PROSTAGLANDINS IN PHARMACOLOGY PRESENTATION

Prostaglandins in Pharmacology

1. Prostaglandins Reported by:Samillano,Mary Rose

2. Prostaglandins   are a group of  physiologically  active  lipid  compounds called  eicosanoids  having diverse  hormone -like effects in animals. Prostaglandins have been found in almost every  tissue  in humans and other animals. They are derived  enzymatically  from the  fatty acid   arachidonic acid .Every prostaglandin contains 20  carbon  atoms, including a  5-carbon ring . They are a subclass of  eicosanoids  and of the  prostanoid  class of fatty acid derivatives.

3. What are prostaglandins? Prostaglandins are a group of lipids with hormone-like actions that your body makes primarily at sites of tissue damage or infection. There are several different types of prostaglandins, and they play several essential roles in regulating bodily processes, including: Blood clot  formation at the site of an injury. Blood flow. Healing. Inflammation . Labor induction  in  pregnancy . Menstruation . Ovulation .

4. How do prostaglandins work? The production of prostaglandins occurs locally, and prostaglandins only act in areas surrounding where they are released and are quickly cleared afterward. Because they are found in almost every organ, prostaglandins act as diverse regulators of the endocrinology and function of the body. Some major functions of prostaglandins include: Controlling pain, redness, and swelling to promote healing during the inflammatory response Regulating immune cells (macrophages and leukocytes) Vasoconstriction or vasodilation (constriction or relaxing of blood vessels) Inhibition of gastrointestinal acid secretion Reducing pressure in the eye Regulating menstruation, including ovulation and menstrual cramps Inducing labor during pregnancy.