INTRODUCTION Arterial Blood Gas pH P a CO 2 P a O 2
INTRODUCTION Arterial Blood Gas pH P a CO 2 P a O 2 HCO 3 - O 2 saturation
INTRODUCTION
INTRODUCTION
INTRODUCTION
INTRODUCTION Measured/Calculated
ACID BASE BALANCE
ACID BASE BALANCE Clinical consequence of dysregulation of Acid Base balance Poor vascular tone Myocardial pump failure Risk of arrythmias Skeletal muscle weakness Electrolyte abnormalities Delirium/Coma Impaired cellular respiration
ACID BASE BALANCE Net acid production equals net acid elimination Three stages Acid is produced as a consequence of normal metabolism Acid is transported via blood Acid is eliminated via lungs and kidneys
ACID BASE BALANCE
ACID BASE BALANCE
ACID BASE BALANCE Intravascular transport of acids To prevent sudden and large swings in pH buffers are necessary Buffers have two main characteristics
ACID BASE BALANCE HCO 3 - /CO 2 Buffering system
ACID BASE BALANCE HCO 3 - /CO 2 Buffering system
ACID BASE BALANCE Other physiological buffers
ACID BASE BALANCE Hendersen-Hasselbach Equation
ACID BASE BALANCE
ACID BASE BALANCE
ACID BASE BALANCE
ACID BASE BALANCE
ACID BASE BALANCE
ACID BASE BALANCE
ACID BASE BALANCE
SIMPLE ACID BASE DISORDERS
SIMPLE ACID BASE DISORDERS
SIMPLE ACID BASE DISORDERS
SIMPLE ACID BASE DISORDERS
SIMPLE ACID BASE DISORDERS
SIMPLE ACID BASE DISORDERS
SIMPLE ACID BASE DISORDERS Step 1 Always start with the pH
SIMPLE ACID BASE DISORDERS Step 2 Check the P a CO 2