y N Y Missing Info? Request XRL accept ? N Contact Customer Request reject Adm. clearance? F.001-A F.001-B F.001-C Acceptance 2 customer Sample receipt Selecting IQC samples Sample prep OR.002 F.003 Remediation plan F.005 Selecting method F.003 OR.002 F.003 Y N IQC? Invest.of causes Preparation of Report Revision Approv Send report OR.002 OR.004 F.005 OR.005 OR.002 OR.015 QAF.002 OF.004 OR.002 Analysis

20. NSIL QM documentation templates Dept. Nuclear Sciences & Applications Division Physical & Chemical Sciences Physics Section Further Information: [email protected] QMS documentation templates for EDXRF laboratories Quality Manual (ISO17025 compliant) addressing recommendations for compliance to managerial and technical requirements SOPs for method validation Assessment of performance (Precision, Trueness, DL) Uncertainty estimation Internal Quality Control Templates for records http://www-pub.iaea.org/MTCD/Publications/PDF/TCS-53_CD/_PUR/index.html

21. QM Document Templates: Quality System Documentation Quality Manual XRL.QM.001 Annexes Specific Procedures XRL.OP.0pp Analytical Instructions XRL.AI.0aa XRL records XRL.OR.0rr Forms XRLF.0ff International Quality Standards & Recommendations Validation reports XRLVR.0vv

22. Specific procedures: XRL.OP.01 - Working flow for analytical services XRL.OP.02 - Sample reception, classification and storage XRL.OP.04 - Realization of internal quality control ( XRL-IQC.xls ) XRL.OP.05 - Reception, conservation and use of RM and CRM XRL.OP.06 – Estimation of uncertainty in XRF analysis

23. Specific procedures: IQC x 1 x 2 DIF s ( x ) 2 Ö2s 3 Ö2s LCL UCL 21 16 5 8 4.19 6.28 0.81 -1.28 18 22 4 8 4.53 6.79 -0.53 -2.79 104 110 6 3 9.08 13.62 -3.08 -7.62 220 245 25 3 19.73 29.59 5.27 -4.59 60 66 6 5 8.91 13.36 -2.91 -7.36 110 119 9 3 9.72 14.57 -0.72 -5.57 … … … … … … … … 104 110 6 3 9.08 13.62 -3.08 -7.62 220 215 5 3 18.46 27.68 -13.46 -22.68 60 66 6 5 8.91 13.36 -2.91 -7.36 110 119 9 3 9.72 14.57 -0.72 -5.57 10 6 4 25 5.66 8.49 -1.66 -4.49 Total 2 % total 9.5 0.0 Internal Control Duplicate analysis (precision) Reference materials (running under control) Analysis of blanks (detection limits and trueness) Thompson M., Wood R, Harmonized Guidelines for Internal Quality Control in Analytical Chemistry Laboratories, Pure  Appl. Chem., Vol. 67, No. 4, pp. 649-666, 1995

24. Special issues in method validation: Applicability Assessment of fitting by sensitivity method Identification of matrix type and determined elemental mass fractions Defining the model Selectivity Identification of potential interferences Calibration and linearity Linear or non-linear model/calibration Identification of matrix effects Trueness and precision Analysis of suitable CRM Working range Quantification model is valid Uncertainty is less than a declared value Detection limit Sensitivity and noise

25. Operational records: XRL.OR.001 - Request for analysis XRL.OR.002 - Work flow of analytical service XRL.OR.003 - Work assignment information form XRL.OR.004 - Report of results of analysis XRL.OR.005 - Results of Internal Quality Control XRL.OR.007 - Inventory of chemical reagents and consumables (XRL-INV_CS.xls) XRL.OR.008 - Service manual and user’s manual instrumentation XRL.OR.009 - Calibration / verification of measurement instrumentation XRL.OR.010 - Results of participation in proficiency tests and inter - comparison exercises XRL.OR.011 - Curriculum Vitae of the staff / Certificates of training

26. Operational records: XRL.OR.012 - Customer’s opinions and suggestions XRL.OR.013 - Results of Management Reviews XRL.OR.014 - Results of Internal Audits XRL.OR.015 - Complaints, non - conformities and corrective actions report XRL.OR.016 - Method validation plan and report XRL.OR.017 - Request for electronic services XRL.OR.018 - Request for PC - service XRL.OR.019 - List of Requests and Goods Received XRL.OR.21 - Control of radioactive reference materials and sources (XRL-INV_RRM.xls) XRL.OR.022. 01 - Working logbook: Sample preparation XRL.OR.022. 02 - Working logbook: SPECTRO X - Lab 2000 spectrometer operation

27. Meetings and Training Courses: Technical Meeting on Quality Assurance for Nuclear Spectrometries , IAEA October 12-16, 2009 Training Workshop on Quality Assurance for Nuclear Spectrometry , IAEA, June 19-23, 2017 RAF7016 RTC on Method validation and Quality Control for the analysis of APM samples , NSIL, May 8-17, 2017

28. e-learning: A Training Module for Quality Management in Calibration, Maintenance and Repair of Nuclear Instrumentation, IAEA-TCS-33/CD Introduction to Quality Management for EDXRF Practice, IAEA-TCS-53/CD http://www-pub.iaea.org/books/IAEABooks/Series/139/Training-Course-Series-CD-ROM

29. IAEA PTXRF: More than 100 laboratories In support IAEA Member States laboratories to identify analytical problems and to improve the quality of their analytical results, Compliant with ISO/IEC17043 (2010): Conformity assessment — General requirements for proficiency testing

30. Conclusions QA-QM activities are well appreciated by the IAEA MSs Support to QA-QM helps the MSs laboratories efforts towards accreditation Forthcoming plans will include QA-QC activities

31. Thanks for your time and attention…