What are the Functions
of the Skeletal System?
1. Support. The skeleton serves
as the structural
framework for the body by
supporting soft tissues
and providing
attachment
points for the tendons
of most skeletal
muscles.
2. Assistance in movement.
Most skeletal muscles
attach to bones; when
they contract, they pull on
bones to produce
movement.
Muscle attached to bones!!
What are the
Functions of the
Skeletal System?
3. Protection. The skeleton
protects the most
important internal
organs from injury.
4. Blood cell formation.
A connective tissue
called red bone
marrow produces red
blood cells, white
blood cells, and
platelets, a process
called
hematopoiesis.
What are the
Functions of the
Skeletal System?
5. Storage: Bones store
minerals, such as
calcium and
phosphorus, for
use by the body
6. Triglyceride storage.
Yellow bone marrow
consists mainly of
adipose cells, which
store triglycerides. The
stored triglycerides
are a potential
chemical energy
reserve.
The Skeletal System
Parts of the skeletal system
Bones (skeleton)
Joints
Cartilages
Ligaments
Tendons
Two subdivisions of the skeleton
1.Axial skeleton
2.Appendicular skeleton
Bones of the Human Body
The skeleton has 206 bones
Two basic types of bone tissue
Compact bone
Dense and looks smooth
Homogeneous
Spongy bone
Small needle-like
pieces of bone
Many open spaces
Classification of Bones
►Long bones
Typically longer than they
are wide
Shaft with heads situated
at both ends
Contain mostly compact
bone
Long bones, especially
the femur and tibia, are
subjected to most of the
load during daily activities
and they are crucial for
skeletal mobility.
Classification of Bones
►Short bones
Generally cube-shaped or
they are as wide as they
are long
Contain mostly spongy
bone
Includes bones of the
wrist and ankle
Sesamoid bones are a type
of short bone which form
within tendons (patella)
Primary function is to
provide support and
stability with little to no
movement.
Classification of Bones
►Flat bones
Thin, flattened, and
usually curved or are
expanded into broad.
Two thin layers of
compact bone surround a
layer of spongy bone
principal function is either
extensive protection or the
provision of broad surfaces
for muscular attachment.
Classification of Bones
►Irregular bones
Irregular shape
Do not fit into other
bone classification
categories
Classification of Bones
►Sesamoid bones
shaped like a sesame seed
develop in certain tendons or a small nodular
bone most often present embedded in tendons
where there is considerable friction, tension,
and physical stress, such as the palms and
soles.
Classification of Bones
How Strong are
Bones?
The structure of
bones make it
both strong and
light weight.
20 % of an adults
body weight is
bone.
Bone is made up
of 2 minerals:
►Calcium
►Phosphorus
Diaphysis (shaft)
Makes up most of
bone’s length
Composed of compact
bone
Epiphysis (ends)
Composed mostly of
spongy bone enclosed
by thin layer of compact
bone
Anatomy of a Long Bone
Articular
cartilage
Spongy bone
Epiphyseal
line
Periosteum
Compact bone
Medullary
cavity (lined
by endosteum)
Proximal
epiphysis
Diaphysis
Distal
epiphysis
Articular cartilage
Covers the external
surface of the epiphyses
Made of hyaline cartilage
Decreases friction at joint
surfaces
Periosteum
Outside covering of the
diaphysis
Fibrous connective tissue
membrane
Perforating (Sharpey’s)
fibers secure periosteum
to underlying bone
Anatomy of a Long Bone
Epiphyseal line
Remnant of the
epiphyseal plate
Seen in adult bones
Epiphyseal plate
Flat plate of hyaline
cartilage seen in
young, growing bone
Causes lengthwise
growth of a long bone
Articular
cartilage
Spongy bone
Epiphyseal
line
Periosteum
Compact bone
Medullary
cavity (lined
by endosteum)
Proximal
epiphysis
Diaphysis
Distal
epiphysis
Anatomy of a Long Bone
Anatomy of a Long Bone
Endosteum
Lines the inner surface of the
shaft
Made of connective tissue
Structure of Bone
Microscopic anatomy
of compact bone
Osteocytes
Mature bone cells
situated in bone
matrix
Lacunae
Cavities in bone
matrix that house
osteocytes
Lamellae
Concentric circles of lacunae situated around the
central (Haversian) canal
Structure of Bone
Central (Haversian)
canal
Opening in the
center of an osteon
(Haversian system)
Runs lengthwise
through bone
Carries blood
vessels and nerves
Osteon (Haversian system)
A unit of bone containing central canal and matrix rings
Structural and functional unit of compact bone
Structure of Bone
Canaliculi
Tiny canals
Radiate from the central canal to lacunae
Form a transport system connecting all bone cells to a
nutrient supply
How Do Bones
Develop?
As an infant, most of your
skeleton is cartilage.
Cartilage is a strong
flexible tissue.
Over time the cartilage is
replaced by solid bone,
usually complete by the
time you stop growing.
Not all cartilage is
replaced in adults. Many
joints contain cartilage,
protecting the ends of
bones (ears and the end
of the nose is also
cartilage).
Bone Formation, Growth, and Remodeling
Bone formation and growth
Ossification is the process of bone formation
Occurs on hyaline cartilage models or fibrous
membranes
Long bone growth involves two major phases
Two major phases of ossification in long bones
1.Osteoblasts (bone-forming cells) cover hyaline
cartilage model with bone matrix
2.In a fetus, the enclosed cartilage is digested away,
opening up a medullary cavity
Types of Bone Cells
Osteogenic cell or osteoprogenitor cells, are mitotically active stem
cells found in the membranous periosteum and endosteum.
Osteocytes—mature bone cells; monitor and maintain the bone matrix
Osteoblasts—bone-forming cells
Osteoclasts—giant bone-destroying cells
Break down bone matrix for remodeling and release of calcium in
response to parathyroid hormone
Bone remodeling is performed by both osteoblasts and osteoclasts
Bone Formation, Growth, and Remodeling
Appositional growth (growth from outside)
Bones grow in width
Osteoblasts in the periosteum add bone matrix to the
outside of the diaphysis
Osteoclasts in the endosteum remove bone from the
inner surface of the diaphysis
Interstitial growth (growth from within)
Bones expands
Lacunae bound chondrocytes divide and secrete new
matrix
Bone Formation, Growth, and Remodeling
Calcium ion regulation
Parathyroid hormone (PTH)
Released when calcium ion levels in blood are low
Activates osteoclasts (bone-destroying cells)
Osteoclasts break down bone and release calcium ions
into the blood
Hypercalcemia (high blood calcium levels) prompts
calcium storage to bones by osteoblasts
Bones of the Upper Limbs
Hand
Carpals—wrist bones
8 bones arranged in two
rows of 4 bones in each
hand
Metacarpals—palm bones
5 per hand
Phalanges—fingers and
thumb
14 phalanges in each hand
In each finger, there are 3
bones
In the thumb, there are only
2 bones