spectroscopic study of paracetamol

this content contains UV spectroscopy, IR spectroscopy, H-NMR, C-NMR, and mass spectroscopy of paracetamol.

1. Presented by: Sana Abbas Bs, 2017-kiu-2565

2. TOPIC: Acetaminophen(Paracetamol)

3. Paracetamol: Paracetamol, also known as acetaminophen, is a medication used to treat pain and fever. It is typically used for mild to moderate pain relief. Evidence is mixed for its use to relieve fever. It is often sold in combination with other medications, such as in many cold medications. Formula : C8H9NO2 Molar mass : 151.163 g/mol Other names : N-acetyl-para-aminophenol (APAP), acetaminophen.

4. Spectral analysis: UV-VIS spectral analysis IR spectral analysis H-NMR C-NMR Mass spectroscopy

5. UV-VIS Analysis : UV-Visible spectrum of the product showed wavelength of maximum absorbance at 247 nm. The UV-Visible spectrum of the product obtained was compared with that of pure paracetamol and gave excellent similarities.

6. UV-VIS Analysis :

7. IR Analysis : The IR spectrum showed sharp peaks at 3360 cm- 1 (N–H stretching) A broad peak at 3300 cm-1(O-H stretching) 3090 cm-1 (Aromatic C–H stretching) 1800cm-1 (=C-H bending) 1650 cm-1(C=O stretching) 1600 cm-1 (aromatic C=C stretching) 1570 cm-1 (N-H bending) 1136 cm-1 (C–NH stretching)

8. IR Analysis :

9. H-NMR Analysis :

10. C-NMR Analysis :

11. Mass spectral Analysis :

12. Fragmentation pattern: