Analeptics

Analeptics

1. Analeptics

Presented By:Sweety gupta CM PHARM, Pharuacology )

SANJEEVINI SCHOOL OF PHARMACY
VIJAYAPUR

2. *Analeptics -

“These are the C.N.S stimulants. They increase
the activity of various parts of central nervous
system (brain and spinal cord ). They are used
reduce the depression.

3. . Naturally occurring drugs- Caffeine ,
theophylline

. Synthetic drugs- Nikethamide ( Coramine )

Miscellaneous - Dextro-amphetamine .

4. Theophylli

- Physical properties -

|. White crystalline powder.

2. Odourless and has bitter taste
3. Slightly soluble in water:

“Stability and storage condition- It is stored in
well closed containers

5. “Uses -

. It is used as bronchodilator ( respiratory
stimulant )

. It has slight stimulant action.
It is cardiac stimulant

a ca

6. Popular brand names- Theograd, Unikon

7. - Caffeine-

"Structure -

Nomenclature- 1,3,7-trimethyl xanthine

8. "Physical properties -

I. White crystalline powder

2. Odourless and has bitter taste.
3. Sparingly soluble in water

-Stability and storage condition- It is stored in
tightly closed containers. Label should bear
whether it is anhydrous or monohydrate .

9. “Uses -

I. It is CNS stimulant

2. It is cardiac stimulant.
3

It is respiratory stimulant

10. "Popular brand names- Excedrin

ae DRIN.

11. *Coramine- ( Nikethimide ) -
*Structure-

Nomenclature- N, N-diethyl, pyridine-3-
carboxamide

12. "Physical properties -

I. Colourless and slight yellow crystalline powder
2. Faint aromatic odour and has bitter taste

3. Cause burning sensation on the tongue

4. It is miscible with water. alcohol and ether.

"Stability and storage condition- It is stored in
tightly closed, light resistant containers.

13. “Uses -
I. It is CNS stimulant

14. "Popular brand names- Nikethacure, Trinkmide

15. * Dextro-amphetamine -
“Physical properties-

I. White crystalline powder

2. Odourless and has bitter taste

3. Soluble in water

Stability and storage condition- It is stored in
tightly closed, light resistant containers.

16. “Uses -
I. It is CNS stimulant

17. "Popular brand names- Dexedrine

Dexedrine oy

18. Assignment Questions-

Write the structure and use (Im. 2016) of Coramine (Im.

2020 )

Classify Analeptics with examples. (5m. 2020)

Give structure and uses.of Caffeine’ (2m. 2017 )

Write the structure. chemical name and uses of caffeine

and imipramine. (6m, 2018 )
5. Define and classify Analeptics with examples. Write the
structure, nomenclature, physical properties. stability and
storage conditions, uses and brand names of Caffeine and
Coramine

19. “END OF THE CHAPTER-

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ank You