Afatinib Tablet for lung cancer Treatment

This presentation covers all the essential details about Afatinib tablets — including its uses in lung cancer treatment, dosage guidelines, and possible side effects. It also highlights the latest Afatinib price in the Philippines and how this targeted therapy helps patients with EGFR-positive NSCLC. You can also check how to buy Afanat tablets online in cities like Manila, Cebu through trusted sources such as LetsMeds. Learn More: https://www.letsmeds.com/afatinib-tablets-price-philppines

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Afatinib: A Targeted Therapy for Non-
Small Cell Lung Cancer

Understanding an Effective Treatment Option for EGFR Mutation-Positive NSCLC

A comprehensive overview of Afatinib's mechanism, availability, dosage, and benefits for lung cancer patients

2. What is Afatinib?

- Targeted therapy medicine
- Tyrosine kinase inhibitor (TKI)
- Blocks cancer cell growth

- Mechanism of action

Dosage Information

- Standard dosing regimen
- Administration guidelines
- Timing with meals

- Dosage adjustments

Table of Contents

Brand Names &

Availability

- Common brand: Afanat
- Available strengths

- Manufacturers

- Availability in Philippines

Side Effects

- Common side effects

- Serious adverse reactions
- Management strategies

- When to consult a doctor

Uses of Afatinib

- EGFR mutation-positive NSCLC
- Metastatic stage cancer

- Alternative to other TKIs

- Clinical benefits

Accessing Afatinib

- Price considerations

- How to purchase online
- LetsMeds service

- Support resources

3. What is Afatinib?

A Targeted Therapy for Lung Cancer

Afatinib is a specialized medication designed to treat
non-small cell lung cancer (NSCLC). It works by
targeting specific molecular pathways involved in
cancer growth, offering a more precise approach than
traditional chemotherapy.

Mechanism of Action

- Belongs to tyrosine kinase inhibitor (TKI) class
- Specifically targets EGFR mutations

- Covalently binds to cysteine 797 of the epidermal growth
factor receptor

- Blocks signaling pathways that promote tumor cell growth
- Prevents cancer cells from dividing and spreading

Clinical Significance

- Approved for treatment of EGFR mutation-positive NSCLC
- Demonstrates improved progression-free survival

- Effective against certain resistant mutations

- Shows activity against brain metastases

- Represents an important advancement in precision
medicine

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Product Information

- Available as Afanat 30 mg and 40 mg tablets

- Manufactured by Natco Pharma and other Indian
pharmaceutical companies

- Film-coated tablets for oral administration

- Packaged in blister packs for protection

Accessing Afatinib Treatment

Afatinib is marketed under various brand names
globally, with Afanat being a common brand in the
Philippines and other Asian markets. This medication
represents an important treatment option for patients
with specific genetic mutations in their lung cancer.

Distribution Channels

- Available through trusted online sources like
LetsMeds

- Accessible in major Philippine cities including
Manila, Cebu, and Davao

- Requires valid prescription from oncologist

- Generic versions offer more affordable alternatives

5. Uses of Afatinib

Primary Indication

- First-line treatment for EGFR
mutation-positive non-small cell lung
cancer (NSCLC)

- Specifically effective for exon 19
deletions or exon 21 substitution
mutations

- Demonstrated superior progression-
free survival compared to
chemotherapy

- Approved for advanced or metastatic
disease

- Shows activity against certain
resistant mutations

- Targets cancer at the molecular level

Patient Selection

- Prescribed for patients with
confirmed EGFR mutations

- Used when cancer has spread
(metastatic stage)

- Most effective in specific genetic
profiles

- May be recommended for
patients who cannot tolerate
chemotherapy

- Genetic testing required before
starting treatment

- Consideration of patient's
overall health status

Alternative Treatment

- Option when other EGFR
inhibitors (Gefitinib or Erlotinib)
stop working

- May overcome resistance to first-
generation TKIs

- Can be used in combination
therapies in certain cases

- Shows activity against uncommon,
EGFR mutations

- Alternative for patients with brain
metastases

- Part of sequential treatment
strategies

6. Dosage Information

Standard Dosing

- Typical starting dose: 40 mg once
daily

- Alternative starting dose: 30 mg
once daily

- Continuous daily administration
- Treatment continues until disease
progression

- Tablets should be swallowed
whole with water

- Long-term therapy requiring
regular monitoring

- Consistent timing each day
improves efficacy

Administration Guidelines

- Take at least 1 hour before meals
- Or take at least 2 hours after
eating

- Avoid grapefruit products
during treatment

- Store at room temperature away
from moisture

- Do not crush or break tablets

- Take missed doses as soon as
remembered

- Skip if close to next scheduled
dose

Dosage Adjustments

- Dosage may be reduced for side
effect management

- Common step-down: 40 mg to 30 mg
1020 mg

- Temporary interruptions may be
necessary

- Adjustments based on individual
tolerance

-Liver or kidney impairment may
require dose modification

- Doctor's guidance essential for any
dosage changes

- Regular assessment determines
optimal dosing

7. Common Side Effects

Diarrhea

- Occurs in many patients taking Afatinib
- Can range from mild to severe

- May require anti-diarrheal medications
- Usually appears within first few weeks
- Report to doctor if severe or persistent

Skin Rash or Acne

- Appears as acne-like eruptions
- Often affects face, chest, and back

- Can be itchy and uncomfortable

- May require topical treatments

- Usually improves with continued use

Mouth Sores

- Painful ulcers in mouth and throat
- Can make eating and drinking difficult

- May require special mouthwashes

- Good oral hygiene helps prevent severity
- Report if unable to eat or drink

Other Side Effects

- Loss of appetite leading to weight loss
- Fatigue and general weakness

- Nail changes or inflammation

- Dry skin and itching

- Consult doctor if side effects worsen

8. Serious Side Effects

Liver Problems

Breathing Difficulties

Eye Irritation

- Yellowing of skin

- Abdominal pain

- Dark urine

- Nausea/vomiting

- Requires immediate
medical attention

- Doctor may adjust
dosage

- Sudden shortness
of breath

- Chest pain

- Coughing

- Fever

- May indicate lung
inflammation

- Seek medical help

- Redness or pain
- Vision changes

- Sensitivity to
light

- Excessive tearing
- May require eye
drops

- Report symptoms

9. Afatinib Price in Philippines

Price Variations

- Varies by brand
- Supplier pricing
- Package size
- Dosage strength
- Import costs
- Pharmacy markup

Generic Options

- Afanat 30mg
- Afanat 40mg

- More affordable
- Same efficacy
- Indian-made

- Quality assured

Availability

-Manila
-Cebu
-Davao
- Quezon City
- Makati
- Other cities

Cost Factors

- Brand name
- Generic vs original
- Quantity purchased
-Shipping costs
- Import duties
- Prescription status

10. How to Buy Afanat Online

Visit LetsMeds Website

- Go to www.letsmeds.com

Check availability for Afatinib 30mg/40mg
- Browse product information and pricing
- Free medicine consultation available

Contact Options

- Call/WhatsApp: [phone]

- Email: [email protected]
=$: - Fast delivery across the Philippines

- Secure payment options available

11. Quality Assurance

- Trusted supplier for Indian generic medicines
- All products sourced from reputable
pharmaceutical manufacturers

- Genuine Afatinib tablets with proper
packaging and documentation

- Quality control measures in place

Customer Benefits

- Affordable prices compared to local options
- Fast and secure delivery across Philippines
- Personalized customer support before

and after purchase

- Assistance with medication information

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Thank You

Visit: www.letsmeds.com
| ; b Call/WhatsApp: [phone]

Email: [email protected]