presentation about spirits.pharmaceutical.pdf

This presentation speaks about the spirits in pharmaceutical preparation.

1. Speaking by/ Safwan
spirits
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2. The term “spirit” might conjure images of alcoholic beverages, but in the world of pharmaceuticals, it has
a distinct meaning. This presentation explores the use of specific “spirits,” which are concentrated alcohol
solutions, in various pharmaceutical applications. I’ll delve into their applications, uses, and examples,
highlighting their significance in the pharmaceutical industry.
An important note :
You should know that, there is no big different between elixirs and
spirits only in the addition of alcoholic substance.
Elixirs are made up with non-alcoholic substances while spirits are
Made up with alcoholic substances.

3. Definition
In a pharmaceutical context, “spirits” refer to concentrated
solutions of alcohol, typically ethanol (ethyl alcohol).
Spirits are alcoholic or hydro alcoholic solutions of volatile
substances with solid particles. The active ingredient in the spirit
may be solid, liquid or gases.
These solutions are often denoted by their percentage of alcohol
by volume (v/v), such as:
Alcohol USP (95% v/v ethanol)
Dehydrated alcohol USP (100% v/v ethanol)
“USP” stands for united states pharmacopeia, a quality standard
for pharmaceuticals in the united states.

4. ❖Pharmaceutical spirits have diverse applications in various stages of
drug development and production:
1.Solvent and extraction: alcohol is a versatile solvent for dissolving a
wide range of drug ingredients, facilitating extraction, purification,
and preparation of medications.
2.Sterilization and disinfection: high-proof alcohol solutions effectively
kill bacteria and other microorganisms, making them ideal for
sterilizing surfaces and equipment in pharmaceutical settings.
3.Tincture preparation: tinctures, concentrated liquid extracts of plant or
animal material in alcohol, utilize spirits as a solvent and preservative.
4.Vehicle in topical products: in some topical medications like liniments
and lotions, spirits can act as a solvent and carrier for active
ingredients, promoting penetration and evaporation.
Applications

5. Uses
Antiseptic Solutions: Alcohol
solutions are commonly used as
topical antiseptics for cleaning
wounds and prepping injection
sites.
Flavoring Agent: In some oral
medications, especially for children, a
small amount of alcohol can be used as
a flavoring agent to improve
palatability.
Preservative: Due to its
antimicrobial properties, alcohol
can act as a preservative in certain
pharmaceutical formulations.
Internaly for the
medicinal value
Several used
as inhalation

6. Tincture of Iodine: This topical
antiseptic solution uses alcohol as a
solvent for iodine, a disinfectant.
Vanilla Extract USP: While primarily
used as a flavoring agent, Vanilla Extract
USP meets specific quality standards and
can be used in certain pharmaceutical
applications.
Alcohol Swabs: These pre-moistened
swabs with alcohol are commonly used
for wound cleaning and disinfection.
Examples