Indications for Mechanical Ventilation
UpperairwayobstructionandLower
airwayobstructionasaresultof
blockage.
Neuromusculardisordersasin
Myastheniagravis,Poliomyelitis,
Gullian-Barresyndrome,Snakebiteand
inadequatereversalofanesthesia.
6Prof. Dr. RS Mehta, BPKIHS
ContD…
Lung diseases which prevent proper
exchange of O
2and CO
2as in Chest Injuries
Pneumothorax, lung Infections, COPD,
Acute Respiratory Distress Syndrome
(ARDS).
Post-operative cardiac surgery, any other
surgery, shock & trauma.
Respiratory arrest.
7Prof. Dr. RS Mehta, BPKIHS
Criteria for institution of ventilator support:
Normal
range
(adult)
Ventilation
indicated
Parameters
10-20
5-7
65-75
75-100
> 35
< 5
< 15
<-20
A-Pulmonary function
studies:
•Respiratory rate
(breaths/min).
•Tidal volume (ml/kg
body wt)
•Vital capacity (ml/kg
body wt)
•Maximum Inspiratory
Force (cm H
2O) 8Prof. Dr. RS Mehta, BPKIHS
Criteria for institution of ventilatorysupport:
Normal
range
Ventilation
indicated
Parameters
7.35-7.45
75-100
35-45
< 7.25
< 60
> 50
B-Arterial blood
Gases
•PH
•PaO
2(mmHg)
•PaCO
2(mmHg)
9Prof. Dr. RS Mehta, BPKIHS
Classification of Ventilators
Ventilator
Positive pressure Negative pressure
10Prof. Dr. RS Mehta, BPKIHS
Origins of mechanical ventilation
•Negative-pressure ventilators
(“iron lungs”)
•Non-invasive ventilation first
used in Boston Children’s
Hospital in 1928
•Used extensively during polio
outbreaks in 1940s –1950s
•Positive-pressure ventilators
•Invasive ventilation first used at
Massachusetts General Hospital
in 1955
•Now the modern standard of
mechanical ventilation
The era of intensive care medicine began with positive-pressure ventilation
The iron lung created negative pressure in abdomen
as well as the chest, decreasing cardiac output.
Iron lung polio ward at Rancho Los Amigos Hospital
in 1953.
18Prof. Dr. RS Mehta, BPKIHS
Mechanical Ventilators Classification
19Prof. Dr. RS Mehta, BPKIHS
2.Cycling
how the ventilator switches from inspiration to
expiration
Time, flow, volume & pressure cycling
mechanism.
Timecycled:
-is terminated to the expiratory phase once a
predetermined inspiratory time elapses
-it is used for neonates and in the operating
room
21Prof. Dr. RS Mehta, BPKIHS
Volume cycled:
Terminate in inspiration when a preselected
volume is delivered.
Many adult ventilators are volume cycled but
also have secondary limits on inspiratory
pressure to guard against pulmonary
barotrauma.
If inspiratory pressure exceeds the pressure
limit, the machine cycles into expiration even
if the selected volume has not been delivered.
23Prof. Dr. RS Mehta, BPKIHS
INTERMITTENTMANDATORY VENTILATION (IMV)
A mode of mechanical ventilation in
which the patient is allowed to breathe
independently except during certain
prescribed intervals, when a ventilator
delivers a breath either under positive
pressure or in a measured volume.
32Prof. Dr. RS Mehta, BPKIHS
ASSIST CONTROL VENTILATION
This mode is used for pts. who can initiate a breath but
who have weakened respiratory muscles.
In this mode, the ventilator provides a mechanical breath
with either a pre-set tidal volume or peak pressure every
time the pt. initiates a breath.
If the pt. fail to initiate inspiration, the ventilator
automatically goes into the back up mode and delivers
the pre set rate and tidal volume until it senses an
inspiratory effort.
It is used in disease conditions like Myasthenia gravis,
GB syndrome, post cardiac/respiratory arrest, pulmonary
edema, ARDS, etc.
36Prof. Dr. RS Mehta, BPKIHS
INVERSE RATIO VENTILATION (IRV)
Thenormalinspiratory:expiratoryratio
is1:2,butthisisreversedduringIRVto
2:1orgreater(themaximumis4:1).
Thismethodisusedforpatientswhoare
stillhypoxic,evenwiththeuseofPEEP.
37Prof. Dr. RS Mehta, BPKIHS
Time Cycled Ventilators
Time-cycledventilatorsterminateor
controlinspirationafterapre-settime.
Theseventilatorsareusedinnewborn&
infants.
39Prof. Dr. RS Mehta, BPKIHS
There are several ventilation modes, the most important are:Summary
Controlled Mechanical Ventilation (CMV)
-Pressure Controlled Ventilation (PCV)
-Volume Controlled Ventilation (VCV)
Intermittent Positive Pressure Ventilation
(IPPV)
Pressure Support Ventilation (PSV)
Synchronized Intermittent Mandatory
Ventilation (SIMV)
Bi-level Positive Airway Pressure (BIPAP)
Continuous positive airway pressure (CPAP)
Inverse Ratio Ventilation (IRV)
40
Prof. Dr. RS Mehta, BPKIHS
Summary…
Pressure-cycled modes
•Pressure Support Ventilation (PSV)
•Pressure Control Ventilation (PCV)
•CPAP
•BiPAP
Volume-cycled modes
•Assist/Control
•Intermittent Mandatory Ventilation (IMV)
•Synchronous Intermittent Mandatory
Ventilation (SIMV)
41
Prof. Dr. RS Mehta, BPKIHS
Initiating Mechanical Ventilation
Initial ventilator settings:
FiO
2 1.0 initially but then reduce
PEEP 5 -7 cmH
2O
Tidal volume 7-10 ml/kg
Inspiratory pressure 20 cmH
2O (15cmH
2O above PEEP)
Frequency 10 -15 breaths per minute
Pressure support (ASB) 20 cmH
2O (15cmH
2O above PEEP)
I:E Ratio 1:2
Flow trigger 2 l/min
Pressure trigger -1 to -3 cmH
2O
Inspiratory flow 60 L/min
**These settings should be titrated against the pt.'s clinical
state and level of comfort.
42Prof. Dr. RS Mehta, BPKIHS
43Prof. Dr. RS Mehta, BPKIHS
Indications for intubation
•Criteria
•Clinical deterioration
•Tachypnea: RR >35
•Hypoxia: pO2<60mm Hg
•Hypercarbia: pCO2 > 55mm Hg
•Minute ventilation<10 L/min
•Tidal volume <5-10 ml/kg
•Negative inspiratoryforce <
25cm H2O (how strong the pt
can suck in)
•Initial vent settings
•FiO
2= 50%
•PEEP = 5cm H
2O
•RR = 12 –15 breaths/min
•V
T= 10 –12 ml/kg
•COPD = 10 ml/kg (prevent over-
inflation)
•ARDS = 8 ml/kg (prevent volu-trauma)
•Permissive hyper-capnea
•Pressure Support = 10cm H
2O
How the values trend should significantly impact clinical decisions
44Prof. Dr. RS Mehta, BPKIHS
Indications for extubation
•Clinical parameters
•Resolution/Stabilization of
disease process
•Hemodynamicallystable
•Intact cough/gag reflex
•Spontaneous respirations
•Acceptable vent settings
•FiO
2< 50%, PEEP < 8, P
aO
2
> 75, pH > 7.25
•General approaches
•SIMV Weaning
•Pressure Support Ventilation
(PSV) Weaning
•Spontaneous breathing trials
and use of T-piece
•Demonstrated to be superior
No weaning parameter completely accurate when used alone
Numerical
Parameters
Normal
Range
Weaning
Threshold
P/F > 400 > 200
Tidal volume 5 -7 ml/kg 5 ml/kg
Respiratory rate 14 -18 breaths/min< 40 breaths/min
Vital capacity 65 -75 ml/kg 10 ml/kg
Minute volume 5 -7 L/min < 10 L/min
Greater Predictive
Value
Normal
Range
Weaning
Threshold
NIF (Negative
InspiratoryForce)
> -90 cm H2O > -25 cm H2O
RSBI (Rapid
Shallow Breathing
Index) (RR/TV)
< 50 < 100
Marino P,The ICU Book (2/e). 1998.
45Prof. Dr. RS Mehta, BPKIHS
Spontaneous Breathing Trials
•Settings
•PEEP = 5, PS = 0 –5, FiO
2< 40%
•Breathe independently for 30 –
120 min
•ABG obtained at end of SBT
•Failed SBT Criteria
•RR > 35 for >5 min
•S
aO
2<90% for >30 sec
•HR > 140
•Systolic BP > 180 or < 90mm Hg
•Sustained increased work of
breathing
•Cardiac dysrhythmia
•pH < 7.32
SBTs do not guarantee that airway is stable or pt can self-clear secretions
Causes of Failed
SBTs
Treatments
Anxiety/Agitation Benzodiazepines or haldol
Infection Diagnosis and tx
Electrolyte abnormalities
(K
+
, PO
4-
)
Correction
Pulmonary edema, cardiac
ischemia
Diuretics and nitrates
Deconditioning,
malnutrition
Aggressive nutrition
Neuromuscular disease Bronchopulmonary hygiene,
early consideration of trach
Increased intra-abdominal
pressure
Semirecumbentpositioning,
NGT
Hypothyroidism Thyroid replacement
Excessive auto-PEEP
(COPD, asthma)
Bronchodilator therapy
Senaet al, ACS Surgery: Principles and
Practice (2005).
46
Prof. Dr. RS Mehta, BPKIHS
Guidelines Suggesting the Need for Mechanical Ventilation
Parametersthathelpustoguidetotakethedecision
whethermechanicalventilationisneededornot?
1.Cl.Indices:
Apneawithrespiratoryarrest
RR>35breathsperminute
Paralysisofbreathingmuscle-GBS,MG
headtrauma,coma
-anabsentgagorcoughreflex.
-Effectofanestheticandmusclerelaxant
-Others:shock,CCF,sepsis
47
Prof. Dr. RS Mehta, BPKIHS
2. Mechanical indices
Vital capacity <15 mL/kg
Tidal volume <5 mL/ kg
Maximum inspiratoryforce < –25 cm H
2O
3. Respiratory gas tensions
Direct indices
PaO
2(<60 mm Hg)
PaCO
2(>50 mm Hg with pH <7.25)
Derived indices
PaO
2/FIO
2ratio < 300 mm Hg
48
Prof. Dr. RS Mehta, BPKIHS
S.NComponents Values
1.Respiratory rate>35-40/min
2.Tidal capacity < 10-15 ml/kg
3.PaO2 <60-70 mmHg under
O2 therapy
4.PaCO2 >50-55mmHg
5.Inspiratorypressure>20-25 cm H2O
49Prof. Dr. RS Mehta, BPKIHS
VENTILATOR ALARMS
ALARM DEFINITION POTENTIALCAUSE
1. High
pressure
•Pressure required to ventilate
exceeds preset pressure
Pneumothorax, excessive
secretions, decreased lung
compliance.
2.Low pressure•Resistanceto inspiratory flow is
less than preset pressure.
Disconnected from ventilator,
breakin circuit.
3.Low exhaled
volume
•Exhaled tidal volume drops
belowpreset amount.
Leak in system, increased
airway resistance, decreased
lung compliance
4.Rate /apnea•Respiratory rate drops below
preset level. Apnea period
exceeds set time
Clientfatigue, decreased R.R
due to medication.
5.FIO2 •Indicates FIO2 driftfrom preset
range.
Changein level of
consciousness, disconnected
from O2 source, break in
circuit.
50Prof. Dr. RS Mehta, BPKIHS
COMPLICATIONS OF MECHANICAL
VENTILATION
I.Complication associated with patient’s
response to mechanical ventilation .
II.Complication associated to ventilator
malfunction.
III.Complications related to endotracheal
intubation.
51Prof. Dr. RS Mehta, BPKIHS
Complication associated with patient’s
response to mechanical ventilation
1.Decreased cardiac output.
2.Decreased renal perfusion.
3.Positive water balance.
4.Barotraumas.
5.Nosocomial pneumonia.
52Prof. Dr. RS Mehta, BPKIHS
Complicationassociatedtoventilator
malfunction
1. Alarms turned off or non-functional
–may lead to apnea and respiratory
arrest.
2. Low exhaled volume.
53Prof. Dr. RS Mehta, BPKIHS
Complications related to
endotrachealintubation
1.Sinusitis and nasal injury
2.Tracheoesophagealfistula
3.Laryngeal or tracheal stenosis
4.Cricoidabscess
54Prof. Dr. RS Mehta, BPKIHS
NURSINGCARE OF PATIENTS ON VENTILATOR
PHYSIOLOGICAL NEEDS:
comfort
activity
nutrition
elimination of wastes
Patients are often not able to fulfill these needs by
themselves, nursing function is then for example
seeing to comfort, determining intake and output
together with blood chemistry to assess adequacy of
intravenous nutrition, and so on.
55Prof. Dr. RS Mehta, BPKIHS
CONTD..
NEED TO KNOW AND UNDERSTAND:
Need for knowledge and comprehension
An explanation of diagnosis and treatment on the
patient’s level.
SELF ACTUALIZATION:
Order, truth, privacy
Patients should have as much privacy as possible —
pull screens or close doors. The patient has the right to
be told the truth.
58Prof. Dr. RS Mehta, BPKIHS
Nursing Diagnoses
Ineffective breathing pattern
Potential for pulmonary infection
Impaired water and fluid regulation
Oral hygiene
Potential altered nutritional status: less than body
requirement related to NPO status
Potential for complications related to immobility
59Prof. Dr. RS Mehta, BPKIHS
Nursing Diagnoses…
Knowledge deficit related to intubation and
mechanical ventilation
Elimination care
Promoting coping ability
Preventing trauma and infections
Promoting rest and sleep
Safety and security needs.
60Prof. Dr. RS Mehta, BPKIHS
Criteria for weaning
Tidal volume be above a given threshold
(greater than 5 ml/kg),
Respiratory frequency be below a given
count (less than 30 breaths/min),
Oxygen partial pressurebe above a given
threshold (PaO2 greater than 60mm Hg) and
FIO2<40%
Vital capacity 10 to 15 ml/kg.
64Prof. Dr. RS Mehta, BPKIHS
Since weaning is the graded removal of a
therapeutic modality, the sudden withdrawal
will not be tolerated.
So, weaning from the following 5 modalities
should be independently assessed.
1.Supplemental oxygen
2.PEEP
3.Mechanical ventilation
4.Artificial airway
5.Ionotrops
65Prof. Dr. RS Mehta, BPKIHS
Methods of Weaning
1-T-piece trial,
2-Continuous Positive Airway Pressure (CPAP)
weaning,
3-Synchronized Intermittent Mandatory Ventilation
(SIMV) weaning,
4-Pressure Support Ventilation (PSV) weaning.
66Prof. Dr. RS Mehta, BPKIHS
Signs of Weaning Intolerance Criteria
Diaphoresis
Dyspnoea& Labored respiratory pattern
Increased anxiety, Restlessness, Decrease in
level of consciousness
Dysrhythmia, Increase or decrease in heart rate
of > 20 beats /min. or heart rate > 110 b/m,
Sustained heart rate >20% higher or lower than
baseline
67Prof. Dr. RS Mehta, BPKIHS
Criteria…
Increase or decrease in blood pressure of > 20 mm Hg
Systolic blood pressure >180 mm Hg or <90 mm Hg
Increase in respiratory rate of > 10 above baseline or >
30
Sustained respiratory rate greater than 35
breaths/minute
Tidal volume ≤5 ml/kg, Sustained minute ventilation
<200 ml/kg/minute
SpO2 < 90%, PaO2 < 60 mmHg, decrease in PH of <
7.35.
Increase in PaCO
2.
68Prof. Dr. RS Mehta, BPKIHS
NURSING CARE OF THE PATIENT BEING WEANED
Assesstheclientfortheweaningcriteria.
Monitortheactivitylevel,assessdietaryintakeand
monitorresultsofthelabtests.
Assessclient’s&family’slevelofunderstandingof
weaning.
Explainthatpatientmayfeelshortnessofbreath
initially&provideencouragementasneeded.
Monitorvitalsigns,pulseoximetry,ECGchanges,
ABGanalysis&respiratorypatterncontinuouslyfor
thefirst20-30min&thenevery5minuntilweaning
iscomplete.
69Prof. Dr. RS Mehta, BPKIHS
Nursing Care…
Implement the weaning method prescribed: ASB,
IMV, SIMV, CPAP, T-piece, etc….
Maintain a patent airway, suction the airway as
needed.
Monitor the ABG level & Pulmonary Function Test
as per requirement.
Terminate the weaning if adverse reactions occur.
Assess psychological dependence if the physiologic
parameters indicate weaning is feasible or patient
still resists.
70Prof. Dr. RS Mehta, BPKIHS
Elimination Care:
Catheter care
Proper cleaning, use of bed pan if
possible.
Optimal Level of Mobility:
The nurse should help active or passive
range of motion every 6-8 hours to
prevent contractures and venous stasis.
71Prof. Dr. RS Mehta, BPKIHS
Promoting Optimal Communication:
Assessment of the ability of the ventilator-
dependent patient's to communicate and thus
identify the patient's limitations.
Use non-verbal methods of communication.
Use of signals, signs, nodding, palm writing, lip
reading.
Provide paper & pencil, magic slate.
Be alert to non-verbal clues.
Allow patient to respond and repeat
explanations.
72Prof. Dr. RS Mehta, BPKIHS
Preventing trauma and infections:
Positioning of the ventilator tubing
should be such that there is minimal
pulling or distortion of the tube in the
trachea to reduce the risk of trauma to
the trachea.
Monitoring of cuff pressure every 8 hrs
to maintain the pressure less than 25cm
of H2O.
Tracheotomy care at least every 8
hourly & more frequent if need.
73Prof. Dr. RS Mehta, BPKIHS
Preventing trauma and infections…
Oral care frequently because the oral cavity is
the primary source of contamination of the
lungs in the intubatedand compromised
patients.
The naso-gastric tube can increase the risk
of aspiration, leading to nosocomial
pneumonia hence the patient should be
positioned with the head elevated above the
stomach.
All prescribed medications should be given on
time.
Prof. Dr. RS Mehta, BPKIHS 74
Promoting coping Ability:
Encouraging family to verbalize their
feelings about the ventilators, patient's
condition is beneficial.
Explanation about the procedures every
time they are performed helps to reduce
anxiety.
75Prof. Dr. RS Mehta, BPKIHS
Rest & Sleep:
Keep calm & quiet environment.
Turn monitor alarm down if possible.
Provide dim light during night & soft music
if possible.
Cover patient eyes with clean gauze.
76Prof. Dr. RS Mehta, BPKIHS
Oral Hygiene:
Provide oral care every 2 hourly as oral mucus
membranes dry in 2 hours.
Moisten the mouth with solutions that do not
contain alcohol or lemon. Moistens the lips with
lubricant. It prevents drying, cracking &
excoriation.
Brush the client’s teeth as twice daily as dental
caries are prevented by saliva.
Suction oral secretions from the mouth as
secretions pool in oro-pharynx because of the
inflated tracheal cuff.
Assess for pressure areas at the corner of the
mouth.
77Prof. Dr. RS Mehta, BPKIHS
SAFETY & SECURITY NEEDS
Secure physically, mentally, emotionally.
Prevent trauma & infection
Perform hand-hygiene & adopt sterile
techniques.
Prevention of cross-infection & nosocomial
infection.
Maintain warm & adequate body temperature.
Put side-rails.
Visiting hours should be defined.
78Prof. Dr. RS Mehta, BPKIHS
ARTIFICIAL AIRWAY:
1.COMBITUBE.
2.LMA (Laryngeal Mask Airway)
3.OROPHARYNGEAL airway
4.NASOPHARYNGEAL airway
5.ETT
6.TRACHEOSOTOMY tube.
79
Prof. Dr. RS Mehta, BPKIHS