Blaschkoid dermatitis

1. BLASCHKOID DERMATITIS

2. Introduction 1901: German dermatologist Alfred Blaschko (1858-1922) ; retrospective No Nervous , Vascular or Lymphatic correspondence developmental growth pattern of the skin; pattern of Ectodermal Migratio n and Proliferation from Neural Crest

3. V -shape – Upper Back, Neck, Upper Trunk S-shape – Lateral Trunk I nverted U-shape - breast area / Upper Arms P erpendicular - lower extremities, Forearms ‘Respect the Midline’ Koebner's phenomenon but the curvature of the lesions does not support this hypothesis Less defined on the head and neck Happle et al  posterior scalp whereas Bolognia et al  lateral aspect face and neck Equivalent over teeth and eyes

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6. Embryological Etiological basis No Vascular / Nervous / Lymphatic Jackson – localization determined by the dermal tissues ? I nborn error of morphogenesis due to a single mutant gene ? stretching of the skin during embryogenesis ? Mosaicism and Lyonization  

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8. Langer's lines / C leavage lines , - correspond to the natural orientation of Collagen / Muscle fibres . Used in forensic science & surgical techniques.

9. Kraissl's lines –anatomical Tension skin lines ; Cadavers Cox – Tension Skin Lines Borges – Relaxed TSL

10. Voigt Lines – Pigmentary demarcatory lines over body ; the boundaries of the Areas of distribution of the cutaneous nerve stems ; attributed to hormones

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