Name: MD. Zahirul Islam Roll:333 Batch:12 th Presentation of autoimmune disease
A disease in which the body produces antibodies that attack its own tissues, leading to the deterioration and in some cases to the destruction of such tissue. autoimmune disease
They are mainly two types 1. Systemic disorders 2. Local disorders Types of auto immune disease
Systemic disorders involve autoantibodies that are not specific to antigens found on certain tissues. Examples include: Systemic lupus erythematosus (SLE) Goodpasture’s syndrome Sarcoidosis Scleroderma Rheumatoid arthritis Dermatomyositis Systemic disorders
Examples of local disorders that are specific to a particular tissue or organ Dermatomyositis Psoriasis Vitiligo Alopecia areata Hemolytic anemia Antiphospholipid antibody syndrome Pernicious anemia Local disorders
Autoimmune diseases affect many parts of the body. The most common organs and tissue affected are: joints muscles skin red blood cells blood vessels connective tissue endocrine glands symptoms
Diagnosed by clinical symptoms. Confirmed by detecting the auto Ab in the serum of the patients. Autoantibodies are demonstrated by immunoflurescent Ab test, haemagglutination , Complement fixation, immunodiffusion , Radio immuno assay, etc. Diagnosis of Auto immune disease
Some autoimmune diseases are treated with medications that alleviate specific symptoms. Haemolytic anaemia : Treated with Vit B 12 Throtoxicosis : Treated with antithyroid drugs. Myasthenia Gravis: Treated with Choline estrase inhibitors Rhemotoid Arthritis: Anti-inflammatory drugs Lupes Erythematosus : Treated with immono suppresive or antimitiotic drugs such as Corticosteoid , Treatment
• Autoimmune diseases and conditions exist when the body produces abnormal cells, which attack the body, itself • Most autoimmune diseases strike women more often than men • The causes of autoimmune diseases are not known but some autoimmune diseases seem to run in families • Strike any part of the body, symptoms vary widely and diagnosis and treatment are often difficult • Medical science is striving to design therapies that prevent autoimmune diseases Summary