breast Cancer conference Presentation PPT

breast Cancer conference Presentation PPT

1. Dr. Uma Sharma MBBS, MS General Surgeon, DNB. MCH Onco Surgeon. Laparoscopic Surgeon.

2. FORMERLY AT Acharya Shree Bhikshu Hospital, New Delhi. Sarojini Naidu Medical College, Agra. F. H. Medical College & Hospital, Agra. Himalayan institute of Medical Sciences, Dehradun, Uttarakhand. Lady Hardinge Medical College, New Delhi. R.M.L. Hospital, New Delhi.

3. INTRODUCTION Head and neck cancers encompass a variety of malignancies affecting the oral cavity, pharynx, larynx, sinuses, and other regions. Early detection and timely intervention are crucial for improving survival rates and quality of life. This presentation will explore the importance of early detection, screening strategies, and the role of biopsy in the diagnosis and management of head and neck cancer.

4. Epidemiology Head & Neck SCC (HNSCC)- 90% of all H&N Cancers Usual age of 40; Salivary gland and nasopharyngeal cancers (NPCs) - younger age Causative factors Tobacco use - smoking/ smokeless tobacco – not associated with SMF betel leaf/ areca nut/lime use – esp. Sub-mucous fibrosis Alcohol ( also synergistic with smoking) HPV infection (High Risk HPV - esp. HPV 16) – in OPSCC Occupational dust etc. – Sino-nasal Cancers EBV - NPX cancers –

5. The Significance of Early Detection Early detection leads to better prognosis: Tumors identified in their early stages are more treatable. Increased survival rates: Early-stage cancers have a significantly higher 5-year survival rate compared to advanced stages. Reduced treatment intensity: Early intervention often allows for less aggressive treatments, preserving functions like speech and swallowing.

6. Screening for Head and Neck Cancer Risk Factors: Tobacco use, alcohol consumption, HPV infection, and occupational hazards. Screening Methods: Visual and physical examination by healthcare professionals. Use of imaging techniques like MRI and CT scans. HPV testing for at-risk populations. Who Should be Screened? Individuals with risk factors. People with persistent symptoms such as a sore throat, difficulty swallowing, Or unexplained weight loss.

7. CHEMOPREVENTION • Chemo-prevention with High dose 13-cis Retinoic acid 100 mg/m2/day for 12 months reduces SPT in Stage I & II • Other agents - no benefit • Retinoids and Beta-carotene can cause regression of leucoplakia

8. Role of Biopsy in Diagnosis Biopsy as the Gold Standard: Confirms the presence of cancer by analyzing tissue samples. Differentiates between benign and malignant growths. Types of Biopsies: Fine Needle Aspiration (FNA) Core Needle Biopsy Excisional and Incisional Biopsy Why Biopsy is Crucial: Provides a definitive diagnosis. Guides the treatment plan by identifying the type and stage of cancer.

9. Conclusion Early detection and regular screening are vital in the fight against head and neck cancer. Biopsies play a crucial role in confirming diagnosis and guiding treatment decisions. Increased awareness and proactive healthcare measures can significantly reduce the burden of this disease.