INTRODUCTION: Asthma is a lower respiratory tract disease;it is an pulmonary obstructive disease.It is also called as “REACTIVE AIRWAY DISEASE
D E F I N I T I ON: Asthma is a common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction and bronchospasm . Common symptoms include wheezing , coughing , chest tightness, and shortness of breath
INCIDENCE: It can occur in any age and in any sex 26 million are diagnosed with asthma every year 10.6 million people are affected Womens are increased risk of death compare to men In India 4000-6000 are dying every year with asthma
Early and Late Phases of Responses of Asthma Fig. 28 - 1
CLINICAL MANIFESTATIONS: Wheezing Cough Chest tightness Dyspone Hypoxia Nasal flaring Sputum is thick and tenacious Decreased or absence of breath sounds called “SILENT CHEST”
SYMPTOMS:
ASSESSMENT AND DIAGNOSTIC STUDIES: History collection Physical examination Pulse oximetry Pulmonary function test Arterial blood gas Complete blood count Chest x-ray
Treatment While asthma cannot be cured, it can be controlled: Medications Long term Quick relief Bronchial thermoplasty Learning to recognize one’s own triggers and taking steps to avoid them.
Treatment Medication Long term Inhaled corticosteroid Leukotriene modifiers Long-acting beta agonists Combination inhalers
Treatment Quick relief (rescue) medications Short-acting beta agonists Ipratropium Oral and intravenous corticosteroids Bronchial thermoplasty Recognizing, tracking, and avoiding triggers
MANAGEMENT: Medications: Bronchodilators: -long acting beta adrenagic blockers: eg:salmeterol,formeterol,theophylline Anti-inflammatory drugs: -corticosteriods: eg :fl un i s o l i d e s, b ecla m e t ha s o n e ,c ro m o l yn -Mast cell stabilizers: eg:montelukast,zileuton DRY POWDER INHALERS
CORTICOSTEROIDS ARE MOST EFFECTIVE
DELIVERY METHODS: Medications are typically provided as metered-dose inhalers (MDIs) in combination with an asthma spacer or as a dry powder inhaler . The spacer is a plastic cylinder that mixes the medication with air, making it easier to receive a full dose of the drug. A nebulizer may also be used.
ADVERSE EFFECTS: Long-term use of inhaled corticosteroids at conventional doses carries a minor risk of adverse effects.Risks include the development of cataracts and a mild regression in stature.
OTHER METHODS: When asthma is unresponsive to usual medications, other options are available for both emergency management and prevention of flareups. For emergency management other options include: Oxygen to alleviate hypoxia if saturations fall below 92%. Oral corticosteroid are recommended with five days of prednisone being the same 2 days of dexamethasone .
Magnesium sulfate intravenous treatment has been shown to provide a bronchodilating effect when used in addition to other treatment in severe acute asthma attacks. Heliox , a mixture of helium and oxygen, may also be considered in severe unresponsive cases
COMORBIDITES:
NURSING MANAGEMENT: Check vitalsigns at regular intervals. Monitor allergic symptoms. Administer medication, note action of medications. Avoid exposure to pollution environment. Deep breathing exercises. Health education.