Synthesis of Fluoroalkenes by Gold Catalysis.pptx

Organic chemistry methodology

1. 1

2. Ester-Directed Hydrofluorination of Alkynes 2

3. 3 Nitrogen-Containing Directing Groups for Hydrofluorination of Alkynes Hydrofluorination of Dicarbonyl Substrates Possible Intermediates that Interrupts the Hydrofluorination of 29

4. 4 Mechanistic Hypothesis for the Directed Hydrofluorination of Alkynes

5. 5 Thanks for your time!!

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7. Gold-Catalyzed Allylation Reaction 7 Scope of α- and γ-Substituted Allyl Acetates/Alcohols Scope of Indoles Scope of α-Phenyl Allyl Acetates

8. Control Experiments and Proposed Mechanism 8 Stoichiometric Experiments Highly asymmetric π- allyl complex having ( σ+ π ) - coordination with allyl fragment asymmetric π- allyl complex

9. 9 Deuterium Labeling Experiments Catalytic Experiments Stoichiometric Experiments