ARISHTA - ASAVA bhaishajya kalpana formuations.pptx

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1. ARISHTA and ASAVA formulations Batch – c Roll no. – 51 to 75

2. AGENDA Sandhana kalpana Preparation method Arishta Asava Market survey on Arishta Market survey on Asava

3. Sandhana Kalpana द्रवेषु चिरकालस्थं द्रव्यं यत्सन्धितं भवेत् । आसवारिष्टभेदैस्तु प्रोच्यते भेषजोचितम् || ( शा . सं . म. खं . 10/1) It is the process of fermentation where in the dravadravya along with other medicinal drugs is put in a closed inert vessel for a specified time period to carry out fermentation under favorable conditions. Asava & Arishta are the 2 major products of this process.

4. Preparation method Steps involved 1. Preparation of Infusion or decoction.
2. Addition of sweeteners, flavours and other additives.
3. Transfer into a fermenter.
4. Addition of fermenting agent.
5. Incubation at specified conditions, for a specified period.
6. Filtration.
7. Packing.

5. Arishta Self-generated alcoholic preparations, prepared from decoction of the raw drug. Asava Self-generated alcoholic preparations, prepared from juices of fresh plants or water soaked dry drugs. Difference

6. ARJUNA ARISHTA 1)Product name – ARJUNARISTA 2)Company name – DIVYA PHARMACY 3)Reference – SHARANGDHAR SAMHITA 4)Quantity – 450 ml 5)Price - ₹ 145/450ml 6)Ingredients – Each 100 ml prepared from-
• Arjuna ( St.Bk 39.06g)
• Draksa • Madhuka (FI. 7.81g)
• Water Q.S. - Prakshepa Dravya :-
• Guda (36.06g)
• Dhataki (FI. 7.81g) 7)Dosage – 12-24 ml or as directed by physician 8) Manufactured date- 1/2024 9)Expiry date- 12/2033

7. Indications of Arjunarishta : Arjunarishta (AA) is an ancient hydroalcoholic Ayurvedic formulation having the highest percentage of ARJUNA and used for the treatment of CVD. It nourishes and strengthens the heart muscle and promotes cardiac functioning by regulating blood pressure and cholesterol

8. KUTAJA ARISHTA • PRODUCT NAME- Kutajarishta •BRAND NAME- Baidyanath • REFERENCE –. Bhaishajya Ratnavali • QUANTITY – 200 ml •INGREDIENTS – Composition: Each 10 ml contains
1.Kutaj ( Holarheena antidysentrica ) - 3 g
2.Draksha ( Vitis vinifera ) – 1.5 g
3.Madhuka Pushpa – 300 mg
4.Gambhari ( Gmelina arborea )- 300 mg
5.Dhataki ( Woodfordia fruticosa ) – 600 mg PRICE- 75 Rs DOSAGE- 3-6 teaspoon full with equal quantity of water twice a day or directed by an physician . • MANUFACTURED DATE – March 2014 • EXPIRY DATE - March 2026 INDICATIONS – It is indicated for diarrhea , intestinal disorders and gastrointestinal disorders.

9. Research on KUTAJARISHTA : When the drug was given to patients with amoebiasis there was symptomatic relief. So it was necessary to find out whether the dugs have only action on the amoebae when The drugs were screened for anti-amoebic Action in vitro, it was found that they do not inhibit the growth of the amoeba in culture.
In animal experiment the drugs did not show any significant action on the caecal Pathology. These above findings do not co-relate with the observation of symptomatic relief in clinical amoebiasis . The notable finding of the action of the drugs was significantly lowering the level of 5-hydroxytryptamine (serotonin) in the Blood of treated animals. It has been reported earlier that lowering of peripheral level of 5-hydroxytryptamine in the host, reduces the disease producing capacity of E.histolytica ( Entiaz Ahmad et al., 1984). It is possible that the dug in question do not have any direct action on E- histolytica . But by lowering the peripheral serotonin level in Patients the drug may reduce the virulence of the amoeba and thereby providing symptomatic relief to the patients. For the study in this direction is needed to definitely establish the above possible action of the drug in am elioration of amoebiasis .

10. ASHOKARISHTA 1 .PRODUCT NAME – ASHOKARISHTA ( अशोकारिष्ट ) 2.COMPANY NAME – BAIDYANATH 3.REFERENCE – AYURVED SAR SANGRAHA 4.QUANTITY – 220 ML 5.PRICE – 70 RS. 6.INGREDIENTS – Ingredients for decoction: Ashok chhal (2.7 g). Gud (5.3g) Prakshep Dravya : Dhataki 425 mg. 7.DOSAGE – 3 TO 6 tsp. With equal quantity of water after meal . 8.MANUFACTURE DATE – 07 / 2021 9.EXPIRY DATE – 06 / 2031 10.INDICATION – Useful in relieving the problems caused during burning in the soles of hands and feet, backache, stomachache, headache, fatigue etc.

11. Reasearch on Ashokarisht –
1) Currently phytoestrogens are popular as hormone replacement therapy in postmenopausal women. Ashokarishta , a polyherbal ayurvedic drug has been used in India for a number of gynaecological problems including amenorrhoea , metrorrhaegia , menorrhaegia and dysfunctional uterine bleeding since thousands of year.
2) The present investigation showed that the alcohol content, water-soluble extractive value, alcohol-soluble extractive
value, total solid content, viscosity, surface tension, phytochemical screening etc. was found to be different in leading brands and in-house formulation of Ashokarishta . 3)ON From the present study, it is concluded that Ashokarishta are effective in the treatment of menopause-associated symptoms and can promote the quality of life of menopausal woman. Hence, these Ayurvedic formulations can be used effectively for the management of menopausal symptoms in place of HRT and other therapies.

12. DRAKSHARISHTA Product name : Draksharishta Company name : Shree Baidyanath Ayurveda Bhavan Reference : Sharangdhar Samhita Quantity – 450 ml Price –115rs Ingredients – Draksha 1.28 g , Guda 5.12 g , Dhataki Pushpa 204.8 mg , vidang , pippali , priyangu , Tvak ,Ela , Tejpatra , Nagakeshara , Marica – 25.6 mg , Asava base – Q.S Dosage : 3 to 6 teaspoonful with equal quantity of water , twice a day after meals Manufactured date : 2023 Expiry date : 2032 Indications - formulation is prescribed for digestive impairment, respiratory disorders .

13. Research on DRAKSHARISHTA : The objective of the present study was to evaluate the diuretic potential of Drakshasava -T and Drakshasava -M prepared by traditional and modern methods respectively and its marketed formulation in experimental rats using furosemide (10 mg/kg p.o. ) as a standard diuretic drug. Oral administration of Drakshasava -T, Drakshasava -M and its marketed formulation at the dose of 2.0 ml/kg over a period of 5 h showed a significant increase in urine volume as compared to control group. Both types of Drakshasava as Drakshasava - T and Drakshasava -M prepared by traditional and modern methods respectively and its marketed formulation showed significant increase in sodium, potassium and chloride level in urine sample as compared to control group. The maximum diuretic effect was produced by furosemide. Thus, both types of Drakshasava as Drakshasava -T and Drakshasava -M and its marketed formulation showed significant diuretic, natriuretic and kaliuretic effects.

14. MUSTAKARISHTA Product name – Mustakristha Brand name- B aidhyanath Ref- sarangdhar samhita Quantity- 450ml Price- rs150 Ingredients : Each 10 ml contains Musta – 3.03 g, Guda-4.48 g, Dhatak.Yavani , Sunthi , Marica , Lavanga , Methi , Citraka , Sveta Jiraka - 24.24 mg, Asav Base-Q.S. Dosage : 3 to6 tablespoon with equal quantity of water after meal Batch no: 195650001 Manufacture date :oct 2019 Exp date : sept 2029

15. KHADIRARISHTA 1) Product name – khadirarishta 2) Company or brand name – baidyanath 3)Reference – Sharangdhar Samhita madhyam khand 10 th chapter 4)Quantity – 220ml 5)Price – 105 ₹ 6)Ingredients : Khadirsar,Devdaru,Bawchi,Daruhaldi,Harre,Baheda , Prakshep Dravya : Dhaiphool,Kankol,Naghesar,Jaiphal , Lavang,Elaichi badi , Dalchini,Tejpatta , pippali,Arishta base 7)Dosage- as directed by physician 8) Manufactured date – 12/2022 9)Expiry date- 11/2032 Indications :
treating skin problems like skin allergies, itching, rashes, acne, atopic dermatitis, psoriasis, and urticaria

16. ASHWAGANDH- ARISHTA Product name- ASHWAGANDHARISHTAM Company – kottakkal Reference – Nagarjuna QUANTITY- 450ml PRICE - 150 rs INGREDIENTS – Makshika , Aswagandh,Musali , Haritaki,Manjista , Rajani , Darvi , Madhuka , Rasna , Vidari , Partha , Mustaka,Trivrit ,Ananta , Syama , Chandan , Raktachandana , Vacha Chitraka , Dhataki , Nagara , Maricha , Pippali ,Ela , Twak , Patra , Priyangu , Nagakesara . Dosage- 15 to 25 ml Manufacture date- 09/ 2022 Expiry date- 08/2032 Indication Ashwagandharishta is used in psychiatric disorders like epilepsy, depression, anxiety, schizophrenia, sluggishness, dullness, and other memory-related disorders

17. RESEARCH on ASHWAGANDHARISHTA: Ashwagandharishta , an Ayurvedic classical formulation, is the remedy for Apasmara (epilepsy), Murchha (syncope), Unmada (psychosis), etc. Recent studies in animal models have shown that n-3 PUFAs can raise the threshold of epileptic seizures. The indigenous medicinal plant, called Atasi ( Linum usitatissimum Linn.) in Ayurveda, or flax seed, is the best plant source of omega-3 fatty acids. The present study is de- signed to investigate whether Ashwagandharishta and Atasi taila (flax seed oil) protect against maximal elec - troshock (MES) seizures in albino rats. Further, a possible protective role of flax seed oil as an adjuvant to Ashwagandharishta in its anticonvulsant activity has also been evaluated in the study. MES seizures were induced for rats and seizure severity was assessed by the dura - tion of hind limb extensor phase. Phenytoin was used as the standard antiepileptic drug for comparison. Both flax seed oil and Ashwagandharishta significantly decreased convulsion phase. Pre-treatment with flax seed oil exhibited significant anticonvulsant activity by decreasing the duration of tonic extensor phase.

18. DASHMULARISHTA Product – Dashamularishta Brand name – Sandu pharmaceuticals Reference – Bhaishajya Ratnavali Quantity – 200 ml Price – 140.00 rs Ingredients – Bilva , kasmarya,patla,agnimantha , shovyak ,, Gambhari , Shalaparni , prishniparni , brihati , kantakari , gokshura , chitrak , pushkar , lodhra , guduchi , amlaki , durlabha , etc.
Self generated alcohol not more than 11%v/v Dosage – 10-20 ml twice a day Indication – vatavikara , debility, postnatal care, cough, IBS Batch no . – GA-108 Mfg date – 10/2023 Exp date – 09/2033

19. Each 10 ml DASHMULARISHTA contains: Bilava (Aegle Marmelos Rt.) 0.09 mg Shyonak ( Oroxylum indicum Rt.) 0.09 mg Gambhari ( Gmelina arborea Rt.) 0.09 mg Patala ( Stereospemum suaveolens Rt.) 0.09 mg Arani Chhal ( Clerodendrum multiflorum Rt ) 0.09 mg Shalparni ( Desmodium gangeticum Rt.) 0.09 mg Prishparni ( Uraria picta Rt.) 0.09 mg Brihati ( Solanum indicum Rt.) 0.09 mg Kantakari ( Solanum virginianum Rt.) 0.09 mg Gokshura ( Tribulus terrestris Rt.) 0.09 Amalaki ( Emblica officinalis Fr.) 0.30 mg Duralabha ( Fagonia cretica Pl.) 0.22 mg Khadir (Acacia catechu Ht. Wd.) 0.15 mg Vijaysar ( Pterocarpus marsupium Ht. Wd.) 0.15 mg Haritiki (Terminalia chebula Fr. P) 0.15 mg Kushta ( Anacyclus pyrethrum Rt.) 0.03 mg Manjishtha ( Rubia cordifolia St.) 0.03 mg Devdaru ( Cedrus deodara Ht. Wd..) 0.03 mg Vidanga ( Embelia ribes Fr.)- 0.03 mg Yashtimadhu ( Glycyrrhiza glabra Rt. ) 0.03 mg

20. Dashamoola , in the form of arishta and kwath , is a commonly used classical Ayurvedic multi-ingredient formulation for management of pain, arthritis and inflammatory disorders. Objective :
To study analgesic and anti-inflammatory of Dashamoola and its combination with aspirin. Materials and Methods : Wistar albino rats (180-200 g) and Swiss albino mice (20-25 g) of either sex were divided randomly into five groups: Distilled water, aspirin (500mg/kg in rats; 722.2 mg/kg in mice), Dashamoolarishta (1.8 mL/kg in rats; 2.5 mL/kg in mice) and Dashamoolarishta with aspirin. Anti-inflammatory activity was measured by change in paw volume in carrageenan-induced inflammation, Analgesic effect was evaluated by counting number of writhes in writhing model. Statistical analysis was done using one way ANOVA (post hoc Tukey’s test) and P < 0.05 was considered significant .

21. Results : Dashamoolarishta and its combination with aspirin showed significantly (P < 0.01) less number of writhes. It showed significant (P < 0.001) anti-inflammatory activity by paw edema reduction in rats, Dashamoola kwath alone and in combination with aspirin inhibited maximum platelet aggregation and percent inhibition of platelets as compared to vehicle (P < 0.001). Conclusion : Dashamoola formulation alone and its combination with aspirin showed comparable anti-inflammatory, analgesic effects to aspirin.

22. VIDANGARISHTA 1)Product name - vidangarishta 2)Company name- sandu 3)Reference- bhaisajya ratnawali 4)Quantity -450 ml 5)Price -205 rs 6)Ingredients – Amlaki , Pippali , Fruit Vidanga , Pippalamool , Dhatri Rasna , Kutaja Prakshepa Dravyas : , Dhataki , Twak , Kanchanara , Lodhra Shunti , Patra , Ela , Priyangu , Marich Sandhana Dravya - dhataki , 7)Dosage 10-20ml twice a day..as referred by physician 8)Expiry date- December 2025

23. Indications of Vidangarishta . Vidangarishta are mainly useful in Krumivyadhi (worm infection) and other Vyadhi like Urustambha , Vatvyadhi , Ashmari (kidney stone), Prameha (diabetes mellitus), Vidradhi (abscess), Bhagandara (fistula). So we preparing Vidangarishta by traditional method and pharmaceutico -analytical study is do ne.

24. Potential use of vidangaristha for parasitic infections :
In a study conducted in 2010, it was found that vidangarishta might have an effect on the parasitic worms that infest the stomach. This effect is achieved by worm paralysing and worm destroying activity that it might possess. Most of the diseases caused by these worms that infest the stomach cause hardships to the host by causing pain and may even lead to stunting of growth. Potential use of vidangarishta for anaemia : Anaemia can be caused due to infestation of worms in the stomach. The parasitic worms hog all the nutrients and might cause anaemia . Thus, as vidangarishta might be helpful against worm infestations, may also help with anaemia caused due to it.2,3 However, more studies are required to prove such effects of vidangarishta . Kindly consult an Ayurvedic physician and do not self-medicate.

25. . LOHASAVA 1 . PRODUCT NAME- LOHASAVA. • BRAND NAME - BAIDYANATH • REFERENCE –. SHARANGDHAR SAMHITA • QUANTITY – 450 ml • INGREDIENTS –. Composition: Each 10 ml prepared from Fine Powders of: Amalaki , Yavanika Sunthi , Marica , 10ml Contains 1.081g, Asav Base-Q.S. Dhataki-337.5mg, Guda-14 Vidanga , Mustaka, Citra Pippall , Haritaki , Bibhitaki , Loha Churna Shodhit ,
COMPOSITION: Each 1.418mg, Madhu - 67.5mg each

26. • PRICE- ₹ 137 – 450ml USP- ₹ 0.30 / ml • DOSAGE- 3 to 6 teaspoonful with equal quantity of water twice daily after meal or as advised by physician • MANUFACTURED DATE –. November/2023. • EXPIRY DATE – October/2033 • INDICATIONS – Useful in anemia, hepatomegaly, splenomegaly, also useful in loss of appetite , swelling on hands and feet etc.

27. LOHASAVA-2 • BRAND NAME- PATANJALI Ayurved • QUANTITY - 450 ml • INGREDIENTS –. Composition: Each 100 ml prepared from Fine Powders of: Sunthi Rz . 0.78g, Marica Fr. 0.78g, Haritaki P. 0.78g, Bibhitaka P. 0.78g, Amalaki P. 0.78g, Yavani Ft 0.78g, Vidang Fr. 0.78g. Musta Rz.0.78 Eranda Rt. 0.78g, Dhataki Fl.0.78 Madhu 12.5g, Guda 19.53g, Water Q.S. 173 • PRIce - ₹ 100 – 450ml USP- ₹ 0.22 / ml DOSAGE- 12-24 ml with equal amount of water before meal.

28. Clinical trial data on Lohasava is indicative of its statistically significant efficacy in Shwasa . Lohasava increases the Hb % and red cell indices which facilitates more oxygen supply to alveolar cells and may reduces Vata . It has an Rasadhatu vridhhi like activity and helps In improving Agni by its Katu Rasa5,6,9 Laghu Guna , Ushna veerya , property. Possibly due to Agnivridhhi , proper Dhatu Paka occurs. The ingredients of Lohasava may work synergistically to increase the oja dhatu which ultimately relieves shwasa . Lohasava controls the symptom of Hritspandan in better way. improves the cardiac function and reduce the cardiac volume. Lohasava regulates the proper formation of Rasa dhatu . There was a statistically significant improvement in shrama (Fatigue) in Lohasava group. Fatigue in iron deficiency anaemia is due to the hypodynamic circulation which ultimately results Rasa kshya . Lohasava18 Ingredients facilitate proper formation and distribution of Rasadhatu . On an overall Lohasava ingredients permeate the micro channels in a better way. Lohasava on its effect on shrama lead to a remarkable feeling of well-being and patients regained their confidence to resume their usual activities.

29. KUMARI ASAVA 1)Product name – kumari asav 2)Company name – Sandu 3)Reference – Sharangdhar Samhita madhyam khand 10 th chapter 4)Quantity – 200 ml 5)Price – 105 ₹ 6)Ingredients- Kumari ras 66.2% , Guda 25.85%, Makshika12.92% , Dhataki 2%, 7)Dosage- as directed by physician 8) Manufactured date –12/2021 9)Expiry date- 11/2031 Indications : beneficial in managing various conditions like digestive impairment, duodenal ulcers, urinary disorders, bleeding disorders, epilepsy, worm infestation, loss of memory, weakness, diseases of the abdomen, and tastelessness.

30. Research on kumariasava : The anti-cancer properties of the extracts of Aloe vera against the Hela cells of human was evaluated in tissue culture, in this study. The toxicity effects of different concentrations 16, 17, 18, 19, 20 and 21 mg/ml of extract of Aloe vera on the Hela cells of human, were evaluated using Trypan blue and MTT methods, on 24, 48 and 72 hours after exposure to a medium containing 1% serum and extracts. The final results show that 20 mg/ml concentration of Aloe vera extract was effective in inhibiting the proliferation of Hela cells of human. The herb Aloe vera L. proves to be a novel component for manging the Polycystic Ovarian Syndrome (PCOS) phenotype. Aloe vera gel formulation exerts a protective effect in against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity. The phytochemicals in the Non-polar fraction of Aloe vera L. have proven to manage PCOS by modifying steroidogenic targets. The huge possibilities in the area are further substantiated by studies that prove the angiogenesis effect of Aloe vera L. and its therapuetic effect like that of follicle-stimulating hormone in ovaries. Further the Oral administration of Aloe vera L. reduced circulating blood glucose concentrations to a normal level, significantly decreased plasma insulin, and lowered triglyceride levels in the liver and plasma in mice models.

31. KUMARI ASAVA no.1 1) Product name – Kumari asav no. 1 2)Company name – Dhootpapeshwar 3)Reference – Sharangdhar samhita 4)Quantity – 450 ml 5)Price – 210 ₹ 6)Ingredients- Each 10 ml contains Kumari 5925 mg, Haritaki 579 mg , Madhu 1481 mg , Dhataki 370mg , loha bhasma , tamra bhasma -12 mg 7)Dosage – 2-4 teaspoonful twice a day / as directed by physician 8) Manufactured date – 04/2021 9)Expiry date- 03/2031 10) Indications - digestive impairment, duodenal ulcers, urinary disorders, bleeding disorders, epilepsy, worm infestation, loss of memory, weakness, diseases of the abdomen, and tastelessness.

32. DRAKSHASAVA Brand name – Baidyanath Asli Ayurved Reference - Sar Sangraha Quantity - 220 ml Ingredients – Draksha , shakku , dhataki , kankol , lavang , jaiphal , Kalimirch , Dalchini , Elaichi , Tejapatra , nagkeshar , pippalimul , chavya , chitrak , Preservatives. Price – 125rs Dosage – 3 to 6 tsp with equal quantity of water after meal daily Manufactured date – 11/2022 Expiry date – 10/2032 indications - Helps to relieves problems related to anemia Jaundice, debility, Cough, Piles. Helps to relieve the problems related to throat, eye and skin. Research - Drakshasava is a polyherbal hydroalcoholic preparation and is used to improve digestic digestion, as blood purifier, in the treatment of anemia and adviced a choice of remedy in respiratory problems. The chief ingredient is draksha , dried vitis vinifera .

33. PIPPALYASAVA-1 Product name : pippali asav Brand name : sandu Refrence : Sharangdhara samhita Quantity : 200 ml Price : 120/- Ingredients : pippali,marich , chavya Haridra , chitrak , vigandha , Musta , puga , patha , amalaki , Elavaluka , ushir , shvet chandan , pokhar mul , lavanga , takgara , jatamansi , tvak ,Ela , tejpatra , priyangu , nageshwar each 0.06462% , guda 38.7838%, Dhatki -1.2928% , draksha – 61.623% . Dosage : 10-20 ml twice a day or as directed by physician. Manufactured date : 07 / 2021 Expiry date : 06/ 2031. Indications : significant in dealing with gastrointestinal aberrations like bowel diseases, indigestion, intestinal gas, ulcers, abdominal distension, loss of appetite, anorexia

34. PIPPALYASAVA-2 1. product name- pippali asava 2. Brand name – Baidyanath 3. Reference – Sharangdhara samhita 4. Quantity -450ml 5. Ingredients – Each 10 ml. Contains extract derived from – Pippali , Maricha , lavanga , Tvak , Tejapatra , Ela, chavya , Haridra , Citraka mula , Musta , Vidanga , Puga , Lodhra Chaal , Patha , Amalaki , Kumari , Usira , Candana , Kustha , Tagara , Jatamamsi , Priyangu , Nagakesara each 10 mg., Draksa 1.15 gm. Dhataki puspa 140 mg Asava Base –Q.S. 6. Price- 205 rs . 7. Dosage – 3 to 6 teaspoons with equal water twice after meals 8. Manufacture date- 02/2020 9. Expiry date – 01/2030 10. Indications – anemia,loss of appetite,liver complaint, digestive complains,leucorrhoea and high body temperature.

35. PRODUCT NAME- BHRINGASAVA BRAND NAME- SANDU REFERENCE –. Bhaishajya Ratnavali INGREDIENTS –. Composition: Each 5 ml prepared from Fine Powders of: Bhringaraj (830mg), Haritaki (155.6mg), Pippali (Piper longum ) 0.78g Jaiphal 0.78mg Lavang 0.78mg Twak 0.78mg Elaichi 38.7mg Dhataki 50mg gud PRICE- . 162 rupees – 450ml USP- 0.36 Rupees/ ml DOSAGE- . 20ml twice a day or as directed by physician MANUFACTURED DATE – March /2018 INDICATIONS – Useful in hair , premature greying of hair , general debility BRINGARAJ ASAVA- 1

36. BRINGARAJ ASAVA 2 PRODUCT NAME- Bhringasava BRAND NAME- VAIDYARATNAM REFERENCE –. GADANIGRAHAM PRICE – 200/- USP- 0.44 Rupees/ ml DOSAGE- . 20ml twice a day or as directed by physician MANUFACTURED DATE – 2023 EXPIRY DATE – 2025 INDICATIONS – Useful in hair , premature greying of hair

37. Research on BHRINGARAJASAVA : The clinical study was conducted at the Out Patient Department of State TB Training and Demonstration Centre, S.R. Nagar, Hyderabad, Andhra Pradesh, India, during June 2003 to December 2004. A group of 60 patients of PTB were included in the study and were divided into two equal groups. Both the groups were on the Directly Observed Treatment Short – course chemotherapy (DOTS) regime. The test group was given DOTS + Bhringarajasava (30 ml thrice a day) and the control group was only on DOTS. The study was to evaluate whether the addition of Bhringarajasava as Naimittika Rasayana (complementary drug) is beneficial in providing faster and better relief or not. Both subjective and objective parameters were considered for the assessment of results. Among the specific symptomatology, Amsaparsabitapah (pain in costal and scapular region), Kasa (cough), Jwara (pyrexia), Swasa ( dyspnoea ) and Bhaktadwesha (anorexia) were the symptoms manifested by all the patients. Results of the present study indicate that better, safer, and faster relief provided by the addition of Bhringarajasava to DOTS. This is an effort to utilize drugs from the vast Ayurvedic pharmacopoeia as safe adjuvant to DOTS regime so that toxicity and associated side effects of the DOTS can be ameliorated. This process of using therapies from two disparate systems of medicine could potentially lead to further enhancements in the field of complementary medicine and create a symbiosis between the different systems, which may lead to Rasayana DOTS (R-DOTS) in future.

38. Ingredients of bhringrajasava : Composition: Each 10 ml prepared from
Juice of eclipta alba. 7.26ml
Powder of:
Terminalia chebula . 0.218g
Piper longum . 0.0545g Myristica fragrans . 0.0545g Syzygium aromaticum . 0.0545g Cinnamomum zeytanicum . 0.0545g Elettaria cardamomu 0.0545g Mesua ferreg . 0.0545g
Base and othersa:Jaggery 5.45g

39. PATRANGASAVA *1)Product name * : patrangasava *2)Company name * : Divya pharmacy **3)Reference * - Bhaishajya Ratnavali *4)Quantity * -450 ml *5)Price * : 175rs *6)Ingredients * : Prakshepa Dravya : Patangkasth ( HtWd . 0.20 g). Khair ( StBk . 0.20 g), Vasak (Rt. 0.20 g), Semal phool (Pl. 0.20 g), Shuddha bhilava (St. 0.20 g), Safed sariva Fl. 0.20 g, Aam Sd. 0.20 g, Daru S. 0.20 g. Dhaiphool , Water Q.S. *7)Dosage * :12-24 ml with equal amount of water after meal or as directed by Physician *8) mfg date * : 12/2023 *9)Expiry date * :11/2033
. 10) Indications : management of gynecological conditions such as heavy menstrual bleeding, leucorrhea, menorrhagia and fever etc.

40. GOKSHURADI KADHA 1.Product name : Gokshuradi kadha 2 .Company/Brand name : Baidyanatha 3. Indications- Gokshuradi Kadha is an ayurvedic treatment for kidney stones and other urinary problems. It has diuretic and antiurolithiatic properties. It dissolves and excretes urinary stones, relieving pain and making urination easier. 4.Quantity : 200ml 5.price : 105rs 6.ingredients : gokshura1g, sothaghni400mg, varuna chhal400mg, dhataki10mg, kadha base, permitted preservatives 7. Dosage : 2-3 table spoon with equal quantity of water after meal or as directed by physician 8. Manufacturing date : 8/22 9.Expiry date : 7/25

41. Reasearch on Gokshuradi kadha : The herb’s wide-ranging curative effects led to its discovery. The diuretic and nephroprotective effects of Gokshura have been the subject of several studies. The corresponding studies are included down below. The Gokshura extract made the rats urinate more often, according to the Journal of Ethnopharmacology . An announcement was made to the spectators. Urine and salt production were both boosted throughout this routine. This change boosted its ability to focus. The lowering of creatinine levels in the study is indicative of the medicine’s nephroprotective effects. Renal function and urine output were reported to be enhanced by Gokshura extract in another study published in the Indian Journal of Experimental Biology. As the investigation revealed. Rats with simulated renal failure were employed in this investigation. Rats were developed for this trait on purpose. Clinical research published in the Journal of Study in Ayurveda looked at the effectiveness of Gokshura in treating urine disease .