Assymetric synthesis or stereoselective synthesis

837 views 18 slides Jun 20, 2020
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About This Presentation

This slide discuss about Assymetric synthesis of optically active product from optically inactive substrate.


Slide Content

Assymetric synthesis or stereoselective synthesis Lecture by S.Mathivanan . M.Pharm Asst professor Dept of Pharmacy

Assymetric synthesis Assymetric synthesis is synthesis of optically active product from optically inactive substrate with or without use of enantiomers . Types : Absolute assymetric synthesis Partial assymetric synthesis

What is the need for assymetric synthesis...???

Mechanism of Assymetric synthesis

Absolute assymetric synthesis Synthesis of optically active product from optically inactive substrate without using enantiomer . Br 2

Using circularly polarised light

Phase transfer catalysis

Partial assymetric synthesis Synthesis of optically active product from optically inactive substrate by using enantiomer

Use of Chiral auxillary (Second generation method)

Use of Chiral reagent (Third generation method)

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