This presentation discuss anemia, etiology of anemia, different types of anemia, clinical signs, diagnosis and treatment of anemia.
Size: 1.93 MB
Language: en
Added: Aug 09, 2024
Slides: 30 pages
Slide Content
ANEMIA Published by Dr . Desh Deepak Assistant Professor, VMD, SVPUAT
ANEMIA Anemia is a condition in which number of red blood cells or their capacity is insufficient to meet physiological needs. Oxygen carrying capacity can be reduced due to following reasons Decreased volume of blood Decreased hemoglobin Decreased number of erythrocytes
Classification
Classifcation
Classification
Etiology Decreased production of Erythrocytes Increased destruction of erythrocytes Loss of erythrocytes or blood from body
Reduced production of Erythrocytes Malnutrition and Deficiency Castle factor deficiency Aplastic anemia CKD anemia CD
Increased destruction/loss of erythrocytes Hemolytic anemia (Drug, toxins, infections, protozoans, Immunological and mechanical trauma). Genetic causes like sickle cell, thalassemia, spherocytosis.
Loss of blood or erythrocytes Acute: Hypovolemia Chronic : GI bleedings (ulcer), P arasitic infestations
Clinical manifestations Weakness, E xircise intolerance Pale mucus membrane, I cterus and H aemoglobinuria
Diagnosis Diagnosis of anemia is mainly on the basis of mucous membrane and complete blood count. Anemia is categorized as mild, moderate and severe on the basis of packed cell volume. Normal or elevated or depressed level of MCV and MCHC are used in classification of anemia
Treatment
Treatment
Treatment
Treatment
Treatment
Disseminated I ntravascular Coagulation Dr. Desh Deepak Assistant Professor, VMD
Disseminated Intravascular Coagulation Synonyms: Consumption coagulopathy or defibrination syndrome Thrombo-haemmoragic syndrome caused by SIRS induced activation of coagulation cascade and characterised by depletion of clotting factors, paradoxical bleeding and (multiple organ dysfunction syndrome) MODS
Etiology Severe diseases and conditions that initiates SIRS viz septicemic diseases, toxemic diseases, metritis, mastitis, colitis, gastroenteritis, immune mediated diseases and severe traumatic injuries. Release of procoagulant material in blood in cancer and brain injuries.
Pathogenesis Two mechanisms responsible for DIC Excessive release of tissue factors/thromboplastin/factor III (severe trauma, surgeries, obstetric and sepsis) Widespread endothelial injuries
Pathogenesis
Pathogenesis
Clinical manifestations DIC produces two types of manifestations either bleeding or organ dysfunction. DIC is clinically presented in two major forms acute form which is fulminating DIC and chronic form with subclinical DIC without any bleeding symptoms Bleeding symptoms : Hematemesis, melena, pulmonary hemorrhages and excessive bleeding. Organ failure symptoms : Respiratory or renal insufficiency, hypotension and impaired cerebral blood flow