3rd Line Of Defense

worst presentation on Immune System's 3rd Line Of Defense ever

1. Immune
System
Third Line of Defense
– Specific Immunity

2. called into action when
nonspecific methods are not
enough and infection becomes
widespread

3. FUNCTION
mounts attacks against
specific foreign substances
specific
foreign
substances

4. FEATURES………………

5. Self/non-self discrimination
- it normally distinguishes between self
and non-self and only reacts against
non-self.
n
o
n
-
s
e
lf

6. When a nonself (foreign) body
is detected, mitotic activity
in B and T lymphocytes is
stimulated

7. While mitosis is occurring, the
daughter populations become
subdivided into…

8. Effector cells
when fully differentiated,
they will seek and destroy
foreign materials

9. Memory cells
become dormant, but can be
triggered to rapid mitosis if
pathogen encountered again

10. Memory - it demonstrates memory. The
immune system "remembers" if it has seen
an antigen before and it reacts to
secondary exposures to an antigen in a
manner different than after a primary
exposure. Generally, only an exposure to the
same antigen will trigger this memory
response.

11. Specificity -
there is a high
degree of
specificity in its
reactions. A
response to a
particular antigen is
specific for that
antigen or a few
closely related
antigens.

13. CELLS
INVOLVED
………………

14. Macrophages
engulf foreign objects
inform T lymphocytes at a
specific antigen is present

15. Helper T cells
produce and secrete chemicals
which promote large numbers
of effector and memory cells

16. Cytotoxic T cell
T lymphocytes
that eliminate
infected body
cells and tumor
cells

17. B Cells
produce antibodies (secrete them
in the blood or position them on
their cell surfaces)

18. The process can
be simplified
into three
events:

19. (1) Recognition of a specific
invader
SPECIFIC INVADER

20. (2) Repeated cell divisions that
form huge lymphocyte
populations

21. (3) Differentiation into
subpopulations of effector
and memory cells
Effector Memory