Potter syndrome and Potter phenotype refers to a group of findings associated with a lack of amniotic fluid and kidney failure in an unborn infant.

potter syndrome

1. Potter Syndrome Made by- shubham kadiwala,MDE2002

2. What is Potter syndrome? Potter syndrome and Potter phenotype refers to a group of findings associated with a lack of amniotic fluid and kidney failure in an unborn infant. Potter syndrome can affect any baby since the condition is the result of a lack of amniotic fluid. Some studies found that the condition is more common in male infants. Potter syndrome is rare and affects an estimated 1 in 4,000 to 10,000 births.

3. What are the different types of Potter syndrome? Classic Potter syndrome:  Classic Potter syndrome is the most common and is the result of the baby being born without both kidneys. Potter syndrome type I : Symptoms of type I occur because of polycystic kidney disease, where cysts form on the kidneys, caused by the trait passing from both parents (autosomal recessive). Potter syndrome type II : Symptoms of type II are the result of kidney growth abnormalities that occur in the uterus during pregnancy. Potter syndrome type III : Symptoms of type III occur because of polycystic kidney disease similar to type I, but caused by the trait being passed from only one parent (autosomal dominant). Potter syndrome type IV : Symptoms of type IV are the result of a blockage of the urinary tract caused by abnormal fetal development in the uterus (obstructive uropathy).

4. Symptoms and Causes

5. What causes Potter syndrome? Several factors could cause Potter syndrome including: Underdeveloped or missing kidneys. Polycystic kidney disease. Prune belly syndrome (Eagle-Barrett syndrome). Blockages of the urinary tract. Leaking amniotic fluid caused by ruptured membranes. Unmanaged medical conditions in the mother, like Type 1 diabetes.

6. Diagnosis and Tests Minimal urine production. Facial characteristics. Difficulty breathing. several tests to confirm a diagnosis including: A genetic blood test to identify the gene responsible for symptoms. Imaging tests like an X-ray, MRI or ultrasound of your child’s lungs, kidneys and urinary tract. Blood or urine tests to check electrolyte and enzyme levels. An echocardiogram to look for heart symptoms.

7. Management and Treatment Children who survive the disease require management of the following: Pulmonary hypoplasia: Mechanical ventilation and chest tube placement may be indicated for ventilatory support and for the treatment of spontaneous pneumothorax. Renal function: This is assessed with imaging studies and calculation of the glomerular filtration rate (GFR) by using the serum creatinine concentration. Dialysis to remove blood toxins caused by kidney abnormalities.

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