By, Mr.Chechare D.D. Lecturer , PRES’s College of Pharmacy (D.pharm)Chincholi. NUTRITION & HEALTH
Nutrition It is a science of food & its relationship to health. Nutrition are specific dietary constitution such as Carbohydrates, Proteins, Fats, Vitamins & Minerals.
Food I t is defined as any substances which when taken into body can be utilized to provide heat or energy to maintain or to compensate wear and Tear of tissue and regulate the body process. Functions of food To provide heat and energy for mechanical work To maintain the wear and Tear of tissue Essential for growth of the body Provide the power to the body to build resistance against infectious disease It Is Essential to satisfy hunger It is essential for maintenance and regulation of body temperature
classification of food 1 . A ccording to origin Animal source example meat, fish, eggs, milk Vegetable source example green vegetable, fruits, oils, dry fruits M inerals source example all minerals are like sodium, chloride potassium 2 . According to function Energy building foods like carbohydrates, fats, protein B odybuilding fruits like meat, fish, eggs ,milk protective foods like milk and green vegetables 3 . A ccording to nutritive values E xample animal food, fats, oils, nuts, cereals and spices 4. According to chemical composition example Carbohydrate, protein, fat, minerals, vitamins
CARBOHYDRATE Carbohydrate consists of carbon, hydrogen and oxygen. It is the main source of energy and one gram of carbohydrate after oxidation yield 4 Calories of energy. All carbohydrate have to be changed into glucose and Fructose before they are absorbed into the body by means of the juices present in the gastrointestinal tract. D aily requirement of carbohydrate is 400 to 500 gram Sources of Carbohydrates A nimal source: example Honey, milk & milk products. V egetable source: example potato, fresh fruits, green vegetables , corn, rise, sugarcane etc. Functions: T hey are the main source of energy.
Protein P rotein are composed of carbon, hydrogen, Nitrogen Oxygen ,Phosphorus & Sulphur . Proteins are made from simple compound known as amino acids. T here are 24 amino acids which is needed by the body out of which 9 are essential amino acids. E ach protein can on oxidation is 4.1 Calories of energy. D aily requirement of protein for adult is 1 gram per kg of body weight .
1. Essential amino acids: There are 9 essential amino acids are present. Essential amino acids are those which are not synthesized in the body but are essential for the body growth and development . Ex: leucine , lysine, iso -lysine, methionine, Threonine, tryptophan, valine , histidine , phenylamine . 2. Non-essential amino acids : Non-essential amino acids are those which can be synthesized in the body. Ex: Alanine, Aspartic acid, Glycine, Glytenic acid, Proline , Cystine , Arginine, Aspargine , Aspartate, Serina , Thyrosine , Ornithine.
S ources of protein A nimal source: fish, eggs, milk, meat, cheese Vegetables Source: Nuts, soybean, cereals, pulses, Beans. F unctions U sed for growth and development of the body F or repair and maintenance of body tissue F or maintenance of osmotic pressure F or the synthesis of antibiotics enzymes hormones hemoglobin and coagulation factor Effect of protein deficiency T he deficiency of protein may leads to low birth weight, mentally retarded and undeveloped child. I n adults it may lead to loss of weight, increase in the susceptibility to the infection & delay in wound healing. Protein-energy malnutrition (PEM) is a common childhood disorder and is primarily caused by deficiency of energy, protein, and micronutrients . Kwashiorkor Maramus
fats F ats are composed of carbon, hydrogen and oxygen. T hey differ from carbohydrates that the percentage of oxygen is more in Carbohydrate than fat. S ome of the fats are liquid at room temperature Example: G roundnut oil, vegetable oil. Some of the fats are Semi solid at room temperature Example: butter, ghee F at is also a good source of heat and energy. The1 gram of Fat provide 4 Calories of energy. The fatty acids which cannot be synthesized in the body are known as essential fatty acid i t must be incorporated in diet Example: L inolic & linoleic acid, Lilolic & lilolinic acid
S ome of the fats which are synthesized in the body are known as non essential fatty acid Example: cholesterol and triglyceride S ources of fats: A nimal fat: example fish, milk, eggs, cheese butter Vegetable fats: example grains and vegetable oil F unctions of fat: T hey are the main source of energy and provide double energy. They provide support to the main organs of the body for example kidney, intestine, heart. Fatty layer below the skin plays an important role in maintaining the body temperature. F ats protect the body from external heat and cold.
effect of fat deficiency I n the deficiency of essential fatty acids may lead to rough and dry skin. Constipation Weakness Mood swings Increased susceptibility to infection Effect of excess fat in diet: It may also lead to increase in blood cholesterol level which may causes heart diseases. Obesity
minerals B ody has 24 mineral acids which are mainly absorbed from food, these minerals salts are very useful for maintenance and growth of body. T hey are classified into two major classes; M ajor minerals ex. calcium Phosphorus Sodium Potassium T race minerals ex. iodine, iron, zinc, fluorine Sources of minerals Vegetable sources: garlic, onion, green, vegetable A nimal sources: meat, eggs, milk
functions of minerals T hey maintain rigid structure of body such as a bone, teeth. T hey form a part of every cell T hey maintain tone and proper functions of muscles of body. They maintain electronic balance in the body fluid. T hey stimulate digestive secretions and are necessary for growth of the body.
Some important minerals are; 1. Potassium P otassium helps in maintaining the pH of the various body fluids also helps in contraction of muscles in transmission of nerve impulses. The daily requirement of potassium chloride varies is from 5 to 7 gram and excess is excreted through urine. Deficiency disorders of potassium: Hypokalemia V omiting Diarrhoea
2. calcium C alcium is the most common mineral present in human body. 99% of calcium is stored in the bones and teeth and remaining 1% is found in blood muscles and fluid between the cells. D eficiency disorders of calcium leads to osteoporosis
3. sodium Sodium the body needs a small amount of sodium to maintain the normal blood pressure and normal function of muscles and nerves D eficiency of sodium causes hyponatremia
4. iodine I t is an essential micronutrients. I t is required for synthesis of thyroid gland hormone for example thyroxine (T4) & tri iodothyroxine (T3) that contain 3 to 4 atoms of iodine. I t is needed for normal growth and development of body. H uman body contains 50 gram of iodine and blood level is about 8 to 12 microgram per liter. D eficiency of iodine may leads to Goiter(hypothyroidism), retarded physical development and mental function .
5. iron I t is necessary for formation of hemoglobin, brain development, regulation of body temperature. T he important function of iron is oxygen transport and cell respiration Deficiency of iron causes anemia
6. Zinc I t is the main component of many enzyme. I t is required for synthesis of insulin in pancreas. Deficiency: I ts deficiency causes retarded growth and skin disorders. 7. FLUORINE I t is necessary for normal mineralization of bones and formation of dental enamel . D eficiency inadequate intake of fluorine is associated with the dental caries
vitamins V itamins are the complex organic chemical substances, which are essential for normal growth and development of the body. T hey do not supply energy like fat and carbohydrate but they act as protective to the body against inhaled infection or disease. Classification of Vitamins T hey are classified into two major classes F at soluble vitamin: Ex. vitamin A D E and K Water soluble vitamin: Ex. vitamin B complex vitamin C
fat soluble vitamin 1. vitamin A I t is fat soluble vitamin and commonly known as Retinol. It is essential for integrating the epithelial cells throughout the body. I t is essential for new cell growth & visional purpose. It is anti infective and growth promoting vitamin D aily requirement for an adult is 5,000 units and for a growing children or pregnancy is varies from 6000 to 8000 Unit.
Sources of Vitamin A Animal source: example cod liver oil, butter ,Shark liver oil, ghee, Eggs. Vegetable source: carrot, cabbage, mango. Deficiency : I t causes night blindness it leads to retarded growth and resistance to the bacterial infection. It also causes anorexia ( Lack of sleep) & Xeropthalmia (whiteness of eyes), dryness of skin, respiratory infections like common cold. Anorexia
2. vitamin D I t is essential for the calcification of bones and teeth, there are two Pro vitamins of vitamin D known Ergosterol & 7-D-hydrocholesterol which are converted into vitamin D2 ( Ergocalciferol ) and Vitamin D3 ( cholecalciferol ) respectively. T his vitamin D present in UV sunlight S ources of vitamin D V egetables source: green vegetables Cauliflowers, cabbage, carrot. Animal sources: egg yolk, cod liver oil, Ghee D eficiency The deficiency of Vitamin D3 causes rickets and also causes dental caries. It also causes osteomalacia generally found in pregnant and lactating mother. rickets
3. Vitamin E Vitamin E is also known as tocopherol , which is stable to heat and light but it destroyed on oxidation. S ources of Vitamin E: beet, cereals and some vegetable oil Deficiency: I t causes anemia and neuromuscular disease in children.
4. vitamin K Is called Phytonadione . It is fat-soluble vitamin, which is stable to heat it is essential for formation of prothrombin and other blood clotting factors. I t is available in two form that is vitamin K1 and K2 vitamin. K 1naturally available in green vegetable and Vitamin K2 is available in fish milk Sources of vitamin K: I t is present in Green Leaves that is Spanish cauliflower, carrot D eficiency I ts deficiency leads to decrease in prothrombin formation and it causes prolongation of blood clotting that's why weakness, anemia occurs due to excessive blood loss.
water soluble vitamins 1. Vitamin B1 I t is known as thiamine . I t is soluble in water and alcohol but in soluble in fat. I t is essential for normal growth and development of body. Daily requirement is 2 milligram Sources: rice, pulses, nuts, cereals, fish, milk. Deficiency : Beri-beri , loss of appetite Beri-beri
2. vitamin B2 I t is known as riboflavin which is yellow pigment It is required for protein fats and carbohydrate metabolism. Daily requirement is 2 to 3 mg. S ources Milk, East, eggs, liver, green vegetable beet D eficiency I t leads to pellagra, diarrhoea , dermatitis, dementia. Pellagra Dementia
3. vitamin B3 I t is called as nicotinic acid. It a ct as coenzyme for fat protein and carbohydrate metabolism. Daily requirement is 12 to 18 milligram S ource Grains, cereals, meet, yeast, liver, green vegetables D eficiency it leads to weakness, mental depression
5. vitamin B5 I t is also called as pantothenic acid. I t is important in biosynthesis of corticosteroid. S ources : chicken, milk, fish, egg yolk, yeast, mushrooms, sweet potato and all grains. Deficiency: headache, fatigue, irritability, gastro-intestinal problems.
4. Vitamin B6 I t is known as pyridoxine . I t is exist in 3 form pyridoxine, pyridoxal , pyridoxy amine. I t is essential for metabolism of amino acid, fats and carbohydrates. Daily requirement is 2 milligram S ources I t is present in liver of fish, eggs, meat, wheat cereals and leafy vegetables. Deficiency I t deficiency leads to epilepsy.
6.vitamin B9 I t is important for synthesis of nucleic acid and also need for normal development of blood cells. S ources: Eggs, leafy green vegetables, beet, citrus fruits. Deficiency leads to anemia, diarrhea, dysentery, gastrointestinal disturbances.
7. vitamin B12 I t is known as Cynocobalamine due to the presence of cobalt. It is red crystalline and amorphous powder soluble in water. It is essential for Carbohydrate, protein, fat metabolism and RBC’s formation. S ources I t is found in animal source only, vegetable force does not contain Vitamin B12. Ex. liver, eggs, meat, milk Deficiency G enerally it is noticed that those patients who are strictly vegetarian leads to anemia, disturbance in DNA synthesis, and disturbance in carbohydrate fat and protein metabolism.
8. Vitamin C I t is also known as ascorbic acid. I t is water soluble vitamin which destroyed by exposure to air and heat. D aily requirement is 13 to 16 milligram Functions I t is essential for maintenance of cellular structure. I t is essential for formation of RBC’s. I t increases resistance of body to fight against infection. Sources M ain source of vitamin C are fresh fruits and vegetables like lemon, Orange, Cabbage, Cauliflower cereals. Amla is rich source of vitamin C. A nimal sources meet, milk, fish, eggs Deficiency leads to anemia, dental caries, loss of weight, delay in wound healing, bones become brittle.
Name of minerals Deficiency Disorder Potassium Hypokalemia, Vomiting Diarrhoea Calcium Osteoporosis (brittle Bones) Sodium Hyponatremia Iodine Gioter , hypothyroidism, retarded physical development and mental function Iron Anemia Zinc Retarded growth and skin disorders. Fluorins Dental caries
Vitamin Name of Vitamin Deficiency Disorder Vit . A Retinol Night Blindness , Xeropthalmia , Anorexia Vit . D Ergocalciferol , Cholecalciferol Rickets, Dental Caries, Osteomalacia Vit . E Tocopherol , Anaemia and Neuromuscular Disease Vit . K Phytonadione Anemia Vit . B1 Thiamine Beri-beri , Loss of Appetite Vit . B2 Riboflavin Pellagra, Diarrhoea , Dermatitis, Dementia Vit . B3 Nicotinic Acid. Weakness, Mental Depression
Vitamin Name of Vitamin Deficiency Disorder Vit . B5 Pantothenic Acid. Headache, Fatigue, Irritability, Gastro-intestinal Problems. Vit . B6 Pyridoxine Epilepsy. Vit . B12 Cynocobalamine Anemia, Disturbance in DNA Vit . C Ascorbic Acid. Dental Caries, Loss of Weight, Delay i n Wound Healing, Brittle Bones