Reaction of cyclopropane and cyclobutane

Reaction of cyclopropane and cyclobutane , pharmaceutical organic chemistry sem- 3 B pharmacy second year

1. REACTION OF CYCLOPROPANE & CYCLOBUTANE NAME : KRISHNA UPADHYAY ROLL NO.: 264

2. Cyclopropane & cyclobutane undergoes two types of reactions:     (A). Substitution Reaction     (B). Addition Reaction ( Ring opening Reaction)

3. (A).Substitution reaction SUBSTITUTION WITH Cl2 & Br2  Cycloalkanes reacts with Cl2 & Br2 in the presence of UV light to give substitution products.

4. (B).Addition reaction (1)Addition of Cl2 & Br2 ​ Cyclopropane Reacts with Cl2 & Br2 in Dark to form  addition products. CCl4 is used as a Solvent. ​ Cyclobutane  and higher members don't give this reaction. ​

5. (2) Addition of HBr & HI Cyclopropane reacts with concentrated HBr and HI to yield 1-bromopropane and 1-iodopropane respectively... Cyclobutane and higher members do not give this reaction.

6. (3).Addition of Hydrogen Cyclopropane & cyclobutane reacts with Hydrogen in the presence of Ni catalyst to give propane & n-butane respectively. Higher temperature is required for cyclobutane

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