Swiss pdb viewer

Swiss PDB viewer by sivasangari Shanmugam. The protein data bank is a repository for the 3-D structural data of large biological molecules

1. SWISS PDB VIEWER SIVASANGARI SHANMUGAM

2. HISTORY It has been developed since 1994 by Nicolas Guex . It was invented in 1774. It is tightly linked to SWISS –MODEL, an automated homology modeling server developed within the SIB at the structural bioinformatics group at the Biozentrum in Basel.

3. SWISS PDB VIEWER The protein data bank is a repository for the 3-D structural data of large biological molecules. Eg ; Protein The data typically obtained by X-Ray crystallography (or) NMR spectroscopy. It is a key resource in area of structural biology.

4. A tool for viewing and manipulating protein structures and models. Provides a user friendly interface allowing to analyze several protein at the same time. Make molecular surfaces. Align multiple protein. Apply scoring functions. Simple, fast modelling including site-directed mutagenesis. Complex modelling including loop rebuilding. Amino acid mutations, H-bonds, angles and distances between atoms are easy to obtain.

5. SWISS PDB VIEWER Downloading the PDB file; http://www.rcsb.org/pdb/home/home.do Downloading Swiss-PDB Viewer; http://spdbv.vital-it.ch/download.html

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20. USES To find Hydrogen bonds within proteins & between proteins & ligands. To view several protein structures simultaneously & superimpose them to align their structures & sequences. To examine electron –density maps from crystallographic structure determination. To judge the quality of maps & models. To identify many common problems in protein models. It computes electrostatic potentials & molecular surfaces,& carries out energy minimization.

21. THANK YOU