StableLab Brochure

1. Equine Blood Analysis. Anytime. Anywhere.
veterinarians

2. Monitoring
Disease
Progression and
Response to
Treatment
In cases where Serum Amyloid A is
detected as a biomarker of disease,
StableLab can be used as a tool to
monitor disease progression and
response to treatment. Detailed
here is an example of where
StableLab was used in this manner.
The SAA levels of a horse that
presented with travel sickness
(pleuropneumonia) were measured
daily for 13 days following a 6689
kilometre transportation (Table
1, Figure 1). Clinical examination,
SAA testing and lung scanning
were carried out by an ambulatory
veterinarian.
The horse was treated with
Ceftiofur (antibiotic), Marbofloxacin
(antibiotic), Flunixin (anti-
inflammatory) Metronidazole
(antibiotic) and Gastrogard
(treatment/prevention of equine
ulcers).
table 1 saa measurements and clinical assessment of a horse with travel sickness.
figure 1 Graphical representation of the data in Table 1
1 379.5 Temp 102, thin, dull. Fluid on right hand side chest and
consolidated lung.
2 3493 Improved condition, temp 101. Lung consolidation.
3 3285 Temp normal
4 3384 Temp normal, consolidation resolving
5 3112 Temp normal, consolidation resolving
6 2640 Temp normal, consolidation resolving, reduced flunixin
7 3960 Temp normal, consolidation resolving,
reduced flunixin
8 2755 Gas pocket in neck, changed ceftiofur to cefquinome
9 838 Scan much improved
10 475 Temp consistent 99.8
11 199 Temp consistent 99.8
12 101 Temp consistent 99.4, stop flunixin
13 39 Scan improved, small comet tails, stop marbocyl
Day saa μg/ml Veterinarian Comments
4500
4000
3500
3000
2500
2000
1500
1000
500
0
1 2 3 4 5 6 7 8 9 10111213
saa (μg/ml)
days
What is
StableLab?
StableLab detects and quantifies
a protein in blood called Serum
Amyloid A. Serum Amyloid A is
normally absent, or only present
in very low concentrations in
healthy horses, but increases
rapidly and dramatically in
response to infection and certain
inflammatory conditions. The
severity of disease is reflected in
the level of SAA elevation, making
StableLab an excellent health
management tool.
This is the StableLab cartridge —>
This line at “C” always appears —
it shows that the test is working.
A second line appears at “T”
if SAA is present in your horse .
You can read the test
result by eye against a
reference card, or use our
handheld reader (see back
page).
Treatment changed here
Monitoring
Disease
Progression and
Response to
Treatment
StableLab can be used as a tool to
monitor disease progression and
response to treatment. Detailed
here is an example of where
StableLab was used in this manner.
The SAA levels of a horse that
presented with travel sickness
(pleuropneumonia) were measured
daily for 13 days following a 6689
kilometre transportation (Table
1, Figure 1). Clinical examination,
SAA testing and lung scanning
were carried out by an ambulatory
veterinarian.
The horse was treated with
Ceftiofur (antibiotic), Marbofloxacin
(antibiotic), Flunixin (anti-
inflammatory) Metronidazole
(antibiotic) and Gastrogard
(treatment/prevention of equine
ulcers).
table 1 saa measurements and clinical assessment of a horse with travel sickness.
figure 1 Graphical representation of the data in Table 1
1 379.5 Temp 102, thin, dull. Fluid on right hand side chest and
consolidated lung.
2 3493 Improved condition, temp 101. Lung consolidation.
3 3285 Temp normal
4 3384 Temp normal, consolidation resolving
5 3112 Temp normal, consolidation resolving
6 2640 Temp normal, consolidation resolving, reduced flunixin
7 3960 Temp normal, consolidation resolving,
reduced flunixin
8 2755 Gas pocket in neck, changed ceftiofur to cefquinome
9 838 Scan much improved
10 475 Temp consistent 99.8
11 199 Temp consistent 99.8
12 101 Temp consistent 99.4, stop flunixin
13 39 Scan improved, small comet tails, stop marbocyl
Day saa μg/ml Veterinarian Comments
4500
4000
3500
3000
2500
2000
1500
1000
500
0
1 2 3 4 5 6 7 8 9 10111213
saa
(μg/ml)
days
What is
StableLab?
StableLab is a new blood test
that’s different in three ways:
it’s handheld, it measures a new
biomarker called SAA, and it
works more like a thermometer
than a lab report, helping you
understand if a horse is sick or
not, right at the horse’s side.
StableLab can be used to detect
infections in horses and it also
tells you if antibiotic treatment
is working.
Treatment changed here

3. How we read it
• We use StableLab when presented with a horse that
has a potential illness.
• A clear result, with no visible test-line indicates
that the horse most likely does not have a systemic
infection.
• If the result is reported as positive and:
– Less than 50 μg/ml, we may continue to monitor
the patient before initiating therapy OR we
may discontinue therapy if the SAA was initially
elevated and the patient finished its course of
treatments.
– Between 50 μg/ml and 200ug/ml we begin
appropriate diagnostics and /or treatments
depending on our physical exam findings.
– Greater than 200 μg/ml indicates the animal most
likely has some sort of systemic illness that will
require more diagnostics and /or treatments.
• On certain cases we will use StableLab to monitor
response to treatments.
recommended protocols
Dr. Nathan Slovis
dvm, dacvim, cht
Moni find that it is an earlier and more sensitive
indicator of equine inflammatory and infectious
diseases than other lab methods. StableLab is
a breakthrough in stall side equine diagnostics,
and presents a new way of blood testing.”
When we use it
We use StableLab as an adjunct diagnostic to
help identify horses that may have a systemic
infection. We also use StableLab to monitor
our patients and how they are responding to
our therapies.
Serum Amyloid A (SAA) is a rapid response
protein with a half-life of approximately 24
hours, it’s the earliest indicator of systemic
inflammation and/or infection.
StableLab helps those who care for the
horse’s well-being by offering testing in an
easy and convenient manner. An increasing
value on StableLab informs our veterinarians
that a disease process may be occurring
and we can respond appropriately (i.e. more
diagnostics or initiate treatment based on
our physical exam) when we see the values
reduce, we gain confidence that our patient is
responding to treatment.
StableLab’s Handheld Reader
The StableLab handheld reader accurately
measures SAA from 0–3000 μg/ml. Take
the StableLab reader with you to record and
track your results anytime, anywhere.

4. patent pending. stablelab®. ©stablelab
2013
. all rights reserved.
Business Innovation Centre, Institute of Technology Campus, Ballinode, Sligo, Ireland
www.stablelab.com · [email protected]
proud to be distributed by:
“SAA is an acute phase
protein. It can help
distinguish between
infectious and non-
infectious diseases.”
Dr Nathan Slovis (Chairman)
“We may not know all
of the answers about
(SAA) but it seems like
it’s changing how almost
everybody is making a
decision.”
Prof Fairfield Bain
“I use it [StableLab]
mainly for respiratory
disease and shipping
fevers.”
Dr Jordan Lewis
“If I have a negative on
(StableLab), I can assume I’m
not going to start antibiotics.
That’s the really fabulous thing —
I’ve got an SAA horse-side
right here, I don’t have to wait
until tomorrow to get the lab
result back.”
Dr Richard Markell
“Now that we have
StableLab we may use
SAA more, because
it’s so easy to use.”
Dr Philippe Benoit
“I use StableLab as a post-
operative monitoring tool,
particularly on horse’s on which
we fix long bone fractures —
for me, with surgical trauma
and [non-infectious] surgical
inflammation, I have not seen any
rise in serum amyloid A.”
Dr Keith Latson
“I’ve looked at it in cases that
I’ve definitely known have had
an infection, pneumonia —
you’ll see a clear rise. I’ve seen
a [non-infectious] inflammatory
bowel disease, I’ve had several
of those this year, and I’ve not
seen a rise.”
Dr Bonnie Barr
“I was convinced early on that
we’re only detecting infection
— I do believe that (a certain
percentage of) horses with 200–
400 SAA can recover on their
own. Then it becomes more of a
management issue with them.”
Dr Luis Castro
“Fibrinogen is a test that
I really don’t run anymore.
I run a CBC and an SAA.”
“StableLab dictates my
worry factor.”
Dr Chris Ray
“One of the important things
for us to know is that a horse
getting off transport has a fever
– whether it’s a mild shipping
stress or something more
important. The sooner we can
know that, the sooner we can
start the appropriate therapy.”
Dr Tim Ober
“We should encourage
that antibiotic use be as
restricted as we can, and
SAA is a great tool in that
I think.”
Dr Jan Hein
Swagemakers
The innovators circle
was very special for
StableLab. We gathered
11 renowned equine
veterinarians from all
over the world because
you our customer wanted
real expert opinion.
The discussion is
unscripted and the
experiences are real
cases expressed by those
who have integrated
Serum Amyloid A into
their practice. I hope you
enjoy it.
Heinrich*
*Dr. Heinrich Anhold
Heinrich is the founder and
CEO of StableLab. He is a
former Junior international
showjumper and holds a PhD
in Biochemistry.
His mission with StableLab
is to deliver simple, practical
health information at the
horse’s side for immediate
and informed decisions.
Putting the power of
knowledge in your hands.
Go to the
StableLab
YouTube channel
to learn more.