Wolff kishner reduction with mechanism

It includes reaction and it's mechanisms and it's applications. It also contains limitations about the reduction.

1. TOPIC W OLFF - K ISHNER R EDUCTION PRESENTED BY K.MUTHU KANNAN

2. WOLFF-KISHNER REDUCTION : The Wolff Kishner reduction was discovered by Nicolai Kishner in 1911 and Ludwig Wolff in 1912.It involves the reduction of carbonyl compounds to hydrocarbon by heating with hydrazine and a base. In this process the carbonyl group is converted to methylene group and nitrogen gas evolves out, which is a side product of reaction and ethylene glycol is used as a solvent.

3. Mechanism:

4. Exambles :

5. Applications: This reaction has widely used to convert a carbonyl group into methylene group. Also important application in the preparation of polycyclic aromatics and aromatics containing unbranched side hydrocarbon chains. To reduce aliphatic and mixed aliphatic-aromatic carbonyl compounds.

6. limitations: The reduction requires a high temperature. Although the process is specific for carbonyl groups, sometimes migration of the double bond takes place instead of the expected mechanism of the reaction when undesired product like alpha, beta-unsaturated carbonyl compounds are formed in the reaction.

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