Comparative market potential study between four drugs for treatment of Osteoporosis in two Asian metropolitan cities of Bangalore and Tehran Saeed Akbarian M- pharm 2 nd year 09PM105
OSTEOPOROSIS silent dangerous disease which can be fatal
DECREASED BONE DENSITY Low bone mineral density leads to frequent fractures of bones
Objectives To determine the position of anti-osteoporosis medications in the market. To arrive at the most widely prescribed anti-osteoporosis medicine. To determine the share of each anti-osteoporosis medicine for prevention &/ treatment of the osteoporosis condition To determine the factors influencing rate of physician's prescriptions for each medicine
According to IMS Health Osteoporosis market share for different groups of products are as follow: (Prescription Sales Only) Bisphosphonates 35.3%; Estrogens 32.8%; Bone Den. Reg. (SERMs) 10.1%; Calcitonins 5.3%
Medications chosen for this study include: Alendronate Sodium Risedronate Sodium Ibandronic acid Tablet Strontium Ranelate
Alendronate Sodium 10mg and 70mg tablets The original brand is Fosamax Bisphosphonates anti- resorptive medication Approved for the prevention and treatment of postmenopausal osteoporosis & osteoporosis that is caused by cortisone-related medications
Actonel 35mg tablet
Ibandronate Ibandronate an oral bisphosphonate for prevention and treatment of postmenopausal osteoporosis Monthly oral formulas as well as intravenously every three months The product bioavailability is 0.6% only and bounded to proteins by 90-95%
Strontium ranelate both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts It is therefore promoted as a "dual action bone agent" (DABA)
Sources of data: a) Primary data: Through questionnaire method primary data will be obtained from doctors & pharmacist b) Secondary source : The related information will be obtained from: Text books on disease management Scientific journals Pharma biz Internet
1- Number of Prescriptions received by pharmacies per day Tehran Bangalore
2- Rank of category of specialists prescribing anti-osteoporosis products Tehran Bangalore
3- Awarness to the pharmacists Tehran Bangalore
4- Average no. of prescriptions receiving for each product Tehran Bangalore
5-promotional activity rate for each product Tehran Bangalore
6- Availability of products Tehran Bangalore
Number of patients being visited by Doctors Tehran Bangalore
Rate of awareness of the products to the doctors Tehran Bangalore
How did you first get familiar by any of above products for treatment or prevention of Osteoporosis? Tehran Bangalore
Which of the following products do you prescribe for treatment or prevention of Osteoporosis? Tehran Bangalore
Percentage of specialists prescribing formulas for treatment of fractures Tehran Bangalore
which of the following products are more effective for prevention or treatment of osteoporosis? Tehran Bangalore
rank of the products as per their convenience to be taken Tehran Bangalore
which of the following product are easily available to your patients? Please rank them. Tehran Bangalore
which of the following product are being presented to you by companies? Please rank them Tehran Bangalore
As an specialist, how much do you think advertisement by companies is important for the product to be prescribed by you? Tehran Bangalore
What are the factors that influence your opinion while prescribing anti-osteoporosis medications Tehran Bangalore
Which one of these medicines do you usually prescribe with anti-osteoporosis medicines? Tehran Bangalore
conclusion Awareness Effectiveness Patient Compliance Availability Price Administration Alendronate has a better market, and Ibandronic Acid can have better market
As the conclusion show Alendronate is the drug of choice for chemists and doctors and also it is the most available and cheep drug in both countries Both patients and doctors prefer effective, available and cheep drugs in Bangalore and in case of Tehran effectiveness and availability is more important Residronate is more used in Bangalore than in Tehran which can be due to availability Strontium Renalate is an effective drug, but being less used compared to bisphosphonates which can be the result of it’s price and availability
Calcium supplements are used almost the same in both cities and these shows the doctors are aware enough about the mechanism of action of these drugs . It is a good idea if a company work on a product containing an anti-Osteoporosis product along with Calcium supplement For a company intending to enter to Osteoporosis segment in Tehran Strontium Renalate is a good choice and in case of Bangalore Residronate and Ibandronate are good choices