TOPIC-OXIDATIVE and PHOSPHORYLATION.pptx

About oxidative phosphorylation

1. TOPIC-OXIDATIVE PHOSPHORYLATION PRESENTED BY-SHEKHAR JYOTI DAS ROLL NO-230404001 BRANCH- BIOTECHNOLOGY 3 RD SEM

2. Oxidative phosphorylation is the final step in cellular respiration. It occurs in the mitochondria. It is linked to a process known as electron transport chain. The electron transport system is located in the inner mitochondrial membrane. The electrons are transferred from one member of the transport chain to another through a series of redox reactions What is Oxidative Phosp horylation

3. Fig-Oxidative Phosphorylation

4. Oxidative phosphyorylation is combination of electron transport chain and chemiosmosis . In electron transport chain the electron get shuffeled from one complex to another complex( complex I to IV) In chemiosmosis the ATP synthase pumps the proton gradient to generate ATP. Oxidative Phosphorylation Steps The major steps of oxidative phosphorylation in mitochondria include :

5. Delivery of Electrons by NADH and FADH2 Reduced NADH and FADH2 transfer their electrons to molecules near the beginning of the transport chain. After transferring the electrons, they get oxidised to NAD+ and FAD and are utilised in other steps of cellular respiration.

6. Electron Transport and Proton Pumping The electrons move from a higher energy level to a lower energy level, thereby releasing energy. Some of the energy is used to move the electrons from the matrix to the intermembrane space. Thus, an electrochemical gradient is established. Splitting of Oxygen to form Water The electrons are then transferred to the oxygen molecule which splits into half and uptakes H+ to form water.

7. ATP Synthesis The H+ ions pass through an enzyme called ATP synthase while flowing back into the matrix. This controls the flow of protons to synthesize ATP.