Thal care and prevention and way forward.pptx

thal treatment cure and prevention

1. Care, control, Cure in Thalassemia

2. Our Mission So far what we have learnt Three C’s for Thalassemia Pts Care Cure Control

3. Care: Thalassemia Minor No specific treatment Always Hb 10-13 gm% Do not take any medicines to increase Hb

4. How many of these are anemic?? If Hb less than 10 gm%, Iron deficiency Care: Thalassemia Minor

5. Why do we want to identify Thal Minor?? Their main role: To be partner in the prevention of birth of any Thalassemia Major Care: Thalassemia Minor

6. Care: Thalassemia Major Regular blood transfusion Initially 3-weekly and then frequency increases Life-long blood transfusion is not the ideal solution; but the only option for most

7. Blood transfusion: safe and regular Maintain pretransfusion Hb> 9.5gm% Availability (2 M units per year), Donors Packed cell Filters Safety: NAT tested; Risk of blood borne infections

8. Its just beginning of the problems.. Iron oveload Chelation Cost Side effects Availability Compliance

9. Its just beginning of the problems.. Regular monitoring Growth and development Liver Heart Hormonal issues Diabetes

10. Cost of treatment Average1 lakh per year Increases as age progresses Co-morbidities

11. Real Cost Child: Misses school Pricks Growth and development Parents: Office Care of other children Society: Donors Govt : Burden on resources

12. So Thalassemia Major means Problem hi Problem

13. Control or prevention: Why?? Prevention 10,000 Thalassemia Major new born every year 1,00,000 under care Notice the difference in numbers Long term goal: No child should be born with Thalassemia Major

14. How to prevent Know your Thalassemia status CBC Hb , MCV, RBC Count Hb 9-12 gm% MCV low: <80 RBC count high:>5 M

15. HPLC HbA2> 3.5% Encourage: Sibling screening

16. What to do with report?? Donot Panic You do not have something: which affects longevity or quality of life Pre marital: Check Thalassemia status of partner If Normal: Nothing to be done

17. Amniocentesis During pregnancy: 6-10 weeks genetic testing Amniocentesis/ chorionic villus sampling If Minor/Unaffected: Nothing to be done

18. Prevention Chances of Thal Major: 25% If Major: Termination of pregnancy

19. Can Thalassemia be prevented Small countries like Cyprus, Italy, Greece; No Thalassemia It has been achieved primarily by Pre marital screening

20. Awareness campaign about prevention and Team work

21. Thank you