POLY CYSTIC OVARIAN SYNDROME- PATHOPHYSIOLOGY & S/S (OBG) .pptx

PCOS- POLY CYSTIC OVARIAN SYNDROME
NORMAL FEMALE HYPO-THALAMO-PITUITARY-GONADAL AXIS IS EXPLAINED AND WELL ILLUSTRATED IN ABOVE PPT...
TO UNDERSTAND THE PATHOPHYSIOLOGY OF THE PCOS IN THE FEMALES.
HYPOTHALAMO-COMPARTMENT ABNORMALITY.
ANDROGEN EXCESS & HIRSUTISM ,
COMMON SYMPTOMS AND SIGNS ARE EXPLAINED OF PCOS,
OBESITY AND INSULIN RESISTANCE - COMMONLY SEEN IN THE YOUNG ADOLESCENT FEMALES- PCOS.
OTHER LONG TERM CONSEQUENCES AND RISKS ARE GIVEN .

1. PCOS POLYCYSTIC OVARIAN SYNDROME By DR. MD SANEN S BHMS 2019-BATCH AMSHMC BELGAUM

2. NORMAL FEMALE HYPOTHALAMIC-PITUITARY-GONADAL AXIS

3. PATHOPHYSIOLOGY Hypothalamic-pituitary compartment abnormality Androgen excess and hirsutism Anovulation Obesity and insulin resistance Long term consequences

4. Hypothalamic - pituitary compartment abnormality

5. Androgen excess and hirsutism

6. LH surge is essential for ovulation to occur

7. Obesity and insulin resistance Obesity is associated with reduced SHBG apart from excess production of androgens. It induces insulin resistance and hyper insulinemia which increases gonadal androgen production.

8. Long term consequences Increased chances of endometrial cancer. It is caused by endometrial hyper plasia .