Antimicrobial Consumption Surveillance through WPRACSS: Introduction for Indonesia MOH August 8 th , 2025
Why conduct antimicrobial consumption (AMC) surveillance? WPRACSS background WPRACSS web portal Comparing and linking with GLASS-AMU Overview
Four beads in a chain: Interconnected AMR activity areas Strengthening these interconnected AMR activity areas provides a systems approach to addressing AMR in the Region Antimicrobial Consumption Surveillance AMR Surveillance Antimicrobial Stewardship AMR outbreak response
AMC data Makes comparisons across local, national, and international levels. Provides essential information on service delivery Assesses the outcomes of actions or policies to understand the volume and patterns of antimicrobial consumption Detects trends over time and evaluate prescribing practices and the appropriateness of antimicrobial use
WHO Tools WPRACSS https://www.who.int/westernpacific/health-topics/antimicrobial-resistance/wpracss WHO GLASS-AMU https://www.who.int/initiatives/glass/glass-amc-module
https://iris.who.int/bitstream/handle/10665/351130/9789290619543-eng.pdf?sequence=1&isAllowed=y Build capacity for AMC/AMU surveillance and monitoring systems in countries/areas Utilize data and analytical insight to help strengthen stewardship ; plan policies and improve health outcomes Establish a regional database on AMC/AMU Provide regional analyses and suggestions to MSs Issue reports . WPRACSS approach
WPRACSS Overview WPRACSS supports Member States through: Capacity-building Technical briefings and trainings on collection, analysis, and use of AMC data Manuals drafted for AMC monitoring at national, hospital, and community levels Web portal performs data validation and analysis
8 WPRACSS Participation No. of WPRO countries enrolled to WPARCSS : 22 Data received from 2018-2021: 10 Data received in 2023 (2022 data): 8 Data received in 2024 (2023 data): 7 Countries with 2018-2023 data WPR Countries In total, 22 countries and areas are participating in WPRACSS . In 2024, six Pacific island countries enrolled in WPRACSS.
08/08/2025 | Title of the presentation 9 Publication of the first regional report - early implementation of WPRACSS - This report presents results from national-level monitoring of antimicrobial consumption data in 2018 to help assess antibiotic use across the Western Pacific Region. 9
Source: WHO Report on Surveillance of Antibiotic Consumption (2016-2018 Early Implementation) Pharmaceutical value chain AMC AMU
WPRACSS preferred data sources for national level AMC surveillance
WPRACSS template Product ID Product name Active ingredients in INN Route of Administration Strength Strength unit Concentration volume only valid for oral solutions (i.e. syrup) Concentration volume unit Package size The number of items of the medicinal product in the package. Packsize unit Unit of measurement of number of items per package (PCS, G, ML) Total Packages The total number of packages of the antimicrobial consumed during the given period ATC5 The WHO ATC code at substance level (ATC 5 level code) is used to calculate DDD by active substance Salt_code The salt code associated with the active substance Dosage Form Pharmaceutical formulation type Product Origin or Manufacturer's Country Manufacturer Data source 21800AMX10 Amoxycillin amoxicillin O 500 MG 1000 PCS 250 J01CA01 Tablet USA Import e .g product registration number The product name printed on its label The pharmaceutical substance written on the product label how the product is administered amount of active ingredient present in each dosage form The unit of the strength of the medicinal product
Online portal Login - Western Pacific Region Antimicrobial Consumption Surveillance System (who.int)
Western Pacific Regional Antimicrobial Consumption Surveillance System Support for Member States in AMC situation analysis : The system is designed to empower Member States to conduct their own assessments rather than functioning as a regional surveillance tool. Efficient Data Collection and Visualization : The process for collecting and visualizing data is simple and less time-consuming, facilitating easier participation and more effective monitoring. Integrated Analysis : By linking Antimicrobial Consumption (AMC) data to qualitative information, the system contextualizes quantitative surveillance results, providing a more comprehensive understanding of antimicrobial use and resistance patterns WPRACSS One-stop Portal
WPRACSS Dashboard Total volume of antimicrobials in DDD Total DDD/1000 inhabitants/day for the whole country/area AWaRe ( Access, Watch and Reserve ) classification Route of administration (parenteral versus oral) Top 10 consumed antimicrobials by the route of administration
GLASS-AMU overview 90 countries enrolled in GLASS AMU (end of 2023) 74 countries submitted data to GLASS-AMU from 2021-2023 6 WPR countries enrolled in GLASS-AMU: Brunei Darussalam, Lao PDR, PNG, Republic of Korea, Mongolia, and Indonesia With country permission, WPRACSS coordinates data sharing with GLASS-AMU GLASS-AMU and WPRACSS methodologies are aligned (antimicrobials for systemic use, ATC/DDD, annual submission, variables, indicators) Routine GLASS surveillance module - Annual submission of national AMC data by countries Closed system - formal country enrolment/NFP assignment for GLASS-AMU module (different from GLASS AMR enrolment)
Comparison of WPRACSS / GLASS-AMU 17 WPRACSS GLASS-AMU Antimicrobials for surveillance Core: J01, A07AA, P01AB Optional: J02, D01BA, J05, J04A, P01B Core: J01, A07AA, P01AB Optional: J02, D01BA, J05, J04A, P01B Classification and measurement methodology ATC/DDD ATC/DDD Coverage Western Pacific Region Global Data collection Excel template Product, substance, and basket-level options Excel template Product and substance-level options Data validation Conducted on web-portal Conducted by Excel macros function Key indicators Total DDD, DID, Route of Administration, ATC3 level, top 10 substances by route Total DID by antimicrobial class, Route of Administration, ATC3 and ATC4 level Web portal functionality Analysis of national, hospital, and community level AMC data Online database and dashboard for reporting national AMC data
Considerations for IDN enrolling in WPRACSS No additional workload/burden on IDN as already preparing and submitting national data for GLASS-AMU WPRACSS coordinates data sharing with GLASS-AMU upon approval by member states WPRACSS additionally supports hospital and community-level monitoring to further deepen understanding of AMC patterns in IDN Contribute to regional reports of AMC and compare data with countries of similar context 18