Antileprotic drugs

Pharmacology PPT

1. Antileprotic drugs

2. Which of the following antitubercular drugs is safe in hepatitis? (a) Isoniazid (b) Rifampicin (c) Pyrazinamide (d) Ethambutol

3. A diabetic patient develops cellulitis due to Staphylococcus aureus that was found to be methicillin resistant on the antibiotic sensitivity testing. All of the following antibiotics will be appropriate EXCEPT: (a) Vancomycin (b) Imipenem (c) Teicoplanin (d) Linezolid

4. Prolonged treatment with INH leads to deficiency of? (a) Pyridoxine (b) Thiamine (c) Pantothenic acid (d) Niacin

5. Commonest side effect of Dapsone is: (a) Hemolytic anemia (b) Thrombocytopenia (c) Cyanosis (d) Bone marrow depression

6. Ethambutol causes (a) Retrobulbar neuritis (b) Deafness (c) Red urine (d) Peripheral neuritis

7. In leprosy, the best bactericidal agent is: (a) Clofazimine (b) Dapsone (c) Rifampicin (d) Ethionamide

8. A patient suffering from AIDS is on zidovudine , lamivudine and indinavir therapy. He develops pulmonary tuberculosis for which treatment is started. Which of the following should be avoided in him? (a) INH (b) Ethambutol (c) Pyrazinamide (d) Rifampicin

9. The primary reason for the use of drug combination in the treatment of tuberculosis is to: (a) Ensure patient compliance with the drug regimen (b) Enhance activity against metabolically inactive mycobacteria (c) Delay or prevent the emergence of resistance (d) Provide prophylaxis against other bacterial infections

10. ATT causing orange coloured urine is (a) Rifampicin (DNB 2002, 2005) (b) Isoniazid (c) Streptomycin (d) Pyrazinamide

11. Which of the following antitubercular drug is not hepatotoxic (a) Isoniazid (b) Rifampicin (c) Ethionamide (d) Streptomycin

12. Corticosteroids are absolutely contraindicated in the following type of tuberculosis: (a) Miliary (b) Meningeal (c) Intestinal (d) Renal

13. A patient of multidrug resistant tuberculosis is on antitubercular drugs. After a few months he develops an inability to distinguish between red and green color. Most likely drug causing these symptoms is: (a) Rifampicin (b) Ethambutol (c) Cycloserine (d) Ethionamide

14. In Lepra reaction, the drug useful is: (a) Pencillins (b) Clofazimine (c) Dapsone (d) Rifampicin

15. MCQ