OVERVIEW WHAT IS ATRIAL FIBRILLATION? WHY IT IS IMPORTANT? PATHOGENESIS TYPES OF ATRIAL FIBRILLATION DIAGNOSIS WORKUP MANAGEMENT
ATRIAL FIBRILLATION First described by Sir William Harvey in 17th century observed chaotic motion of atria in open chest animal ECG findings described in 1909 by Sir Thomas Lewis: “irregular or fibrillatory waves and irregular ventricular response” or “ absent atrial activity with grossly irregular ventricular response”
WHY ATRIAL FIBRILLATION IS IMPORTANT? Atrial fibrillation is the most common sustained arrhythmia 6% over the age of 65 experience it Responsible for 15% strokes Atrial fibrillation accounts for 1/3 of all patient discharges with arrhythmia as principal diagnosis. Baily D. J Am Coll Cardiol . 1992;19(3):41A
PATHOGENESIS
PATHOGENESIS
CASUAL ASSOCIATION FACTORS
CASUAL ASSOCIATION FACTORS
PATTERNS OF ATRIAL FIBRILLATION
TYPES OF ATRIAL FIBRILLATION
SYMPTOMS Asymptomatic Symptomatic Decreased cardiac output Irregular rapid ventricular rate,loss of atrial contraction,reduced filling of ventricle Palpitations Dyspnoea Chest pain Dizziness , Syncope Neurological deficits for TIA, stroke Systemic embolism
EUROPEAN HEART RHYTHM ASSOCIATION symptom class
DIAGNOSIS & WORKUP
ATRIAL FIBRILLATION ON ECG 1.Lack of discrete P waves . 2.Fibrillatory or f waves at a rate generally between 350 & 600 beats/ minute,the f waves vary continuously in amplitude, morphology, and intervals. 3.Ventricular response follows no repetitive pattern, the variability in the intervals between QRS complexes is “irregularly irregular .” ventricular rate(in absence of AV nodal blocking agents or intrinsic conduction disease)ranges between 90- 170beats/min . 4.The QRS complexes are narrow unless AV conduction through the His Purkinje system is abnormal due to functional (rate-related) aberration, pre-existing bundle branch or fascicular block, or ventricular pre excitation with conduction down the accessory pathway.
ATRIAL FIBRILLATION WITH APPARENTLY REGULAR PULSE Atrial Fibrillation with complete heart block Patient on verapamil on pacemaker ventricular tachycardia very fast or very slow ventricular response