Toxic shock syndrome by Suramya babu

Toxic shock syndrome is often caused by the Staphylococcus aureus (Staph) and less commonly Streptococcus pyogenes bacteria which are able to produce harmful toxins.

1. TOXIC SHOCK SYNDROME SURAMYA BABU BSC MLT

2. TOXIC SHOCK SYNDROME is a rare , life threatening condition caused by bacteria getting into body and releasing harmful toxins

3. Toxic shock syndrome is often caused by the Staphylococcus aureus (Staph) and less commonly Streptococcus pyogenes bacteria which are able to produce harmful toxins. The bacteria release toxins into your bloodstream which cause symptoms of shock. The toxins can also damage organs and body tissue, which can cause death if left untreated.

4. Toxic shock syndrome has been associated with Having cuts or burns on your skin Having had recent surgery Using contraceptive sponges , diaphragms, superabsorbent tampons or menstrual cups Having a viral infection such as flu or chicken pox

5. Symptoms of TSS Headache High fever Peeling of skin of palms and soles of feet Rash on hands and feet Reddened eyes diarrhoea Tachycardia Seizures Fainting Low blood pressure

6. complications H ypotension Shock Renal failure Liver failure Heart dysfunction Adult respiratory distress syndrome Death

7. Routes of infection Vagina Cuts and wound Nose Surgical and skin wounds

8. Pathophysiology

9. DIAGNOSIS There is no one test for TSS. Difficult to diagnose until characteristic symptoms evolves and source of infection is identified Blood culture Throat and vaginal swabs Blood test

10. Lab diagnosis of toxic shock syndrome (TSS) Present in >70 % of patients Platelet count <15000 / mm3 pyuria > 5 WBCs per HPF Proteinuria Bun > 20 mg/Dl SGOT > 41 U/L

11. Treatment A ntibiotics to treat the infection Pooled immunoglobulin (purified antibodies taken out of donated blood from many people) oxygen to help with breathing Fluids to help prevent dehydration and organ damage Medication to help control blood pressure Dialysis if the kidneys stop functioning In severe cases, surgery to remove any dead tissue – rarely, it may be necessary to amputate the affected area