UprightVR

UprightVR's SafetyNet Solution: A low-cost, ultra-portable, scientifically validated Virtual Reality solution for assessing fall risk, identifying deficits and shaping treatments.

1. This presentation is the confidential unpublished property of UprightVR . All rights reserved. 1 Geoff Wright, Ph.D. Chief Science Officer UprightVR Inc. [email protected]

2. UprightVR’s SafetyNet TM Solution A low-cost, ultra-portable, scientifically validated Virtual Reality solution for a ssessing f all risk, i dentifying deficits and s haping t reatments. Catch them before they fall… 2 VR Headset 2 Foam pads Tablet or laptop Carrying case Gait belt Total weight: 5 lbs. The Product The Process Test anywhere Need standing room only Takes less than 10 minutes Eight 20 sec assessments Immediate results (see patient report)

3. Technology Overview 3 Catch them before they fall… In a series of brief tests taking less than 10 minutes, deficits are isolated and quantified in the central integration and functional use of sensory systems including somatosensory, visual, and vestibular. 8 sensory conditions are presented through virtual reality Postural response is measured and recorded in a self-contained VR headset, without the need for any other equipment. D eficits in the central integration and functional use of sensory systems are identified. Risk factors based on these deficits are correlated to actual functional risk (see patient report), leading to targeted therapeutic intervention. Periodic reassessment tracks the impact of the therapeutic response, and changes in risk levels. The VR technology is inexpensive, ultra-portable, easy to administer and fun for the patient or senior resident.

4. Extensive lab validation complete Meets or exceeds all CDP sensitivity and specificity metrics 3 IRB studies complete – dominates observational methods Four field trials completed; large pilots in progress Validation 4 Catch them before they fall…

5. UprightVR’s SafetyNet Patient Report 5 Patient-friendly clinical interpretation Natural degeneration Intervention impact Medical event trigger Science-based clinical interpretation Fall Risk Tracking Uncovers: Neuro pathologies Sensory & motor deficits Musculoskeletal deficits Catch them before they fall…

6. Systematic Fall Reduction Process 6 Neurological pathologies Sensory & motor deficits Central Integration Musculoskeletal deficits Correlation to functional risk 1. Fall Risk Assessment Measure Intervention Impact Track Natural Degeneration Identify New Deficits At-risk residents Fall risk profile trends Intervention effectiveness Resident retention Fall reduction 4. Patient Monitoring Referral – PC, Neurologist, PT, Audiologist Targeted physical therapy interventions Targeted wellness program Medication adjustment Lifestyle changes 3. Targeted Intervention Catch them before they fall… Neuropathologies Sensory Motor Deficits Musculoskeletal Degeneration 2. Identify Deficits

7. A Better Solution Functional Tests (e.g. TUG, BERG Balance Test) Assesses risk only. No casual indicators. Subjective, widely practiced observational approach Does not always indicate subtle changes over time Does not identify deficits 7 Computerized Dynamic Posturography (CDP) Neurocom Balance Master, previously established the gold standard Not easy for patients to access Impractical widespread solution Not portable: 53 in x 61 in x 94 in UprightVR Equals or exceeds Neurocom in fall prediction accuracy Cost = $3.5K, plus subscription for tracking trends Portable, reliable VR technology Increases clinician revenue and productivity Easy to administer by trained operators Easy access to patients where they live Supports prevention of first-falls Catch them before they fall…

8. 8 LHC Group 7 locations in 3 states Powerback Rehabilitation (formerly Genesis) 2 locations in PA The Villages 3 clinics 102 residents assessed 64% high fall risk Rated experience 4.72 out of 5.00 St. James Place Baton Rouge Full implementation Noteworthy Field Validation & Pilot Programs Catch them before they fall…

9. Successful First Implementation 9 St. James Place Wellness Fair (March 2022) 72 residents of 180 signed up for testing The Results: 17 referred to PT with contracted PT company 2 referred for vestibular rehab 9 referred for in-home balance training 3 medium risk residents referred to balance & education services 8 at-risk patients already in physical therapy 10 high risk residents were unaware of any fall risk Seniors embraced the technology Significant revenue generation Catch them before they fall…

10. Impact of Therapeutic Response 10 Catch them before they fall…

11. Q uinn , Ellis, Reter , Wright. “Detecting Risk of Falls in Healthy Older Adults Using a Virtual Reality Balance Assessment."   APTA CSM, San Antonio, TX, 5 Feb 2022. https://apta.confex.com/apta/csm2022/meetingapp.cgi/Paper/33557 Wright WG, Handy J, Haskell, Servatius L, Servatius R (2022). History of Mild Traumatic Brain Injury Affects Static Balance Under Complex Multisensory Manipulations. J Neurotrauma . 39:821–828. Ma L, Wright WG . “Validation Study of a Wireless Virtual Reality Head-Mounted Display for Sensory Integration in Balance Testing of Older Adults.” International Conference on Virtual Reality. July 2021, Virtual.   Marchetto J, Wright WG (2019). The validity of the Oculus Rift to assess postural changes during a balance tasks. Hum Factors , 61(8):1340-52.   Wright WG, Handy JD, Avcu P, Ortiz A, Haran FJ, Doria M, Servatius RJ (2018). Healthy Active Duty Military with Lifetime Experience of Mild Traumatic Brain Injury Exhibits Subtle Deficits in Sensory Reactivity and Sensory Integration During Static Balance. Mil Med .183(suppl_1):313-320. Wright WG , McDevitt J, Tierney R, Haran FJ, Appiah-Kubi K, Dumont A (2017). Assessing subacute mild traumatic brain injury with a portable virtual reality balance device. Disability and Rehabilitation , 39(15):1564-72. Wright WG , McDevitt J, Appiah-Kubi K (2015) A portable virtual reality balance device to assess mild traumatic brain injury symptoms: A pilot validation study. IEEE Proc ICVR2015 , pp 72-79. doi : 10.1109/ICVR.2015.7358591 Validation 11 Catch them before they fall…

12. This presentation is the confidential unpublished property of UprightVR . All rights reserved. 12 Geoff Wright, Ph.D. Chief Science Officer UprightVR Inc. [email protected]