-Any hx of trauma (r/o traumatic ulcers)
-Any hx of polyuria, polyphagia, polydypsia and weight loss (r/o DM)
-If patient is a known diabetic, what drugs is he on and how compliant is he to therapy
-Any hx of calf muscle pains –intermittent claudication- to r/o arterial ulcers
-Is patient a known smoker, hypertensive, or diabetic(r/o atherosclerosis)
-Any hx of prolonged immobility ( r/o pressure ulcers)
-Any hx of weight loss, swelling in any part of the body, bone pains (r/o malignancy)
-Any hx of loss of sensation around the leg (r/o neuropathic ulcers)
-Is patient a known sickler (r/o sickle ulcers)
-Any hx of STD in the past with ulcers in other parts of the body (r/o syphilitic ulcers)
Differentials of ulcers
Guineaworm,varicoseveins,trauma,DM,TB,atherosclerosis,pressureulcers,malignancy,
leprosy, sickle cell anaemia, STDs (syphilis), Multiple myeloma
EXAMINATION
General
Musculoskeletal System: Ulcer examination
Other systems (digestive, CVS, respiratory)
Investigations
Woundswab,Mantouxtest,FBC,ESR,urinalysis,VDRL,FBS,CXR,genotype,lipidprofile,SEUCr,
HIV screening
NEPHROTIC SYNDROME
PC: anuria, oliguria, edema, body swelling, uremic symptoms
-Explore the body swelling as above
-How long ago was it noticed ( >3months CRF, <3months ARF)
-Any signs and symptoms of anaemia
-Is patient a known hypertensive or diabetic (nephropathy)