Vaccination time (age of the child) Birth 6 th week 10 th wk 14 th week 9 months Vaccine(s) to be given BCG OPV0 OPV1 Penta PCV Rota Exactly like wk 6. Like wk 6, except no Rotavirus vaccine Measles Route Intradermal Oral Oral IM IM Oral SC Site Right deltoid Right thigh Left thigh Left Deltoid
Routes of Administration
Efficacy BCG – 80% for severe form of the disease; 0 - 80% for pulmonary TB. OPV – Sabin – 72% - 98% in hot climate. Lower protection against type III. Tetanus – >95%; 80% after 2 doses. Need booster q5 – 10yrs. Diphtheria >80% Pertussis – 80% for severe disease. Duration unknown. Rotarix – 90 – 100%.
No significant side effects for Tetanus vaccine Diphteria Hepatitis B
Licensed Rotavirus Vaccines Rotarix® RotaTeq® Safety = = Efficacy 90-100% severe 74-85% any severity 90-100% severe 74-85% any severity Antigen Monovalent HRV G1P[8] Pentavalent bovinehuman reassortant Schedule 2 doses 3 doses Protection against severe infx 2 years 2 years
Sensitivity BCG – Heat and light Tetanus and diphtheria – heat and freeze Pertussis – heat Measles – heat Polio – can be safely frozen and stay for decades