BONE HISTOLOGY SLIDES FOR LEARNERS AND TURORS

Nice notes for excellence

1. Histology of Bone
Dr PunitaManik
Professor
Department of Anatomy
K G Medical University UP
Lucknow

2. Objectives
•Introduction
•Functions of Bone
•Composition of Bones
•Classification of Bones
•Histology of Bones
•Clinical

3. Bone
•Is a rigid form of scleralconnective tissuein
which the extracellular matrix is impregnated
with inorganic salts mainly calcium, phosphate
and carbonate, providing hardness
Rigidity and hardness is provided by
the matrix which is impregnated with
inorganic salts

4. Functions
•Forms skeletal framework
•Attachment to muscles
•Serves as lever for muscular actions
•Bears body weight
•Protects vital organs
•Stores calciuum, phoshateand other ions
•Contains haemopoietictissue, the bone
marrow

5. Composition of Bone
•1.Cells -Osteoprogenitor cells
• -Osteoblast
-Osteocyte
-Osteoclast
•2.Fibres(95%)-
-collagen fibreType1
•3.Ground substance(5%)
Inorganic Part
-Calcium phosphate 85%
-calcium carbonate 10%
Organic Part:
-Collagen
-Ground substance
Osteocyte
Osteoclast

6. Cells of Bone

7. Bone Cells

8. Function of Bone Cells
Newly formed unmineralizedbone….OSTEOID
Osteoclastsare seen in specialized
depression…….Howship’sLacunae

9. Osteoclast

10. Bone Membranes
•Periosteum
•Endosteum

11. Bone Membranes

12. Types of Bones
Morphologically:
•Compact Bone and Spongy or cancellousBone
Arrangement of Collagen Bundles:
•Lamellar and Woven Bone
Developmentally:
•Cartilage Bone and membrane Bone

13. Compact and Spongy bone

15. Structure of Compact Bone
•Circumferential System
•Periosteal
•Endosteal
•HaversianSystem: Most Characteristic
feature. Also Known as OSTEON: IS the
Structural and Functional unit
•Interstitial System

16. Haversianand Volkmann’s Canal

17. Longitudinal section of HaversianCanals and
Horizontal sections of Volkmann’s Canal

18. Compact bone

19. Compact Bone

20. Compact Bone

21. Multiple Osteons

22. An Osteocyte

32. Cancellousor Spongy Bone
•Slender bony trabeculae
that branch and
anastomosewith one
another.
•Enclose irregular marrow
spaces containing blood
vessels and haemopoietic
tissue that give rise to
new blood vessels.
•They receive nutrition
from blood vessels in the
bone marrow

33. Examples of Cancellousbone

34. CancellousBone

37. Spongy Bone

38. Important facts
VITAMINS
•VitD-absorption of Ca
from small intestine
•VitC: Collagen synthesis
•VitA-Ossification
HORMONES
•Parathyroid Hormone:
activates osteoclaststo
resorbbone , therefore
increased Ca in inblood.
•Calcitonin: inhibits bone
resorptionby
osteoclasts. Decreased
Ca in blood

39. MCQ
Periosteumis absent over the following EXCEPT
1.Articular surface of bone
2.Sesamoid bone
3.Site of attachment of tendons and ligaments
to the bone
4.Shaft of long bones

40. MCQ
Osteocytesmay be identified by the presence of
1.Many Nuclei
2.Lacuna around the cell
3.Lysosomes
4.Ingested particles

41. MCQ
Alkaline phosphataseactivity can be
demonstrated in
1.Osteoblasts
2.Osteocytes
3.Osteoclasts
4.Osteoprogenitor cells

42. MCQ
Spongy bone can be identified histologically
by the presence of
1.Haversian canal and concentric bony lamellae
2.Bony trabeculaeand marrow cavity
3.Interstitial Lamellae
4.Volkmann’s Canal

43. MCQ
The vitamin necessary for the absorption of
calcium from small intestine is
1.A
2.B
3.C
4.D

44. Identify the given slide

45. Identify the slide

46. Fill in the Blank
•The Hardness and rigidity of
bone is due to the presence of
……………………………….

47. Fill in the Blank
•Newly formed unmineralized
matrix is called
………………………………………

48. Fill in the Blank
•The thin vascular membrane that
lines the marrow cavity is
………………………………….

49. Fill in the Blank
•Osteoclastsare found in
specialized depressions on the
surface of the bone called
………………………………………….

50. Osteon

51. Identification Points
•Osteons
•Haversian
Canal
•Different
types of
Lamelle