Arvindasava

1. ARVINDASAVA FORMULATION SEMINAR BY DR. MITHILA V. A. GUIDED BY DR. AZIZ A. A. & DR. VEENA S. T.

2. CONTENTS OBJECTIVES REFERENCE INGREDIENTS HYPOTHETICAL ASSESSMENT OF PHARMACODYANAMICS OF INGREDIENTS APPLIED ASPECTS QUALITY CONTROL RECENT RESEARCH WORKS DISCUSSION SUMMARY

3. OBJECTIVES

4. P reparation of Arvindasava according to classical methods. Discussion on the practical applicability of Arvindasava in day-to-day pediatric practice.

5. REFERENCE

6. Reference text : B haisajya Ratnaavali Adhikaar : Baala Roga Adhikaar Sloka : 161 – 165 (1) Arvinda ushiram cha kashmari neelam utpalam . Manjishta ela balaa mansi ambudam sarivaam shivaam . Bibhitaka vacha dhatri shati shyama sa neelinim . Patola parpatam partham madhuukam madhukam muram . Pala maanen sangruhya drakshayam pala vimshatim . Dhatakim shodash palaam jala drone dvaye kshipeta . Sharkarayaa tulam tatra tulaardha makshikasya cha. Maansamstapayetbhandemritikaparinirmitte . Baalanaam sarvarogagnau bala pushti agni vardhana . Arvindasavah proktah aayushyo grahadosh hrut .

7. NAMING OF THE KALPA Based on the name of the first ingredient

8. PRAMAANAS Druvaya-maan Jala = 25 litres ( dvaya drona ) Pautava-maan Guda = 4670 grams ( tula ) Madhu = 2335 grams ( tula-ardham ) Draksha = 940 grams ( vimshati pala ) Dhataki pushpa = 750 grams ( shodash pala ) Prakshepa dravyas = each 46 grams ( 1 pala ) Kaal-maan 1 maasam

9. SAMBHARA Preparation of the mrutikka patra An earthen vessel of approx 40-50 litre capacity is selected it is filled with water till its rim and this water is kept overnight in it and discarded in the next morning. The vessel is cleaned by rubbing it with husk and thoroughly cleansed 2-3 times with water. It is placed in a clean room devoid of wind. It is placed amidst the heap of husk. After adding all the ingredients it is closed with an earthen sharava and sealed with kapada-mrutika . (1)

10. METHOD OF PREPARATION 25 Litres of jala is added to the earthen vessel. Guda and madhu is added to water. Draksha is pounded and added. Sun dried Dhataki pushpa is added without pounding it. All the prakshep dravyas are made into yavakutta churna form mixed priorly and then added. All ingredients are mixed thoroughly. The earthen vessel is sealed and left undisturbed for a period of 1 month. The liquid thus obtained is strained and again placed in the earthen vessel for a period of 10 days during which the thicker layer and sediments settle down. The upper layers are collected and packed in glass bottles with appropriate labeling. (1)

11. INGREDIENTS

12. INGREDIENT CLASSIFICATION Sthavara dravyas all 23 prakshepas Guda Draksha Dhataki pushpa Janghama dravyas Madhuvarg – madhu Audbhida dravyas Nil Jala varga Jala

13. DRAVYA LATIN NAME FAMILY UPYUKT-ANGA RAS VIPAAK VIRYA GUNA DOSHAGNATA KARMA ARVINDA Nelumbo nucifera Nymphaceae rakta / shveta pushpa m m s La. Sni . Pi. Pi. Ka. mutravirajniya USHIRA Vettivera zizanoides Graminaceae mula t k s La. Ru . Pi. Ka. Daha-prashman KAASHMARI Gmelia arborea Verbenaceae phala m m s Sni . Gu . Pi. Va. Daha-prashmana virechanopaga NEELOTPALA Nelumbo stellata Nymphaceae Nila pushpa Ks m s La. Sni . Pi. Pi. Ka. Daha-prashmana

14. DRAVYA LATIN NAME FAMILY UPYUKT-ANGA RAS VIPAK VIRYA GUNA DOSHAGNATA KARMA MANJISTHA Rubia cordifolia Rubiaceae mula m k u Gu . Ru . Tri. Ra. jvarhara ELA Ellataria cardamomum Zinziberaceae phala k m s La. Sni . Sug . Suk . Tri. ? Eladi Angmard-prashman BALA Sida cordifolia Malvaceae mula m m s La. Sni . Pi. Tri. Balya bruhaniya praja-stapaniya MANSI Nardostachys jatamansi Valerianaceae mula Ks m s La. Sni . Tri. Sangya-stapana bhutagna

15. DRAVYA LATIN NAME FAMILY UPYUKT-ANGA RAS VIPAK VIRYA GUNA DOSHAGNATA KARMA AMBUDAM Cyperus rotundus cyperaceae Kanda t k s La. Ru . Pi. Ka . Triptighna Trishna-nigrahaniya SAARIVAA Hemidesmus indicus asclepaedaceae Mula m m s Gu . Sni . Tri. Daha-prashman stanya-shodhan jwarahar SHIVAAM Terminalia chebula combrataceae Phala p m u La. Ru . Tri. Jwaraghna kushtaghna BIBHITAKA Terminalia belerica combrataceae Phala Ks m u Gu . Ru . Pi. Ka . Jwarhar virechan-opaga

16. DRAVYA LATIN NAME FAMILY UPYUKT-ANGA RAS VIPAK VIRYA GUNA DOSHAGNATA KARMA VACHA Acorus calamus Araceae Kanda k k u La. Ru . Ti. Ka . Va. Medhya sangya-stapan virechaniya DHATRI Emblica officinalis Euphorbiaceae Phala p m s La. Ru . Tri. Virechan-opaga SHATI Acacia catechu Mimosae leguminosae Tvak / Kadhirsara t k s La. Ru . Pi. Ka . Kushtaghna ? Salasaradi gana SHYAMA Operculina turpenthum Convolulaceae Mula tvaka k k u La. Ru . Pi. Ka . Bhedhaniya

17. DRAVYA LATIN NAME FAMILY UPYUKT-ANGA RAS VIPAK VIRYA GUNA DOSHAGNATA KARMA NEELIKA Indigofera tinctora Papilonaceae leguminosae Mula k k u La. Ru . Va. Ka . virechaniya PATOL Tricosanthes dicora Cucurbitaceae Panchang of vanya variety t m u La. Sni . Tri. Trishna-nigraha triptigna PARPATA Fumaria vaillantii Fumariaceae Panchang t k s La. Pi. Ka . Trishna-nigraha PARTH Terminalia arjuna Combrataceae Twak Ks k s La. Ru . Pi. Ka . ? Udarda prashmana Salasaradi nyagrodadhi

18. DRAVYA LATIN NAME FAMILY UPYUKT-ANGA RAS VIPAK VIRYA GUNA DOSHAGNATA KARMA MADHUUKAM Madhuca indica Sapotaceae Tvak Beej m m s Gu . Pi. Va. Shonita-stapana MADHUKAM Glycyrrhiza glabra Papilonaceae Leguminosae Mula m m s Gu . Sni . Pi. Va. Shonita-stapana MURAM Marsdenia tenacissima Asclepedaceae Mula t k u Gu . Ru . Tri. Pitta- saarak rakta-shodhak DRAKSHA Vitis vinifera Vitaceae Phala m m s Sni . Mri . Pi. Va. Virechan-opaga jwarhar

19. DRAVYA LATIN NAME FAMILY UPYUKTA-ANGA RAS VIPAAK VIRYA GUNA DOSHAGNATA KARMA GUDA su . Su. 45/160 - - m m a Sni . Va. Pi. Balya vrushya medakar MADHU - - nectar Ks m s Gu . Ru . Pi. Ka. Ra. Chedan DHAKTAKI Woodfordia fructicosa lythraceae pushpa Ks k s La. Ru . Pi. Ka. Mutra-virajniya

20. GRANTHOKTA GUNA DHARMA

21. Baalaanaam Sarva-rogaghno Bala-pushti Agni- vardhanah / Arvindaasava Prokta Aayusho Grahadosh-hrut // According to the text – Arvindasava is useful in - all the diseases of the children -it helps to improve strength, nutrition and digestive fire. -it bestows longevity -it helps to combat graha doshas (1)

22. RECENT RESEARCH WORKS

23. Acc to the research carried out by Sekar and Marriappam Indian Journal of traditional knowledge Arvindasava was found to be effective on Fever Cough Digestive disorders Constipation As an appetizer and growth promoter

24. HYPOTHETICAL ASSESSMENT OF PHARMACODYANAMICS OF INGREDIENTS

25. FEVER Aravinda – Jwaragna Nilotpala – Dahagna Kashmari - Vata Jwaragna Musta - Amashayagata Dosha Pachana Patola – Expels Niramadosha

26. KASA Manjishta – Kaphaja Kasagna Kashmari - Kaphasyanata Bala - Kshayaja Kas Sariva – Kshataja Kas Bibitaki – Bronchial Oedema Yastimadhu - Expectorant

27. AJIRNA Usira – Deepana Pachana Jatamamsi – Yakrututejaka ( Tikta Rasa) Musta - Deepana Pachana Shresta Vacha – Agnideepana Pachana

28. BADDHA KOSHTA Kashmari – Anulomaka Trivrut – Sukha Virechaka Patola - Anulomaka

29. ARUCHI Ela – Sugandi Sariva – Ruchikara

30. MUTRAKRICHRA Kamala – Mutra Krichrahara Mutra Virajaniya Ushira - Bastigata Pitta Reduced Kashmari – Basthi Shota Hara Ela – Mutrajanana ( Sheeta Virya ) Bala – Mutrakrichra Hara ( Vatanulomana ) Musta - Mutravruddi ( Jaliya ) Draksha – Mutradaha Hara

31. KARSHYA Kamala – Balya-Kshayagna Kashmari – Katupaushtika-Brumhaniya Bala – Mamsa Meda Majja Vardaka Amalaki – Rasayana Madhuka - Balya Draksha - Kshaya

32. GRAHA Ushira – Murcha Hara- Jeevaniya mastishkya Manjishta – Eliminates Irritability Jatamamsi – Manasa dosha hara , Rakshogna Vacha - Best for bala graha Amalaki - Gyanendriya Vardhaka Yashtimadhu - Medhya

33. APPLIED ASPECTS

34. DOSAGE 8 – 10 drops (1) Adult dosage : 1-2 tola Pediatric dose : 3-6 masha (2)

35. TIME OF ADMINISTRATION A dhobhakta

36. EXPIRY DATE Saviryata avadhi Puraanah syu gunair yukta asava dhatvo rasaah .

37. QUALITY CONTROL

38. TESTS Tests to ascertain onset of fermentation Floating Efferevesence Hissing Candle test : extinguishes Lime water test: milky

39. Tests to ascertain completion of fermentation Sunken prakshepaka dravyas Absence of effervescence No sound Candle test: burning Lime water test: no color change.

40. PHYSICAL PROPERTIES Varna : R aktabha Roop : Taral drava Ras : Madhura-tikshana Gandha : Madhya- gandhi (1)

41. DISCUSSION

42. Which guda ? Supuraana guda Adhika guna pathya tama Su su 45/ 160 Which honey? Makshika variety resembling colour of tila taila is best as compared to bhramara , kshaudra and paitikka cha su 27/243-246

43. SUMMARY

44. REFERENCES (1) Sen GD . edited by Mishra SN . Bhaisajya Ratnavali . Edn.1 st . Varanasi: Chaukambha Surbhartiya Prakashan ; 2007 ; pp:1093 ; chap:71 ; verse:161-165. (2) Ghune GG . Ayurvediya Aushadi Guna -dharma Shashtra . Edn 1 st . Pune : Vaidya Granth Bhandaar ; 2008 ; pp:618 ; part:5 ; chap:3.