ResearchTopicGreen synthesis emphasizes the experimental set up of high performing yet cost effective technology that is relatively safe for environment and human.pptx

Green synthesis emphasizes the experimental set up of high performing yet cost effective technology that is relatively safe for environment and human. It aims to minimize the load of chemical waste and ensures sustainable processes to allow economic expansion. It aims to minimize the load of chemical waste and ensures sustainable processes to allow economic expansion.

1. RESEARCH PROPOSAL Presented By, Ayushi Sharma On “Green Synthesis of N anoparticles and their Antimicrobial Properties”

2. INTRODUCTION NPs has four aspects that can be changed which provide us with the versatility to do research keeping in view the international standard & adding more quality work to the community. Nano derived from a Greek word “ nanos ”, meaning dwarf or extremely small. Nanoparticles are particles with a diameter between 1 and 100 nanometers. They exhibit unique properties due to their small size and large surface area . NPs have the ability to change completely and take on characteristics not found in their large counterparts.

3. Objective 1 GOALS AND OBJECTIVES To synthesize NanoParticles (NPs) from plant extract using green chemistry. Objective 2 To characterize the synthesized NPs. Objective 3 To investigate the antimicrobial activity of the NPs against selected sensitive and resistant pathogenic microbes. .

4. Leaves Flowers Stem Roots Fruits Bio reduction Metal Salt Green synthesis of Metallic NPs Antimicrobial test Characterization METHODOLOGY

5. APPLICATIONS 1. Antibacterial Activity : Mechanism: NPs can damage bacterial cell walls and disrupt DNA and protein functions, leading to bacterial death. Examples: Silver NPs are widely used for their potent antibacterial properties, often incorporated into coatings for medical devices to prevent infections. 2. Drug Delivery : Targeted Delivery: NPs can be engineered to target specific types of bacteria or cells, enhancing the effectiveness of antibiotics while minimizing side effects. Bioavailability: Nps can improve the solubility and stability of drugs, ensuring that they reach the desired site of action in the body. 3. Diagnostics: Biosensors: NPs can be used in biosensors to detect pathogens rapidly and with high sensitivity. For instance, gold NPs are employed in lateral flow assays, like those used in pregnancy tests or COVID-19 diagnostics. Imaging: Magnetic NPs can be used in MRI to enhance the contrast, helping in the detection of infections or inflammation at early stages. 4. Vaccine Development: NPs can serve as adjuvants in vaccines, enhancing the immune response to the antigen. Delivery Systems: NPs can protect vaccine antigens and deliver them more effectively to the immune cells. 5. Biofilm Disruption: Biofilms are communities of microorganisms that are resistant to antibiotics and immune responses. NPs Role: They can penetrate biofilms and disrupt the extracellular matrix, making the bacteria more susceptible to treatment. 6. Antiviral Activity : NPs, such as silver or zinc oxide, can inhibit the replication of viruses, offering potential applications in treating viral infections.

6. Conclusion G reen synthesis of nanoparticles using plant extracts represents a promising approach . The eco-friendly method harnesses the natural reducing and stabilizing agents present in plants to produce nanoparticles with unique properties and applications . By avoiding harsh chemicals an reducing energy consumption, green synthesis not only mitigates environmental impact but also offers cost-effective and sustainable alternatives to traditional synthesis methods.

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