bhanga 64.pptx

class ppt

1. BhangA Guided by –Dr. Adarsha sir Dr. Shivanand sir Presented by –Sahana .S

2. Content Introduction Classification Morphology Active principles Mode of action Rasa panchaka Forms and preparation of cannabis Shodhana Indication Signs and treatment Medico legal importants Recent research updates

3. Introduction cannabis is a generic term used to denote several psychoactivepreparation of the plant Cannabis sativa. It is the oldest psychoactive substances used by man It is widely used as recreational substances & in medicinal drugs. It is called as the gateway drug. It is more commonly called as marijuana. Other names - weed, pot, grass, herb, maryjane etc...

4. Scientific classification Botanical name: Cannabis sativa Family : cannabaceae English - Indian Hemp Kannada- Bhangi soppu Hindi - bhang, ganja, charas Sanskrit synonyms – Vijaya Madani Shivapriya etc Varieties:sub species 1. Cannabis sativa 2. Cannabis indica 3. Cannabis ruberalis

5. Classification According to Modern 1. Neurotic cerebral poison 2. Stupefying poison According to ayurveda 1. Sthavara -visha 2. Upavisha- Rasatarangini 3. Moolavisha-Sushruta

6. Morphology Habitat-Native to central & southern Asia. Habit -A erect annual herbaceous & scarcelybranched plant of height 1-5meters. Leaves-Stalked palmate, alternate. Flowers-Small, pale yellow green, Dioecious. Fruits Ovate flat. Seeds- flat seeds, achene.

7. Active principles Cannabis is a complex plant with over 400 chemical entities of which more than 60 are cannabinoids
Delta-9-tetrahydrocannabinol (THC)- major psychoactive
Cannabidiol (CBD)& Cannabinol- non psychoactive

8. Mode of action Cannabinoid receptors are CB1 & CB2 receptors are called as endocannabinoid receptors present in brain and other organs. Both THC & CBD will bind to cannabinoid receptors,while they havehigh lipophilicity so they rapidly distribute to brain, adipose tissue, &other organs of the body. THC being psychoactive stimulant, it effect pain perception, cognition, memory,reward,motor coordinationetc Toxic part when taken in excess of all parts of plant are toxic.

9. Rasa panchaka Rasa : Tikta Guna : Laghu, tikshna, vyavahi Virya : Ushna Vipaka : Katu Prabhava : mada Karma : vatahara&kaphahara Part used Leaves, flowers, shoot, fruits, seeds, resin…

10. Forms and preparation of cannabis Bhang- dried leaves, fruits & shoot With sugar, black pepper made in paste form consumed in holy festivals Color – brownish THC -15%

11. Ganja – flowering tops of female plant.
It is usually smoked with tobacco.
Color-rusty green
THB – 25%

12. Charas/hashish - resinous exudate from Leaves & stem which is dried & compressed in to blocks, it is smoked with tobacco. Color-dark green THC-25-40%

13. Shodhana Leaves of bhang tied in cloth, boiled in cows’smilk for 3 hours using dolayantra.then it is washed with water, dried and roasted with cow’s ghee on lowL flame.

14. Indications Muscle pain Insomnia Diarrhea Psychiatric disorders Convulsions Glaucoma Schizophrenia Epilepsy etc.. External application Bhang leaves paste is applied externally to relieve pain & increasewarmth. It is also used in worm infested wounds & in atopic dermatitis It is applied over piles mass to shrink it

15. As per the ayurveda Bhang Uses दीपनी पचना अतिसारहरा ‘ द्वजभङ्गहरा निद्रप्रदयिनी प्रलपनाशिनी धनुः स्तम्भहरा आन्त्रशुलहरा वृक्कशुलहर

16. Formulation Jatiphala curna Madanodaya modaka Trailokyavijaya vati Bruhat kameshwara modaka Agnikumar Rasa Pusphpadhanwa rasa Nirdrodiya rasa bhanumutrantaka rasa

17. Action and metabolism The THC is lipid soluable & rapidly absorbed in blood after inhalation. It is highly protein bound & quickly redistributed from blood in to other tissues. About 1% penetrates in to blood brain barrier About 2/3 of drug is excreted via enterohepatic circulation in to faeces. Remaining 1/3 is removed via kidneys. Most metabolites of TCH are produced in liver.

18. Signs and symptoms As per modern Two stages occur: Acute Intoxication 1. Stage of excitement or euphoria
2. Stage of narcosis As per ayurveda Poisoning due to bhang exhibited following symptoms-
timira (opthalmic disorders)
manovibhrama (mental confusion)
apasmrti (transient loss of memory)
pralapa (delirium)
Vanti(vomiting)
Kanthasuskata( dryness of throat

19. In acute intoxication of bhang mortality is rare, the individually pass in to deep sleep and wake up without depression .Rarely, drowsiness may be followed by coma,collapse & death may occur form respiratory paralysis.

20. Route of administration

21. Fatal period Approximately around 12-24 hours Fatal dose and period

22. Features of chronic intoxication 1.Loss of weight
2. Loss of appetite
3. Loss of libido
4.Moral deterioration
5. General weakness
6.Emaciaton
7. Delirium
8.Pscychotic disorder etc.

23. Run amok It is psychotic disturbance usually seen in chronic cannabies users or even first time user of Cannabis. it is characterized by eager desire of the person to commit murders.
He first kills the person against whom he have a enmity and kills anyone who come in the way until the homicidal tendency lasts.
then he may commit suicide or he may surrender himself.

24. Withdrawal symptoms -It is usually seen in chronic cannabis users.
-This may include as follows
Tremors
Nystagmus
Sweating
Nausea & vomiting etc,

25. Treatment As per ayurveda - शिरस्नान with अतिशीत जल
-गो दुग्ध with सित for consumption… As per Modern -inducing vomiting
-stomach wash with warm water
- cold water irrigation over the head
- strong tea or coffee for ingestion
-500ml of 50% glucose
-2 mg naloxone
-5-10 mg of diazepam if aggressive
- if necessary saline purgatives

26. Postmortem findings findingNot characteristic Resembles signs of asphyxia Medico-legal importance Accidental ingestion or inhalation Overindulgence To strengthen the nerves before committing a crime or bold act• Used as stupefying poison

27. Recent Research updates cannabis may have benefit for use in treatment of neuropathic pain, with limited data for use in rheumatic pain. However, there are both short- term and long-term adverse effects with cannabis use that should be monitored in those who use cannabis for medicinal purposes, which include worsened anxiety and potential development of cannabis use disorder