Antacids

Antacids

1. Antacids By: Isha Rani Assistant Professor MMCP, MMU- Mullana

2. Antacids “ The substance which neutralizes excess amount of acid in gastrointestinal tract is called as antacid” e.g : Sodium bicarbonate (NaHCO 3 ), Magnesium hydroxide Mg(OH) 2 Antacids

3. Ideal Properties of Antacids Should not be absorbable Fine particle size Should not cause constipation Should not cause systemic alkalosis Should not act as laxative Readily available Should not produce large volume of gas Non toxic

4. Types of Antacids Antacids are two types: Systemic (absorbable) Antacid : which are soluble, readily absorbable and producing alkalosis e.g. Sodium bicarbonate Non- Systemic (non-absorbable) Antacid: which are not absorbable and not produced systemic effect.

5. Non systemic antacids divided as Aluminium containing antacids : Aluminium phosphate, Aluminium hydroxide Calcium containing antacids: Calcium carbonate, tribasic calcium phosphate Magnesium containing antacids : Magnesium carbonate, magnesium hydroxide Combination antacids: Aluminium hydroxide gel and magnesium hydroxide