Atropine sulfate injections administration

Atropine sulfate injections administration

1. Atropine Sulfate Injections Administration JOANNA BONDOC U1080511 MAT1008 Presentation 1

2. Drug Use Antimuscarinic Indications Antisialogogue Bronchial secretion reduction Prevent cholinergic cardiac effects Increase ventricular irritability assoc with acute MI and sinus bradycardia Antidote for Inadvertent overdose of cholinergic drugs Cholinesterase poisoning such as organophosphorus insecticides MAT1008 Presentation 2

3. Contraindications Do NOT administer if patient has: Severe ulcerative colitis or Toxic megacolon complicating ulcerative colitis GI obstruction Closed angle glaucoma Obstructive uropathy Myasthenia gravis MAT1008 Presentation 3

4. Tachycardia due to cardiac insufficiency Thyrotoxicosis Acute haemorrhage with unstable CV status Fever Prostate enlargement Pregnancy induced hypertension MAT1008 Presentation 4

5. Interactions Other anticholinergics Antihistamines, antidepressants, antipsychotic, procainamide, quinidine, thiazides Amantadine Digitalis, cholinergics , neostigmine MAT1008 Presentation 5

6. Adverse Effects CV effects Tachycardia Palpitations Reduced secretions Bronchial plug Constipation Urinary difficulty MAT1008 Presentation 6

7. Retention Mydriasis Cyclopegia Blurred vision Photophobia flushed, hot dry skin MAT1008 Presentation 7

8. Precautions Use with caution adults over 40 years of age Pregnant Children Lactating Children with Down syndrome Glaucoma risk May convert partial organic pyloric stenosis into complete obstruction MAT1008 Presentation 8

9. Medication Administration Rights MAT1008 Presentation 9

10. Conlusion Atropine Sulfate Injection is an antimuscurinic drug use for secretion reduction. It is also an antidote for organophosphate poisoning. It is contraindicated with patients with severe ulcerative colitis, GI obstruction, glaucoma and pregnancy induced hypertension. The side effects are tachycardia, reduced secretion, urinary difficulty, bronchial plug, photophobia, blurred vision and hot dry skin Use with caution to individuals who are over 40 years old, children with down syndrome, lactating mothers and pregnant women MAT1008 Presentation 10

11. Questions Why atropine sulfate injection is needed before an operation procedure? What are the signs and symptoms to watch out if there is an adverse effect after administering atropine sulfate? Email: [email protected] MAT1008 Presentation 11

12. Reference MAT1008 Presentation 12